Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185763                                                           21     229
NP_055459                                                              21     229
XP_006711718                                                           21     229
XP_006711716                                                           21     229
XP_006711715                                                           21     229
XP_006711714                                                           21     229
XP_006711713                                                           21     229
XP_006711712                                                           21     229
XP_006711710                                                           21     229
XP_006711709                                                           21     229
XP_005277503                                                           21     229
XP_005273038                                                           21     229
XP_006711708                                                           21     229
XP_005277500                                                           21     229
XP_006711707                                                           21     229
XP_005277499                                                           21     229
XP_006711706                                                           21     229
XP_006711705                                                           21     229
XP_006710142                                                           21     229
XP_006710141                                                           21     229
NP_001124468                                                           18    1935
NP_000850                                                              18    1935
NP_003493                                                              17    3301
NP_851393                                                              17    3301
XP_005255667                                                           17    3301
XP_005255666                                                           17    3301
XP_005255665                                                           17    3301
XP_005255664                                                           17    3301
NP_001449                                                              16    5631
NP_001120959                                                           16    5631
NP_001026881                                                           16    5631
NP_001128625                                                           16    5631
NP_036307                                                              16    5631
NP_208385                                                              16    5631
XP_005252908                                                           16    5631
XP_005273523                                                           16    5631
XP_006716387                                                           16    5631
XP_005273522                                                           16    5631
XP_005273521                                                           16    5631
XP_005273520                                                           16    5631
XP_006716386                                                           16    5631
XP_006715973                                                           16    5631
XP_006714955                                                           16    5631
NP_001121903                                                           16    5631
NP_001128626                                                           16    5631
NP_056174                                                              16    5631
NP_004604                                                              15    9605
NP_000405                                                              15    9605
NP_001186221                                                           15    9605
NP_001186220                                                           15    9605
XP_005268801                                                           15    9605
XP_005268800                                                           15    9605
XP_005268799                                                           15    9605
NP_056090                                                              15    9605
>NP_001185763
          Length = 2362

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1181 LGATFTVDA 1189
>NP_055459
          Length = 2346

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1181 LGATFTVDA 1189
>XP_006711718
          Length = 1436

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IGATFTVDA 9
           +GATFTVDA
Sbjct: 188 LGATFTVDA 196
>XP_006711716
          Length = 2411

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1247 LGATFTVDA 1255
>XP_006711715
          Length = 2428

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1181 LGATFTVDA 1189
>XP_006711714
          Length = 2429

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1181 LGATFTVDA 1189
>XP_006711713
          Length = 2432

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1184 LGATFTVDA 1192
>XP_006711712
          Length = 2473

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006711710
          Length = 2494

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1247 LGATFTVDA 1255
>XP_006711709
          Length = 2495

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1247 LGATFTVDA 1255
>XP_005277503
          Length = 2498

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_005273038
          Length = 2509

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006711708
          Length = 2512

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_005277500
          Length = 2525

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006711707
          Length = 2553

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_005277499
          Length = 2561

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006711706
          Length = 2591

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006711705
          Length = 2592

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IGATFTVDA 9
            +GATFTVDA
Sbjct: 1344 LGATFTVDA 1352
>XP_006710142
          Length = 671

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IGATFTVDA 9
           +GATFTVDA
Sbjct: 133 LGATFTVDA 141
>XP_006710141
          Length = 672

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IGATFTVDA 9
           +GATFTVDA
Sbjct: 133 LGATFTVDA 141
>NP_001124468
          Length = 835

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IGATFTVDA 9
           +G TFT+DA
Sbjct: 164 LGPTFTLDA 172
>NP_000850
          Length = 888

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IGATFTVDA 9
           +G TFT+DA
Sbjct: 164 LGPTFTLDA 172
>NP_003493
          Length = 862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 12 LGASFTEDA 20
>NP_851393
          Length = 826

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 12 LGASFTEDA 20
>XP_005255667
          Length = 473

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 61 LGASFTEDA 69
>XP_005255666
          Length = 862

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 12 LGASFTEDA 20
>XP_005255665
          Length = 875

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 61 LGASFTEDA 69
>XP_005255664
          Length = 911

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IGATFTVDA 9
          +GA+FT DA
Sbjct: 61 LGASFTEDA 69
>NP_001449
          Length = 2725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ATFTVD 8
            ATFTVD
Sbjct: 1174 ATFTVD 1179
>NP_001120959
          Length = 2692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ATFTVD 8
            ATFTVD
Sbjct: 1174 ATFTVD 1179
>NP_001026881
          Length = 290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IGATFTV 7
           IG TFTV
Sbjct: 260 IGGTFTV 266
>NP_001128625
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>NP_036307
          Length = 471

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IGATFT 6
           IGATFT
Sbjct: 241 IGATFT 246
>NP_208385
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IGATFT 6
           IGATFT
Sbjct: 241 IGATFT 246
>XP_005252908
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IGATFT 6
           IGATFT
Sbjct: 236 IGATFT 241
>XP_005273523
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>XP_006716387
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>XP_005273522
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>XP_005273521
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 365 IGASFTV 371
>XP_005273520
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 365 IGASFTV 371
>XP_006716386
          Length = 502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 365 IGASFTV 371
>XP_006715973
          Length = 2632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ATFTVD 8
            ATFTVD
Sbjct: 1081 ATFTVD 1086
>XP_006714955
          Length = 198

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IGATFTV 7
           IG TFTV
Sbjct: 168 IGGTFTV 174
>NP_001121903
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>NP_001128626
          Length = 481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>NP_056174
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IGATFTV 7
           IGA+FTV
Sbjct: 355 IGASFTV 361
>NP_004604
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GATFTVD 8
           G TFTV+
Sbjct: 619 GCTFTVE 625
>NP_000405
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IGATFTVD 8
           IGA +T+D
Sbjct: 660 IGAKWTID 667
>NP_001186221
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IGATFTVD 8
           IGA +T+D
Sbjct: 642 IGAKWTID 649
>NP_001186220
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IGATFTVD 8
           IGA +T+D
Sbjct: 685 IGAKWTID 692
>XP_005268801
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   IGATFTVD 8
           IGA FT D
Sbjct: 853 IGAAFTDD 860
>XP_005268800
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   IGATFTVD 8
           IGA FT D
Sbjct: 854 IGAAFTDD 861
>XP_005268799
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    IGATFTVD 8
            IGA FT D
Sbjct: 1042 IGAAFTDD 1049
>NP_056090
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    IGATFTVD 8
            IGA FT D
Sbjct: 1041 IGAAFTDD 1048
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.136    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,458
Number of extensions: 655
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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