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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060170                                                              17    4312
NP_001229658                                                           17    4312
NP_001186637                                                           16    5631
NP_001186635                                                           16    5631
NP_036433                                                              16    5631
XP_005250782                                                           16    5631
XP_006715742                                                           16    5631
XP_006715741                                                           16    5631
XP_005249747                                                           16    5631
XP_005249746                                                           16    5631
XP_005249745                                                           16    5631
NP_001073312                                                           16    7355
NP_060839                                                              16    7355
NP_001182207                                                           16    7355
NP_002430                                                              16    7355
XP_006712843                                                           16    7355
XP_005264079                                                           16    7355
XP_006710775                                                           16    7355
XP_005263536                                                           16    7355
NP_057062                                                              15    9605
NP_689838                                                              15    9605
NP_060212                                                              15    9605
NP_001106279                                                           15    9605
NP_001186256                                                           15    9605
NP_001041677                                                           15    9605
XP_006722557                                                           15    9605
XP_006722556                                                           15    9605
NP_068747                                                              15    9605
NP_848591                                                              15    9605

>NP_060170
          Length = 219

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H++RMM K
Sbjct: 87 HMKRMMAK 94



>NP_001229658
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H++RMM K
Sbjct: 87 HMKRMMAK 94



>NP_001186637
          Length = 417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R+ MMK
Sbjct: 173 HVRKYMMK 180



>NP_001186635
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R+ MMK
Sbjct: 273 HVRKYMMK 280



>NP_036433
          Length = 1455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IHLRRM 6
           +HLRRM
Sbjct: 779 VHLRRM 784



>XP_005250782
          Length = 1441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IHLRRM 6
           +HLRRM
Sbjct: 765 VHLRRM 770



>XP_006715742
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H+R+ MMK
Sbjct: 31 HVRKYMMK 38



>XP_006715741
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H+R+ MMK
Sbjct: 31 HVRKYMMK 38



>XP_005249747
          Length = 275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H+R+ MMK
Sbjct: 31 HVRKYMMK 38



>XP_005249746
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R+ MMK
Sbjct: 311 HVRKYMMK 318



>XP_005249745
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R+ MMK
Sbjct: 324 HVRKYMMK 331



>NP_001073312
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLRRMMMK 9
            H+RRM+ K
Sbjct: 1324 HMRRMLGK 1331



>NP_060839
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           HLRR+ +K
Sbjct: 409 HLRRVQIK 416



>NP_001182207
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IHLRRM 6
           +HLRRM
Sbjct: 165 LHLRRM 170



>NP_002430
          Length = 1137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   IHLRRMMMK 9
           +H+RR++ K
Sbjct: 292 VHVRRLVAK 300



>XP_006712843
          Length = 891

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   HLRRMM 7
           HLR+MM
Sbjct: 197 HLRKMM 202



>XP_005264079
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   HLRRMM 7
           HLR+MM
Sbjct: 192 HLRKMM 197



>XP_006710775
          Length = 1759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLRRMMMK 9
            H+RRM+ K
Sbjct: 1324 HMRRMLGK 1331



>XP_005263536
          Length = 1783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    HLRRMMMK 9
            H+RRM+ K
Sbjct: 1348 HMRRMLGK 1355



>NP_057062
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  HLRRMMMK 9
          H+R +M+K
Sbjct: 83 HIRTLMLK 90



>NP_689838
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           HL+R MM+
Sbjct: 323 HLKRHMMQ 330



>NP_060212
          Length = 1178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   IHLRRMMMK 9
           +H+ ++M+K
Sbjct: 352 VHIEKIMLK 360



>NP_001106279
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R +M+K
Sbjct: 197 HIRTLMLK 204



>NP_001186256
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   HLRRMMMK 9
           H+R +M+K
Sbjct: 197 HIRTLMLK 204



>NP_001041677
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  IHLRRMM 7
          IH+RR++
Sbjct: 77 IHIRRLL 83



>XP_006722557
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   IHLRRMMMK 9
           +H+ ++M+K
Sbjct: 272 VHIEKIMLK 280



>XP_006722556
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   IHLRRMMMK 9
           +H+ ++M+K
Sbjct: 272 VHIEKIMLK 280



>NP_068747
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  IHLRRMMMK 9
          +H+ R+M+K
Sbjct: 41 LHVSRIMLK 49



>NP_848591
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   HLRRMMM 8
           HLR MM+
Sbjct: 331 HLRSMML 337



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.360    0.147    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 454,325
Number of extensions: 592
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.3 bits)
S2: 28 (15.4 bits)