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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     390
XP_005262424                                                           20     390
NP_001714                                                              17    2528
XP_005249383                                                           17    2528
NP_003310                                                              17    4312
NP_597676                                                              17    4312
NP_001243779                                                           17    4312
NP_596869                                                              17    4312
XP_005246888                                                           17    4312
XP_006712788                                                           17    4312
XP_006712787                                                           17    4312
XP_006712786                                                           17    4312
NP_001254479                                                           17    4312
NP_597681                                                              17    4312
NP_055178                                                              16    7355
NP_001129628                                                           16    7355
NP_001264984                                                           16    7355
NP_008877                                                              16    7355
NP_003119                                                              16    7355
NP_055725                                                              16    7355
XP_005266395                                                           16    7355
XP_005274250                                                           16    7355
XP_006718734                                                           16    7355
XP_006718733                                                           16    7355
XP_005274249                                                           16    7355
XP_006718732                                                           16    7355
XP_006713658                                                           16    7355
XP_005264575                                                           16    7355
XP_006712150                                                           16    7355
XP_005264574                                                           16    7355
NP_842565                                                              16    7355
NP_000490                                                              15    9605
NP_065733                                                              15    9605
NP_056099                                                              15    9605
NP_001106962                                                           15    9605
NP_060842                                                              15    9605
XP_005262146                                                           15    9605
XP_005262145                                                           15    9605
XP_005262144                                                           15    9605
XP_005254242                                                           15    9605
XP_006710826                                                           15    9605
XP_005271086                                                           15    9605
XP_006710565                                                           15    9605
XP_006710564                                                           15    9605
XP_005270743                                                           15    9605

>NP_722576
          Length = 3080

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IINIVLEKQ 9
            IIN+VLEKQ
Sbjct: 2517 IINVVLEKQ 2525



>XP_005262424
          Length = 2875

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IINIVLEKQ 9
            IIN+VLEKQ
Sbjct: 2312 IINVVLEKQ 2320



>NP_001714
          Length = 2649

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    NIVLEKQ 9
            NIVLEKQ
Sbjct: 1599 NIVLEKQ 1605



>XP_005249383
          Length = 3186

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    NIVLEKQ 9
            NIVLEKQ
Sbjct: 2136 NIVLEKQ 2142



>NP_003310
          Length = 26926

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 11139 VINYIVEKQ 11147




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 20900 IINYVIEKR 20908




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IINIVLEKQ 9
            IIN  LEK+
Sbjct: 8336 IINYTLEKK 8344



>NP_597676
          Length = 27051

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 11264 VINYIVEKQ 11272




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 21025 IINYVIEKR 21033




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IINIVLEKQ 9
            IIN  LEK+
Sbjct: 8461 IINYTLEKK 8469



>NP_001243779
          Length = 34350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 18563 VINYIVEKQ 18571




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 28324 IINYVIEKR 28332




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     IINIVLEKQ 9
             IIN  LEK+
Sbjct: 15760 IINYTLEKK 15768



>NP_596869
          Length = 33423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 17636 VINYIVEKQ 17644




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 27397 IINYVIEKR 27405




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     IINIVLEKQ 9
             IIN  LEK+
Sbjct: 14833 IINYTLEKK 14841



>XP_005246888
          Length = 22663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IINIVLEKQ 9
            +IN ++EKQ
Sbjct: 6876 VINYIVEKQ 6884




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 16637 IINYVIEKR 16645




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IINIVLEKQ 9
            IIN  LEK+
Sbjct: 4073 IINYTLEKK 4081



>XP_006712788
          Length = 24022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IINIVLEKQ 9
            +IN ++EKQ
Sbjct: 8235 VINYIVEKQ 8243




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 17996 IINYVIEKR 18004




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IINIVLEKQ 9
            IIN  LEK+
Sbjct: 5432 IINYTLEKK 5440



>XP_006712787
          Length = 33978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 18191 VINYIVEKQ 18199




