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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              20     509
XP_005273257                                                           20     509
NP_002411                                                              17    4312
NP_001238953                                                           17    4312
NP_001238949                                                           17    4312
NP_055723                                                              16    5631
NP_066566                                                              16    5631
NP_542119                                                              16    5631
NP_666018                                                              16    7355
NP_036471                                                              16    7355
NP_001138571                                                           16    7355
NP_060055                                                              16    7355
NP_006381                                                              16    7355
NP_945327                                                              16    7355
XP_005269724                                                           16    7355
XP_005269723                                                           16    7355
XP_006717801                                                           16    7355
NP_001035207                                                           15    9605
NP_001017967                                                           15    9605
NP_612396                                                              15    9605
NP_001007254                                                           15    9605
NP_079247                                                              15    9605
NP_001007472                                                           15    9605
NP_066003                                                              15    9605
NP_996830                                                              15    9605
NP_996829                                                              15    9605
NP_996828                                                              15    9605
NP_996827                                                              15    9605
XP_005252275                                                           15    9605

>NP_064450
          Length = 1722

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IIAMGVLLP 9
           IIAMG+LLP
Sbjct: 565 IIAMGLLLP 573



>XP_005273257
          Length = 1726

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IIAMGVLLP 9
           IIAMG+LLP
Sbjct: 565 IIAMGLLLP 573



>NP_002411
          Length = 1603

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + MG+LLP
Sbjct: 751 VIMGILLP 758



>NP_001238953
          Length = 1625

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + MG+LLP
Sbjct: 773 VIMGILLP 780



>NP_001238949
          Length = 1642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + MG+LLP
Sbjct: 790 VIMGILLP 797



>NP_055723
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   IIAMGVLLP 9
           ++++GV+LP
Sbjct: 265 VLSLGVVLP 273



>NP_066566
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           +AMG +LP
Sbjct: 301 VAMGAVLP 308



>NP_542119
          Length = 525

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IIAMGVLLP 9
           IIA  VLLP
Sbjct: 245 IIATAVLLP 253



>NP_666018
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IIAMGVLLP 9
           + A+G+L+P
Sbjct: 427 LFALGILVP 435



>NP_036471
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           I +G+LLP
Sbjct: 237 ILLGILLP 244



>NP_001138571
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IIAMGVLLP 9
           + A+G+LLP
Sbjct: 184 LYALGLLLP 192



>NP_060055
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IIAMGVLLP 9
           + A+G+LLP
Sbjct: 184 LYALGLLLP 192



>NP_006381
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IIAMGVLLP 9
           IIAM + LP
Sbjct: 172 IIAMQIFLP 180



>NP_945327
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IIAMGVL 7
           ++AMGVL
Sbjct: 431 VVAMGVL 437



>XP_005269724
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           I +G+LLP
Sbjct: 150 ILLGILLP 157



>XP_005269723
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           I +G+LLP
Sbjct: 172 ILLGILLP 179



>XP_006717801
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           I +G+LLP
Sbjct: 213 ILLGILLP 220



>NP_001035207
          Length = 1450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  IIAMGVLLP 9
          ++ MG+LLP
Sbjct: 46 LMDMGMLLP 54



>NP_001017967
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IIAMGVLL 8
           ++ MGVLL
Sbjct: 279 VLTMGVLL 286



>NP_612396
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IIAMGVLLP 9
           ++AMG+L P
Sbjct: 288 VLAMGLLGP 296



>NP_001007254
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIAMGVLLP 9
           I++MG L P
Sbjct: 126 IVSMGSLFP 134



>NP_079247
          Length = 1566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 634 VILGILLP 641



>NP_001007472
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 775 VILGILLP 782



>NP_066003
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 622 VILGILLP 629



>NP_996830
          Length = 1569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 637 VILGILLP 644



>NP_996829
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 647 VILGILLP 654



>NP_996828
          Length = 1556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 624 VILGILLP 631



>NP_996827
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 612 VILGILLP 619



>XP_005252275
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   IAMGVLLP 9
           + +G+LLP
Sbjct: 802 VILGILLP 809



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.159    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 399,985
Number of extensions: 571
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)