Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              17    2528
NP_001263689                                                           17    2528
NP_001119584                                                           17    2528
NP_001119586                                                           17    2528
NP_001263625                                                           17    2528
NP_001119590                                                           17    2528
NP_001263690                                                           17    2528
NP_001119585                                                           17    2528
NP_001263624                                                           17    2528
NP_001119588                                                           17    2528
NP_001119587                                                           17    2528
NP_001119589                                                           17    2528
NP_001263627                                                           17    2528
NP_001263628                                                           17    2528
NP_001263626                                                           17    2528
NP_001091947                                                           17    4312
NP_002083                                                              17    4312
XP_005265742                                                           17    4312
XP_005265738                                                           17    4312
NP_000528                                                              16    7355
NP_001035987                                                           16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
XP_006723282                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_002912                                                              15    9605
NP_001012740                                                           15    9605
NP_001012738                                                           15    9605
NP_036558                                                              15    9605
NP_000403                                                              15    9605
NP_116166                                                              15    9605
NP_079120                                                              15    9605
NP_612392                                                              15    9605
NP_001073996                                                           15    9605
NP_872332                                                              15    9605
XP_005257749                                                           15    9605
XP_006722157                                                           15    9605
XP_005256293                                                           15    9605
XP_006721399                                                           15    9605
XP_006721398                                                           15    9605
XP_006720125                                                           15    9605
XP_005267432                                                           15    9605
XP_005267431                                                           15    9605
XP_005267430                                                           15    9605
XP_006716388                                                           15    9605
XP_005247472                                                           15    9605
XP_006712602                                                           15    9605
>NP_000537
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 254 IITLEDSSG 262
>NP_001263689
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 215 IITLEDSSG 223
>NP_001119584
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 254 IITLEDSSG 262
>NP_001119586
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 254 IITLEDSSG 262
>NP_001263625
          Length = 302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 215 IITLEDSSG 223
>NP_001119590
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 215 IITLEDSSG 223
>NP_001263690
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 215 IITLEDSSG 223
>NP_001119585
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 254 IITLEDSSG 262
>NP_001263624
          Length = 307

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 215 IITLEDSSG 223
>NP_001119588
          Length = 209

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 122 IITLEDSSG 130
>NP_001119587
          Length = 261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 122 IITLEDSSG 130
>NP_001119589
          Length = 214

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 122 IITLEDSSG 130
>NP_001263627
          Length = 182

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 95  IITLEDSSG 103
>NP_001263628
          Length = 187

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 95  IITLEDSSG 103
>NP_001263626
          Length = 234

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IITLE SSG
Sbjct: 95  IITLEDSSG 103
>NP_001091947
          Length = 318

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ITLEYSS 8
           IT+EYSS
Sbjct: 267 ITMEYSS 273
>NP_002083
          Length = 480

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ITLEYSS 8
           IT+EYSS
Sbjct: 429 ITMEYSS 435
>XP_005265742
          Length = 362

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ITLEYSS 8
           IT+EYSS
Sbjct: 311 ITMEYSS 317
>XP_005265738
          Length = 561

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ITLEYSS 8
           IT+EYSS
Sbjct: 510 ITMEYSS 516
>NP_000528
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITLEYSSG 9
           +TL YS+G
Sbjct: 145 LTLRYSTG 152
>NP_001035987
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IIT+E +SG
Sbjct: 166 IITMESASG 174
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 15433 ILTVENSSG 15441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 16516 LTLENSSG 16523
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 15558 ILTVENSSG 15566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 16641 LTLENSSG 16648
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 22857 ILTVENSSG 22865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 23940 LTLENSSG 23947
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 21930 ILTVENSSG 21938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 23013 LTLENSSG 23020
>XP_006723282
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IITLEYSSG 9
           IIT+E +SG
Sbjct: 166 IITMESASG 174
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 11170 ILTVENSSG 11178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 12253 LTLENSSG 12260
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 12529 ILTVENSSG 12537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 13612 LTLENSSG 13619
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 22485 ILTVENSSG 22493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 23568 LTLENSSG 23575
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 23991 ILTVENSSG 23999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 25074 LTLENSSG 25081
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 24498 ILTVENSSG 24506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 25581 LTLENSSG 25588
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IITLEYSSG 9
             I+T+E SSG
Sbjct: 15625 ILTVENSSG 15633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     ITLEYSSG 9
             +TLE SSG
Sbjct: 16708 LTLENSSG 16715
>NP_002912
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TLEYSSG 9
           TL+YS G
Sbjct: 167 TLDYSKG 173
>NP_001012740
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TLEYSSG 9
           TL+YS G
Sbjct: 163 TLDYSKG 169
>NP_001012738
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TLEYSSG 9
           TL+YS G
Sbjct: 163 TLDYSKG 169
>NP_036558
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLEYSSG 9
           TLE++SG
Sbjct: 738 TLEFASG 744
>NP_000403
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  IITLEYS 7
          +ITL+YS
Sbjct: 10 LITLQYS 16
>NP_116166
          Length = 1338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ITLEYSS 8
           ITL YSS
Sbjct: 840 ITLHYSS 846
>NP_079120
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITLEYSSG 9
           + LEY+SG
Sbjct: 402 LLLEYASG 409
>NP_612392
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLEYSSG 9
           +L+YSSG
Sbjct: 466 SLQYSSG 472
>NP_001073996
          Length = 2116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IITLEYSS 8
           I+TL YSS
Sbjct: 577 ILTLVYSS 584
>NP_872332
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IITLEYS 7
           +ITLEY+
Sbjct: 115 LITLEYA 121
>XP_005257749
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ITLEYSSG 9
          + LEY+SG
Sbjct: 85 LLLEYASG 92
>XP_006722157
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITLEYSSG 9
           + LEY+SG
Sbjct: 357 LLLEYASG 364
>XP_005256293
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLEYSSG 9
           +L+YSSG
Sbjct: 431 SLQYSSG 437
>XP_006721399
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLEYSSG 9
           +L+YSSG
Sbjct: 438 SLQYSSG 444
>XP_006721398
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLEYSSG 9
           +L+YSSG
Sbjct: 441 SLQYSSG 447
>XP_006720125
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IITLEYS 7
           +ITLEY+
Sbjct: 115 LITLEYA 121
>XP_005267432
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IITLEYS 7
           +ITLEY+
Sbjct: 115 LITLEYA 121
>XP_005267431
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IITLEYS 7
           +ITLEY+
Sbjct: 115 LITLEYA 121
>XP_005267430
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IITLEYS 7
           +ITLEY+
Sbjct: 115 LITLEYA 121
>XP_006716388
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ITLEYSS 8
           ITL YSS
Sbjct: 816 ITLHYSS 822
>XP_005247472
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  IITLEYS 7
          +ITL+YS
Sbjct: 10 LITLQYS 16
>XP_006712602
          Length = 2142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IITLEYSS 8
           I+TL YSS
Sbjct: 577 ILTLVYSS 584
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.134    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 582,445
Number of extensions: 814
Number of successful extensions: 64
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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