Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              21     229
NP_001087241                                                           21     229
XP_006714101                                                           21     229
XP_005265799                                                           21     229
XP_005265798                                                           21     229
XP_005265797                                                           21     229
NP_001240813                                                           19     869
NP_079420                                                              19     869
NP_001095876                                                           19     869
XP_005263305                                                           19     869
XP_005263304                                                           19     869
XP_006714389                                                           19     869
XP_005263303                                                           19     869
XP_005263302                                                           19     869
NP_065820                                                              17    2528
NP_056009                                                              17    3301
NP_001034589                                                           17    3301
XP_006710423                                                           17    3301
NP_055437                                                              16    5631
NP_938057                                                              16    5631
NP_009156                                                              16    5631
NP_001123614                                                           16    5631
NP_001008844                                                           16    7355
NP_004406                                                              16    7355
NP_002009                                                              16    7355
NP_001258880                                                           16    7355
NP_001258881                                                           16    7355
NP_001258879                                                           16    7355
NP_001258885                                                           16    7355
NP_001258882                                                           16    7355
NP_001258878                                                           16    7355
NP_056291                                                              16    7355
NP_001258883                                                           16    7355
NP_872114                                                              16    7355
NP_006366                                                              16    7355
NP_001268665                                                           16    7355
NP_003254                                                              16    7355
NP_001243193                                                           16    7355
NP_001243194                                                           16    7355
XP_005262412                                                           16    7355
XP_005262411                                                           16    7355
XP_005258299                                                           16    7355
XP_005256615                                                           16    7355
XP_005256613                                                           16    7355
XP_005256612                                                           16    7355
XP_005262723                                                           16    7355
XP_005262722                                                           16    7355
XP_006714091                                                           16    7355
XP_005262720                                                           16    7355
XP_005262719                                                           16    7355
NP_071351                                                              15    9605
NP_065783                                                              15    9605
NP_059989                                                              15    9605
NP_001010870                                                           15    9605
NP_001161831                                                           15    9605
NP_001136336                                                           15    9605
NP_060104                                                              15    9605
XP_006721417                                                           15    9605
XP_006721416                                                           15    9605
XP_005273602                                                           15    9605
XP_005273601                                                           15    9605
XP_005273600                                                           15    9605
XP_005273599                                                           15    9605
XP_005273598                                                           15    9605
XP_006715590                                                           15    9605
XP_005267126                                                           15    9605
XP_006715589                                                           15    9605
XP_006715588                                                           15    9605
XP_006715587                                                           15    9605
XP_006715586                                                           15    9605
>NP_000213
          Length = 976

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>NP_001087241
          Length = 972

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>XP_006714101
          Length = 526

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>XP_005265799
          Length = 973

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>XP_005265798
          Length = 976

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>XP_005265797
          Length = 977

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IFLVDRSLY 9
           +FLVDRSLY
Sbjct: 117 LFLVDRSLY 125
>NP_001240813
          Length = 1166

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IFLVDRSLY 9
          +FLVDR LY
Sbjct: 33 VFLVDRFLY 41
>NP_079420
          Length = 1244

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           +FLVDR LY
Sbjct: 111 VFLVDRFLY 119
>NP_001095876
          Length = 1244

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           +FLVDR LY
Sbjct: 111 VFLVDRFLY 119
>XP_005263305
          Length = 1167

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IFLVDRSLY 9
          +FLVDR LY
Sbjct: 33 VFLVDRFLY 41
>XP_005263304
          Length = 1167

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IFLVDRSLY 9
          +FLVDR LY
Sbjct: 33 VFLVDRFLY 41
>XP_006714389
          Length = 1225

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           +FLVDR LY
Sbjct: 111 VFLVDRFLY 119
>XP_005263303
          Length = 1245

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           +FLVDR LY
Sbjct: 111 VFLVDRFLY 119
>XP_005263302
          Length = 1245

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           +FLVDR LY
Sbjct: 111 VFLVDRFLY 119
>NP_065820
          Length = 1388

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LVDRSLY 9
            L+DRSLY
Sbjct: 1300 LIDRSLY 1306
>NP_056009
          Length = 1006

