Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_055160                                                              17    3301
NP_001275635                                                           17    4312
NP_892006                                                              17    4312
NP_000868                                                              17    4312
NP_149062                                                              17    4312
NP_001229811                                                           17    4312
NP_060680                                                              17    4312
NP_001229812                                                           17    4312
NP_001229810                                                           17    4312
XP_006715488                                                           17    4312
XP_006715487                                                           17    4312
XP_006715486                                                           17    4312
XP_006715485                                                           17    4312
XP_006715484                                                           17    4312
XP_006715483                                                           17    4312
XP_006715482                                                           17    4312
XP_006715481                                                           17    4312
XP_006715480                                                           17    4312
XP_006715479                                                           17    4312
XP_006715478                                                           17    4312
XP_006715477                                                           17    4312
XP_006715476                                                           17    4312
XP_006715475                                                           17    4312
XP_006715474                                                           17    4312
XP_006715473                                                           17    4312
XP_006715472                                                           17    4312
XP_006715471                                                           17    4312
XP_006715470                                                           17    4312
XP_005263991                                                           17    4312
XP_005263989                                                           17    4312
XP_005263990                                                           17    4312
XP_005263988                                                           17    4312
XP_005263987                                                           17    4312
XP_005263986                                                           17    4312
NP_002102                                                              16    5631
NP_065986                                                              16    5631
NP_001070993                                                           16    5631
NP_058626                                                              16    5631
NP_071930                                                              16    5631
XP_005248029                                                           16    5631
XP_005265457                                                           16    5631
XP_005246781                                                           16    5631
XP_005246779                                                           16    5631
XP_005246778                                                           16    5631
XP_005246777                                                           16    5631
NP_001070994                                                           16    5631
NP_001166176                                                           16    7355
NP_001036024                                                           16    7355
NP_001409                                                              16    7355
NP_065789                                                              16    7355
NP_775814                                                              16    7355
XP_005247255                                                           16    7355
XP_006710330                                                           16    7355
NP_001229797                                                           15    9605
XP_006726554                                                           15    9605
XP_006726549                                                           15    9605
XP_006726536                                                           15    9605
XP_006719828                                                           15    9605
XP_003960044                                                           15    9605
XP_006716968                                                           15    9605
XP_005270863                                                           15    9605
XP_005270862                                                           15    9605
XP_006710667                                                           15    9605
XP_006710666                                                           15    9605
NP_001139108                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ILEISKL+D
Sbjct: 696 ILEISKLKD 704
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ILEISKL+D
Sbjct: 696 ILEISKLKD 704
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ILEISKL+D
Sbjct: 696 ILEISKLKD 704
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ILEISKL+D
Sbjct: 696 ILEISKLKD 704
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ILEISKL+D
Sbjct: 696 ILEISKLKD 704
>NP_055160
          Length = 2279

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ++E+S+LQD
Sbjct: 942 LVEVSRLQD 950
>NP_001275635
          Length = 538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 456 LLELEKIQD 464
>NP_892006
          Length = 8797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6559 ELSKLQD 6565
>NP_000868
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>NP_149062
          Length = 8749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6488 ELSKLQD 6494
>NP_001229811
          Length = 329

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           ILE+SK +D
Sbjct: 149 ILEVSKARD 157
>NP_060680
          Length = 390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           ILE+SK +D
Sbjct: 167 ILEVSKARD 175
>NP_001229812
          Length = 237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILEISKLQD 9
          ILE+SK +D
Sbjct: 57 ILEVSKARD 65
>NP_001229810
          Length = 347

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           ILE+SK +D
Sbjct: 167 ILEVSKARD 175
>XP_006715488
          Length = 8721

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715487
          Length = 8744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715486
          Length = 8758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715485
          Length = 8793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6518 ELSKLQD 6524
>XP_006715484
          Length = 8794

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6519 ELSKLQD 6525
>XP_006715483
          Length = 8795

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6520 ELSKLQD 6526
>XP_006715482
          Length = 8797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6559 ELSKLQD 6565
>XP_006715481
          Length = 8799

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6524 ELSKLQD 6530
>XP_006715480
          Length = 8799

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6524 ELSKLQD 6530
>XP_006715479
          Length = 8804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6566 ELSKLQD 6572
>XP_006715478
          Length = 8809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715477
          Length = 8822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6547 ELSKLQD 6553
>XP_006715476
          Length = 8823

