Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001014431                                                           16    7355
NP_005154                                                              16    7355
NP_001014432                                                           16    7355
NP_857596                                                              16    7355
XP_005267458                                                           16    7355
XP_005273859                                                           16    7355
NP_001193658                                                           15    9605
NP_859029                                                              15    9605
NP_005456                                                              15    9605
NP_001617                                                              15    9605
NP_004534                                                              15    9605
NP_001258137                                                           15    9605
NP_001229957                                                           15    9605
NP_001229956                                                           15    9605
NP_001157980                                                           15    9605
NP_001157979                                                           15    9605
XP_006725026                                                           15    9605
XP_006725025                                                           15    9605
XP_006725024                                                           15    9605
XP_006725023                                                           15    9605
XP_006725022                                                           15    9605
XP_006723148                                                           15    9605
XP_006723147                                                           15    9605
XP_006723146                                                           15    9605
XP_006723145                                                           15    9605
XP_006723144                                                           15    9605
XP_006719480                                                           15    9605
XP_006719479                                                           15    9605
XP_006719478                                                           15    9605
XP_006719477                                                           15    9605
XP_006719476                                                           15    9605
XP_006719475                                                           15    9605
XP_005262788                                                           15    9605
XP_005246674                                                           15    9605
XP_005246673                                                           15    9605
XP_005246672                                                           15    9605
XP_005246668                                                           15    9605
XP_005246667                                                           15    9605
XP_005246665                                                           15    9605
XP_006712605                                                           15    9605
XP_006712604                                                           15    9605
XP_005246663                                                           15    9605
XP_005246660                                                           15    9605
XP_005246661                                                           15    9605
XP_005246659                                                           15    9605
XP_005246658                                                           15    9605
XP_005246657                                                           15    9605
XP_005246656                                                           15    9605
XP_005246655                                                           15    9605
XP_005246654                                                           15    9605
XP_005246653                                                           15    9605
XP_005246652                                                           15    9605
XP_005246649                                                           15    9605
XP_005246651                                                           15    9605
XP_005246650                                                           15    9605
XP_005246648                                                           15    9605
XP_005246647                                                           15    9605
XP_006711789                                                           15    9605
XP_005273054                                                           15    9605
XP_006711788                                                           15    9605
XP_005273052                                                           15    9605
XP_005273051                                                           15    9605
NP_001095940                                                           15    9605
NP_000663                                                              15    9605
>NP_001014431
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV+VAK
Sbjct: 183 KEVIVAK 189
>NP_005154
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV+VAK
Sbjct: 183 KEVIVAK 189
>NP_001014432
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV+VAK
Sbjct: 183 KEVIVAK 189
>NP_857596
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IKEVLVAKQ 9
           IKE ++AKQ
Sbjct: 404 IKEKMLAKQ 412
>XP_005267458
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV+VAK
Sbjct: 183 KEVIVAK 189
>XP_005273859
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IKEVLVAKQ 9
           IKE ++AKQ
Sbjct: 404 IKEKMLAKQ 412
>NP_001193658
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>NP_859029
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>NP_005456
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>NP_001617
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>NP_004534
          Length = 6669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>NP_001258137
          Length = 8560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>NP_001229957
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 123 KEVIIAK 129
>NP_001229956
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 123 KEVIIAK 129
>NP_001157980
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>NP_001157979
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_006725026
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_006725025
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 120 KEVIIAK 126
>XP_006725024
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_006725023
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_006725022
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_006723148
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>XP_006723147
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>XP_006723146
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>XP_006723145
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>XP_006723144
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 185 KEVIIAK 191
>XP_006719480
          Length = 2035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1634 LKEVLVA 1640
>XP_006719479
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1658 LKEVLVA 1664
>XP_006719478
          Length = 2078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1681 LKEVLVA 1687
>XP_006719477
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1681 LKEVLVA 1687
>XP_006719476
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1681 LKEVLVA 1687
>XP_006719475
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    IKEVLVA 7
            +KEVLVA
Sbjct: 1681 LKEVLVA 1687
>XP_005262788
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKEVLVAK 8
           IKE+ VAK
Sbjct: 153 IKEISVAK 160
>XP_005246674
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246673
          Length = 8018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246672
          Length = 8277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246668
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246667
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246665
          Length = 8339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_006712605
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_006712604
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246663
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246660
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246661
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246659
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246658
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246657
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246656
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246655
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246654
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246653
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246652
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246649
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246651
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246650
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246648
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_005246647
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    EVLVAKQ 9
            EVL+AKQ
Sbjct: 2742 EVLLAKQ 2748
>XP_006711789
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_005273054
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 120 KEVIIAK 126
>XP_006711788
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_005273052
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>XP_005273051
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KEVLVAK 8
           KEV++AK
Sbjct: 181 KEVIIAK 187
>NP_001095940
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKEVLVAK 8
           IKE+ VAK
Sbjct: 153 IKEISVAK 160
>NP_000663
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKEVLVAK 8
           IKE+ VAK
Sbjct: 153 IKEISVAK 160
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.132    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,393
Number of extensions: 538
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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