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IFLVDRSLY 9
           IF+ DR LY
Sbjct: 877 IFVTDRHLY 885
>NP_001034589
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IFLVDRS 7
           IFL+DRS
Sbjct: 363 IFLIDRS 369
>XP_006710423
          Length = 932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  IFLVDRS 7
          IFL+DRS
Sbjct: 80 IFLIDRS 86
>NP_055437
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IFLVDRS 7
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_938057
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IFLVDRS 7
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_009156
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IFLVDRSLY 9
          +FLV  SLY
Sbjct: 9  VFLVQGSLY 17
>NP_001123614
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IFLVDRS 7
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_001008844
          Length = 2272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LVDRSLY 9
            L+DR LY
Sbjct: 1554 LIDRDLY 1560
>NP_004406
          Length = 2871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LVDRSLY 9
            L+DR LY
Sbjct: 2153 LIDRDLY 2159
>NP_002009
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 647 VFLLDRGL 654
>NP_001258880
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 173 IWFLDRALY 181
>NP_001258881
          Length = 179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 125 IWFLDRALY 133
>NP_001258879
          Length = 257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 130 IWFLDRALY 138
>NP_001258885
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 173 IWFLDRALY 181
>NP_001258882
          Length = 231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 173 IWFLDRALY 181
>NP_001258878
          Length = 265

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 138 IWFLDRALY 146
>NP_056291
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 173 IWFLDRALY 181
>NP_001258883
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 173 IWFLDRALY 181
>NP_872114
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FLVDRSLY 9
           ++VD++LY
Sbjct: 173 YMVDKALY 180
>NP_006366
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FLVDRSLY 9
           ++VD++LY
Sbjct: 144 YMVDKALY 151
>NP_001268665
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FLVDRSLY 9
           ++VD++LY
Sbjct: 144 YMVDKALY 151
>NP_003254
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_001243193
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 636 VFLLDRGL 643
>NP_001243194
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 592 VFLLDRGL 599
>XP_005262412
          Length = 608

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FLVDRSLY 9
           ++VD++LY
Sbjct: 173 YMVDKALY 180
>XP_005262411
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FLVDRSLY 9
           ++VD++LY
Sbjct: 173 YMVDKALY 180
>XP_005258299
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IFLVDRSLY 9
           I+ +DR+LY
Sbjct: 130 IWFLDRALY 138
>XP_005256615
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 646 VFLLDRGL 653
>XP_005256613
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 646 VFLLDRGL 653
>XP_005256612
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IFLVDRSL 8
           +FL+DR L
Sbjct: 647 VFLLDRGL 654
>XP_005262723
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262722
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_006714091
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262720
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262719
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_071351
          Length = 2752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVDRSLY 9
            +VDR+LY
Sbjct: 2245 VVDRALY 2251
>NP_065783
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1797 LFVVDRS 1803
>NP_059989
          Length = 2236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1784 LFVVDRS 1790
>NP_001010870
          Length = 2096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IFLVDR 6
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_001161831
          Length = 2066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   IFLVDR 6
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_001136336
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVDRSLY 9
            +VDR+LY
Sbjct: 2016 VVDRALY 2022
>NP_060104
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FLVDRS 7
           FL+DRS
Sbjct: 136 FLIDRS 141
>XP_006721417
          Length = 2497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVDRSLY 9
            +VDR+LY
Sbjct: 1992 VVDRALY 1998
>XP_006721416
          Length = 2504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LVDRSLY 9
            +VDR+LY
Sbjct: 1999 VVDRALY 2005
>XP_005273602
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273601
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273600
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273599
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273598
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FLVDRS 7
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_006715590
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1825 LFVVDRS 1831
>XP_005267126
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1864 LFVVDRS 1870
>XP_006715589
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1868 LFVVDRS 1874
>XP_006715588
          Length = 2330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1878 LFVVDRS 1884
>XP_006715587
          Length = 2359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1907 LFVVDRS 1913
>XP_006715586
          Length = 2373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    IFLVDRS 7
            +F+VDRS
Sbjct: 1921 LFVVDRS 1927
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.162    0.463 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 469,460
Number of extensions: 936
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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