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715475
          Length = 8827

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6566 ELSKLQD 6572
>XP_006715474
          Length = 8829

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6554 ELSKLQD 6560
>XP_006715473
          Length = 8832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_006715472
          Length = 8839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6564 ELSKLQD 6570
>XP_006715471
          Length = 8842

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6567 ELSKLQD 6573
>XP_006715470
          Length = 8846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EISKLQD 9
            E+SKLQD
Sbjct: 6571 ELSKLQD 6577
>XP_005263991
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>XP_005263989
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>XP_005263990
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>XP_005263988
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>XP_005263987
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>XP_005263986
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEISKLQD 9
           +LE+ K+QD
Sbjct: 487 LLELEKIQD 495
>NP_002102
          Length = 3144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILEISKLQD 9
            ILE++ LQD
Sbjct: 1279 ILELATLQD 1287
>NP_065986
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           LE+SK+Q+
Sbjct: 925 LEVSKIQE 932
>NP_001070993
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +++SKLQD
Sbjct: 108 VQVSKLQD 115
>NP_058626
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ++EIS+LQ+
Sbjct: 260 VVEISRLQE 268
>NP_071930
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +++SKLQD
Sbjct: 108 VQVSKLQD 115
>XP_005248029
          Length = 254

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ++EIS+LQ+
Sbjct: 179 VVEISRLQE 187
>XP_005265457
          Length = 625

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +++SKLQD
Sbjct: 108 VQVSKLQD 115
>XP_005246781
          Length = 957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           LE+SK+Q+
Sbjct: 903 LEVSKIQE 910
>XP_005246779
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           LE+SK+Q+
Sbjct: 925 LEVSKIQE 932
>XP_005246778
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           LE+SK+Q+
Sbjct: 925 LEVSKIQE 932
>XP_005246777
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           LE+SK+Q+
Sbjct: 925 LEVSKIQE 932
>NP_001070994
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +++SKLQD
Sbjct: 108 VQVSKLQD 115
>NP_001166176
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LEISKLQD 9
           L ISKLQD
Sbjct: 166 LLISKLQD 173
>NP_001036024
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LEISKLQD 9
           L ISKLQD
Sbjct: 166 LLISKLQD 173
>NP_001409
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LEISKLQD 9
           L ISKLQD
Sbjct: 166 LLISKLQD 173
>NP_065789
          Length = 1771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LEISKLQD 9
            +EISKL D
Sbjct: 1370 IEISKLTD 1377
>NP_775814
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LEISKLQD 9
           LEIS L+D
Sbjct: 722 LEISSLED 729
>XP_005247255
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LEISKLQD 9
           LEIS L+D
Sbjct: 750 LEISSLED 757
>XP_006710330
          Length = 138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILEISKLQD 9
           ++E+SKLQ+
Sbjct: 101 MVELSKLQE 109
>NP_001229797
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LEISKLQD 9
          LE+ KLQ+
Sbjct: 27 LEVKKLQE 34
>XP_006726554
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +E+SKLQ+
Sbjct: 102 VELSKLQE 109
>XP_006726549
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +E+SKLQ+
Sbjct: 124 VELSKLQE 131
>XP_006726536
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LEISKLQD 9
          +E+SKLQ+
Sbjct: 67 VELSKLQE 74
>XP_006719828
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LEISKLQD 9
          LE+ KLQ+
Sbjct: 27 LEVKKLQE 34
>XP_003960044
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +E+SKLQ+
Sbjct: 102 VELSKLQE 109
>XP_006716968
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LEISKLQD 9
           +E+SKLQ+
Sbjct: 102 VELSKLQE 109
>XP_005270863
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEISKLQ 8
           + EISKLQ
Sbjct: 270 VKEISKLQ 277
>XP_005270862
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEISKLQ 8
           + EISKLQ
Sbjct: 270 VKEISKLQ 277
>XP_006710667
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEISKLQ 8
           + EISKLQ
Sbjct: 270 VKEISKLQ 277
>XP_006710666
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEISKLQ 8
           + EISKLQ
Sbjct: 270 VKEISKLQ 277
>NP_001139108
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEISKLQ 8
           + EISKLQ
Sbjct: 270 VKEISKLQ 277
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.140    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 454,562
Number of extensions: 1096
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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