Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004922                                                              16    5631
NP_757362                                                              16    5631
NP_001243390                                                           16    5631
NP_742099                                                              16    5631
NP_001037                                                              16    5631
NP_003560                                                              16    5631
NP_001139693                                                           16    5631
XP_006719087                                                           16    5631
XP_006716281                                                           16    5631
XP_006716280                                                           16    5631
XP_006710299                                                           16    5631
NP_001161870                                                           16    7355
NP_006407                                                              16    7355
NP_002407                                                              16    7355
NP_001257306                                                           16    7355
NP_001257307                                                           16    7355
NP_940683                                                              16    7355
NP_001257308                                                           16    7355
NP_001177636                                                           16    7355
NP_667340                                                              16    7355
XP_006716572                                                           16    7355
XP_006713158                                                           16    7355
XP_006713157                                                           16    7355
XP_006713156                                                           16    7355
XP_006713155                                                           16    7355
XP_006713154                                                           16    7355
XP_006713152                                                           16    7355
XP_006713151                                                           16    7355
NP_001120916                                                           15    9605
NP_001001547                                                           15    9605
NP_000063                                                              15    9605
NP_001001548                                                           15    9605
NP_001120915                                                           15    9605
NP_001077073                                                           15    9605
NP_001077075                                                           15    9605
NP_001077076                                                           15    9605
NP_001077072                                                           15    9605
NP_001077071                                                           15    9605
NP_000255                                                              15    9605
NP_001077074                                                           15    9605
NP_001276838                                                           15    9605
NP_001276837                                                           15    9605
NP_001276840                                                           15    9605
NP_783864                                                              15    9605
NP_001186728                                                           15    9605
NP_001072118                                                           15    9605
NP_003096                                                              15    9605
NP_787120                                                              15    9605
XP_006718756                                                           15    9605
XP_005252159                                                           15    9605
XP_005250772                                                           15    9605
XP_005250771                                                           15    9605
XP_005250770                                                           15    9605
XP_005262701                                                           15    9605
XP_006713670                                                           15    9605
XP_005247446                                                           15    9605
XP_006713669                                                           15    9605
>NP_004922
          Length = 210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LL+S+GV
Sbjct: 181 LVLLVSLGV 189
>NP_757362
          Length = 243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LL+S+GV
Sbjct: 181 LVLLVSLGV 189
>NP_001243390
          Length = 1196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           +ILLL+IG
Sbjct: 440 VILLLAIG 447
>NP_742099
          Length = 221

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LL+S+GV
Sbjct: 181 LVLLVSLGV 189
>NP_001037
          Length = 1212

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           +ILLL+IG
Sbjct: 440 VILLLAIG 447
>NP_003560
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           IIL+L IGV
Sbjct: 241 IILILVIGV 249
>NP_001139693
          Length = 340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  IILLLSIG 8
          +ILLLS+G
Sbjct: 10 VILLLSMG 17
>XP_006719087
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  IILLLSIG 8
          +ILLLS+G
Sbjct: 10 VILLLSMG 17
>XP_006716281
          Length = 267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LLL++GV
Sbjct: 183 VLLLLALGV 191
>XP_006716280
          Length = 388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LLL++GV
Sbjct: 304 VLLLLALGV 312
>XP_006710299
          Length = 246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IILLLSIGV 9
           ++LLL++GV
Sbjct: 162 VLLLLALGV 170
>NP_001161870
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IILLLSIGV 9
          I LLLS+G+
Sbjct: 54 IKLLLSVGI 62
>NP_006407
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IILLLSIGV 9
          I LLLS+G+
Sbjct: 54 IKLLLSVGI 62
>NP_002407
          Length = 125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IILLLSIGV 9
          IILL+ IGV
Sbjct: 12 IILLVLIGV 20
>NP_001257306
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +I LLS+G+
Sbjct: 201 VIALLSLGI 209
>NP_001257307
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +I LLS+G+
Sbjct: 201 VIALLSLGI 209
>NP_940683
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +I LLS+G+
Sbjct: 201 VIALLSLGI 209
>NP_001257308
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +I LLS+G+
Sbjct: 201 VIALLSLGI 209
>NP_001177636
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>NP_667340
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006716572
          Length = 228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +I LLS+G+
Sbjct: 201 VIALLSLGI 209
>XP_006713158
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713157
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713156
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713155
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713154
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713152
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>XP_006713151
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IILLLSIG 8
           ++LLLS+G
Sbjct: 166 VLLLLSLG 173
>NP_001120916
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001001547
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_000063
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001001548
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001120915
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>NP_001077073
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +IL+ S+G+
Sbjct: 933 VILIASVGI 941
>NP_001077075
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +IL+ S+G+
Sbjct: 933 VILIASVGI 941
>NP_001077076
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +IL+ S+G+
Sbjct: 933 VILIASVGI 941
>NP_001077072
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IILLLSIGV 9
            +IL+ S+G+
Sbjct: 1083 VILIASVGI 1091
>NP_001077071
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IILLLSIGV 9
            +IL+ S+G+
Sbjct: 1018 VILIASVGI 1026
>NP_000255
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IILLLSIGV 9
            +IL+ S+G+
Sbjct: 1084 VILIASVGI 1092
>NP_001077074
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +IL+ S+G+
Sbjct: 933 VILIASVGI 941
>NP_001276838
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 386 MILLSVGV 393
>NP_001276837
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 407 MILLSVGV 414
>NP_001276840
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 370 MILLSVGV 377
>NP_783864
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IILLLSIGV 9
            ++LLLSI +
Sbjct: 1008 LVLLLSIAI 1016
>NP_001186728
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL IGV
Sbjct: 179 LLLLLLIGV 187
>NP_001072118
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL +GV
Sbjct: 129 LLLLLGLGV 137
>NP_003096
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ILLLSIGV 9
            ++LLS+GV
Sbjct: 2146 LILLSLGV 2153
>NP_787120
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL IGV
Sbjct: 179 LLLLLLIGV 187
>XP_006718756
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL +GV
Sbjct: 120 LLLLLGLGV 128
>XP_005252159
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           +IL+ S+G+
Sbjct: 933 VILIASVGI 941
>XP_005250772
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005250771
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005250770
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILLLSIGV 9
           ++LLS+GV
Sbjct: 446 MILLSVGV 453
>XP_005262701
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IILLLSIGV 9
            ++LLLSI +
Sbjct: 999  LVLLLSIAI 1007
>XP_006713670
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IILLLSIGV 9
          ++LLL IGV
Sbjct: 44 LLLLLLIGV 52
>XP_005247446
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL IGV
Sbjct: 191 LLLLLLIGV 199
>XP_006713669
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IILLLSIGV 9
           ++LLL IGV
Sbjct: 177 LLLLLLIGV 185
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.171    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 330,441
Number of extensions: 608
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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