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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    2528
XP_006714104                                                           17    2528
XP_005265800                                                           17    2528
XP_006714103                                                           17    2528
XP_006714102                                                           17    2528
NP_000531                                                              17    4312
NP_001036188                                                           17    4312
XP_006723382                                                           17    4312
XP_006723381                                                           17    4312
XP_006723380                                                           17    4312
NP_001180442                                                           16    5631
NP_001180443                                                           16    5631
NP_060434                                                              16    5631
NP_001180444                                                           16    5631
XP_006712111                                                           16    5631
XP_006712110                                                           16    5631
XP_006712109                                                           16    5631
NP_060485                                                              16    7355
NP_001171711                                                           16    7355
NP_001177344                                                           16    7355
NP_116176                                                              16    7355
NP_647476                                                              16    7355
NP_005632                                                              16    7355
XP_006716165                                                           16    7355
XP_006716164                                                           16    7355
XP_006716163                                                           16    7355
XP_005247896                                                           16    7355
XP_006713857                                                           16    7355
NP_940870                                                              15    9605
XP_006715494                                                           15    9605
XP_006715493                                                           15    9605

>NP_006197
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKLV TLTV
Sbjct: 269 IKLVYTLTV 277



>XP_006714104
          Length = 832

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKLV TLTV
Sbjct: 294 IKLVYTLTV 302



>XP_005265800
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKLV TLTV
Sbjct: 269 IKLVYTLTV 277



>XP_006714103
          Length = 1111

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKLV TLTV
Sbjct: 291 IKLVYTLTV 299



>XP_006714102
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKLV TLTV
Sbjct: 294 IKLVYTLTV 302



>NP_000531
          Length = 5038

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IKLVSTLTV 9
            +KLVSTL V
Sbjct: 1842 LKLVSTLLV 1850



>NP_001036188
          Length = 5033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IKLVSTLTV 9
            +KLVSTL V
Sbjct: 1842 LKLVSTLLV 1850



>XP_006723382
          Length = 5027

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IKLVSTLTV 9
            +KLVSTL V
Sbjct: 1842 LKLVSTLLV 1850



>XP_006723381
          Length = 5031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IKLVSTLTV 9
            +KLVSTL V
Sbjct: 1841 LKLVSTLLV 1849



>XP_006723380
          Length = 5032

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IKLVSTLTV 9
            +KLVSTL V
Sbjct: 1842 LKLVSTLLV 1850



>NP_001180442
          Length = 501

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 363 LVSTLTV 369



>NP_001180443
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 300 LVSTLTV 306



>NP_060434
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 323 LVSTLTV 329



>NP_001180444
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 294 LVSTLTV 300



>XP_006712111
          Length = 264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 126 LVSTLTV 132



>XP_006712110
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 249 LVSTLTV 255



>XP_006712109
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LVSTLTV 9
           LVSTLTV
Sbjct: 307 LVSTLTV 313



>NP_060485
          Length = 855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKL+ST+ +
Sbjct: 320 IKLISTMEI 328



>NP_001171711
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IKLVSTLTV 9
           IKL+ST+ +
Sbjct: 320 IKLISTMEI 328



>NP_001177344
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 619 VKLVSTAT 626



>NP_116176
          Length = 797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLVSTLTV 9
           K+VSTL+V
Sbjct: 669 KIVSTLSV 676



>NP_647476
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>NP_005632
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>XP_006716165
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 572 VKLVSTAT 579



>XP_006716164
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 572 VKLVSTAT 579



>XP_006716163
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           +KLVST T
Sbjct: 582 VKLVSTAT 589



>XP_005247896
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLVSTLTV 9
           K+VSTL+V
Sbjct: 374 KIVSTLSV 381



>XP_006713857
          Length = 560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KLVSTLTV 9
           K+VSTL+V
Sbjct: 432 KIVSTLSV 439



>NP_940870
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IKLVSTLT 8
            I L+STLT
Sbjct: 1191 IHLISTLT 1198



>XP_006715494
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLVSTLT 8
           I L+STLT
Sbjct: 965 IHLISTLT 972



>XP_006715493
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IKLVSTLT 8
            I L+STLT
Sbjct: 1191 IHLISTLT 1198



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.134    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 249,281
Number of extensions: 273
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)