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 27952 IINYVIEKR 27960




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     IINIVLEKQ 9
             IIN  LEK+
Sbjct: 15388 IINYTLEKK 15396



>XP_006712786
          Length = 35484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 19697 VINYIVEKQ 19705




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 29458 IINYVIEKR 29466




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     IINIVLEKQ 9
             IIN  LEK+
Sbjct: 16894 IINYTLEKK 16902



>NP_001254479
          Length = 35991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 20204 VINYIVEKQ 20212




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 29965 IINYVIEKR 29973




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1     IINIVLEKQ 9
             IIN  LEK+
Sbjct: 17401 IINYTLEKK 17409



>NP_597681
          Length = 27118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             +IN ++EKQ
Sbjct: 11331 VINYIVEKQ 11339




 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     IINIVLEKQ 9
             IIN V+EK+
Sbjct: 21092 IINYVIEKR 21100




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    IINIVLEKQ 9
            IIN  LEK+
Sbjct: 8528 IINYTLEKK 8536



>NP_055178
          Length = 4579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INIVLEKQ 9
           +NIVLE++
Sbjct: 375 VNIVLEEE 382



>NP_001129628
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IINIVLEK 8
           I+NI+L K
Sbjct: 937 IVNIILNK 944



>NP_001264984
          Length = 4432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INIVLEKQ 9
           +NIVLE++
Sbjct: 228 VNIVLEEE 235



>NP_008877
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425



>NP_003119
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422



>NP_055725
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IINIVLEK 8
           I+NI+L K
Sbjct: 937 IVNIILNK 944



>XP_005266395
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INIVLEKQ 9
           +NIVLE++
Sbjct: 375 VNIVLEEE 382



>XP_005274250
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425



>XP_006718734
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425



>XP_006718733
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425



>XP_005274249
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1418 VNILLKKQ 1425



>XP_006718732
          Length = 2397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1425 VNILLKKQ 1432



>XP_006713658
          Length = 212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INIVLEKQ 9
           IN+V+EK+
Sbjct: 176 INLVIEKR 183



>XP_005264575
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1402 VNILLKKQ 1409



>XP_006712150
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422



>XP_005264574
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1415 VNILLKKQ 1422



>NP_842565
          Length = 2155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    INIVLEKQ 9
            +NI+L+KQ
Sbjct: 1402 VNILLKKQ 1409



>NP_000490
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IINIVL+
Sbjct: 307 IINIVLD 313



>NP_065733
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IINIVLEKQ 9
           +IN+V +KQ
Sbjct: 157 VINLVPDKQ 165



>NP_056099
          Length = 3375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IIN+VLE
Sbjct: 840 IINMVLE 846



>NP_001106962
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NIVLEKQ 9
          N+++EKQ
Sbjct: 89 NLIMEKQ 95



>NP_060842
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IINIVLEK 8
           ++NIVL K
Sbjct: 411 VVNIVLAK 418



>XP_005262146
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NIVLEKQ 9
          N+++EKQ
Sbjct: 89 NLIMEKQ 95



>XP_005262145
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NIVLEKQ 9
          N+++EKQ
Sbjct: 89 NLIMEKQ 95



>XP_005262144
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NIVLEKQ 9
          N+++EKQ
Sbjct: 89 NLIMEKQ 95



>XP_005254242
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IINIVL+
Sbjct: 307 IINIVLD 313



>XP_006710826
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IINIVLEK 8
           ++NIVL K
Sbjct: 411 VVNIVLAK 418



>XP_005271086
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IINIVLEK 8
           ++NIVL K
Sbjct: 411 VVNIVLAK 418



>XP_006710565
          Length = 3140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IIN+VLE
Sbjct: 548 IINMVLE 554



>XP_006710564
          Length = 3432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IIN+VLE
Sbjct: 840 IINMVLE 846



>XP_005270743
          Length = 3453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IINIVLE 7
           IIN+VLE
Sbjct: 861 IINMVLE 867



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.148    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 506,402
Number of extensions: 835
Number of successful extensions: 65
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)