Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_001166951                                                           17    3301
NP_001166950                                                           17    3301
NP_056000                                                              17    3301
NP_001159743                                                           17    3301
NP_001273721                                                           17    3301
NP_001273723                                                           17    3301
NP_001273724                                                           17    3301
NP_113584                                                              17    3301
NP_001273722                                                           17    3301
NP_694568                                                              17    3301
XP_005262309                                                           17    3301
XP_005262308                                                           17    3301
XP_006724700                                                           17    3301
XP_005262307                                                           17    3301
XP_006724699                                                           17    3301
XP_005262306                                                           17    3301
XP_005262029                                                           17    3301
XP_005262028                                                           17    3301
XP_005262026                                                           17    3301
XP_006724637                                                           17    3301
XP_005262025                                                           17    3301
XP_005262024                                                           17    3301
XP_005262023                                                           17    3301
XP_005262022                                                           17    3301
NP_002105                                                              16    5631
XP_005249099                                                           16    5631
NP_001096080                                                           16    7355
NP_443135                                                              16    7355
XP_006725237                                                           16    7355
XP_005272597                                                           16    7355
NP_057297                                                              15    9605
NP_001241657                                                           15    9605
NP_001241658                                                           15    9605
NP_001121598                                                           15    9605
NP_005376                                                              15    9605
NP_001158508                                                           15    9605
NP_002532                                                              15    9605
NP_001003941                                                           15    9605
XP_005254846                                                           15    9605
XP_005249816                                                           15    9605
XP_005249818                                                           15    9605
XP_005265233                                                           15    9605
XP_005265231                                                           15    9605
XP_006713237                                                           15    9605
XP_006713236                                                           15    9605
XP_006713235                                                           15    9605
XP_006713234                                                           15    9605
XP_005265230                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILDRSSESQ 9
            ILDRSS+SQ
Sbjct: 1756 ILDRSSKSQ 1764

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILDRSSESQ 9
           +LDR +ESQ
Sbjct: 610 VLDRMAESQ 618
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILDRSSESQ 9
            ILDRSS+SQ
Sbjct: 1756 ILDRSSKSQ 1764

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILDRSSESQ 9
           +LDR +ESQ
Sbjct: 610 VLDRMAESQ 618
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILDRSSESQ 9
            ILDRSS+SQ
Sbjct: 1709 ILDRSSKSQ 1717

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILDRSSESQ 9
           +LDR +ESQ
Sbjct: 610 VLDRMAESQ 618
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILDRSSESQ 9
            ILDRSS+SQ
Sbjct: 1788 ILDRSSKSQ 1796

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILDRSSESQ 9
           +LDR +ESQ
Sbjct: 610 VLDRMAESQ 618
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILDRSSESQ 9
            ILDRSS+SQ
Sbjct: 1788 ILDRSSKSQ 1796

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILDRSSESQ 9
           +LDR +ESQ
Sbjct: 610 VLDRMAESQ 618
>NP_001166951
          Length = 414

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 210 ILDRSSE 216
>NP_001166950
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 259 ILDRSSE 265
>NP_056000
          Length = 516

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 312 ILDRSSE 318
>NP_001159743
          Length = 1277

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ILDRSSE 7
            ILDRSSE
Sbjct: 1074 ILDRSSE 1080
>NP_001273721
          Length = 1339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    ILDRSSE 7
            ILDRSSE
Sbjct: 1136 ILDRSSE 1142
>NP_001273723
          Length = 596

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 393 ILDRSSE 399
>NP_001273724
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 371 ILDRSSE 377
>NP_113584
          Length = 4374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3229 ILQRSSESE 3237
>NP_001273722
          Length = 512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 309 ILDRSSE 315
>NP_694568
          Length = 652

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 449 ILDRSSE 455
>XP_005262309
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262308
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724700
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262307
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724699
          Length = 521

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 317 ILDRSSE 323
>XP_005262306
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ILDRSSE 7
           ILDRSSE
Sbjct: 319 ILDRSSE 325
>XP_005262029
          Length = 4240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3095 ILQRSSESE 3103
>XP_005262028
          Length = 4341

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3196 ILQRSSESE 3204
>XP_005262026
          Length = 4359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3229 ILQRSSESE 3237
>XP_006724637
          Length = 4365

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3220 ILQRSSESE 3228
>XP_005262025
          Length = 4373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3228 ILQRSSESE 3236
>XP_005262024
          Length = 4374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3229 ILQRSSESE 3237
>XP_005262023
          Length = 4374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3229 ILQRSSESE 3237
>XP_005262022
          Length = 4374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ILDRSSESQ 9
            IL RSSES+
Sbjct: 3229 ILQRSSESE 3237
>NP_002105
          Length = 2718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DRSSESQ 9
           DRS+ESQ
Sbjct: 549 DRSAESQ 555
>XP_005249099
          Length = 2026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   DRSSESQ 9
           DRS+ESQ
Sbjct: 549 DRSAESQ 555
>NP_001096080
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDRSSES 8
           +DRSSES
Sbjct: 671 VDRSSES 677
>NP_443135
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDRSSES 8
           +DRSSES
Sbjct: 671 VDRSSES 677
>XP_006725237
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDRSSES 8
           +DRSSES
Sbjct: 525 VDRSSES 531
>XP_005272597
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDRSSES 8
           +DRSSES
Sbjct: 672 VDRSSES 678
>NP_057297
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDRSSE 7
           LDRSSE
Sbjct: 368 LDRSSE 373
>NP_001241657
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILDRSSES 8
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_001241658
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILDRSSES 8
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_001121598
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILDRSSES 8
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_005376
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 683 DRSSES 688
>NP_001158508
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILDRSSES 8
           I+D+SSE+
Sbjct: 289 IIDKSSEN 296
>NP_002532
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILDRSSES 8
           I+D+SSE+
Sbjct: 293 IIDKSSEN 300
>NP_001003941
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILDRSSES 8
           I+D+SSE+
Sbjct: 293 IIDKSSEN 300
>XP_005254846
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDRSSE 7
           LDRSSE
Sbjct: 138 LDRSSE 143
>XP_005249816
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILDRSSES 8
           I+D+SSE+
Sbjct: 308 IIDKSSEN 315
>XP_005249818
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILDRSSES 8
           I+D+SSE+
Sbjct: 304 IIDKSSEN 311
>XP_005265233
          Length = 1163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 383 DRSSES 388
>XP_005265231
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 430 DRSSES 435
>XP_006713237
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713236
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713235
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713234
          Length = 1436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 683 DRSSES 688
>XP_005265230
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DRSSES 8
           DRSSES
Sbjct: 683 DRSSES 688
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.114    0.255 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 382,569
Number of extensions: 449
Number of successful extensions: 58
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package