Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060719                                                              17    2528
NP_001258968                                                           17    2528
NP_001011649                                                           17    2528
NP_001185761                                                           17    2528
NP_071754                                                              17    2528
NP_001185763                                                           17    2528
NP_001002810                                                           17    2528
NP_055459                                                              17    2528
NP_001182189                                                           17    2528
NP_001002812                                                           17    2528
NP_001182190                                                           17    2528
XP_006717248                                                           17    2528
XP_006717247                                                           17    2528
XP_006717246                                                           17    2528
XP_006717245                                                           17    2528
XP_006717244                                                           17    2528
XP_006717243                                                           17    2528
XP_006717242                                                           17    2528
XP_006711719                                                           17    2528
XP_006711717                                                           17    2528
XP_006711716                                                           17    2528
XP_006711715                                                           17    2528
XP_006711714                                                           17    2528
XP_006711713                                                           17    2528
XP_006711710                                                           17    2528
XP_006711709                                                           17    2528
NP_056110                                                              16    7355
NP_004059                                                              16    7355
NP_001020376                                                           16    7355
XP_005258159                                                           16    7355
XP_006722384                                                           16    7355
NP_597707                                                              15    9605
NP_001229858                                                           15    9605
XP_005255178                                                           15    9605
XP_005255176                                                           15    9605
>NP_060719
          Length = 1893

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>NP_001258968
          Length = 1663

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>NP_001011649
          Length = 1814

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>NP_001185761
          Length = 2240

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>NP_071754
          Length = 310

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 186 IELKVEVES 194
>NP_001185763
          Length = 2362

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>NP_001002810
          Length = 173

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>NP_055459
          Length = 2346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>NP_001182189
          Length = 141

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 17 IELKVEVES 25
>NP_001002812
          Length = 969

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>NP_001182190
          Length = 176

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 52 IELKVEVES 60
>XP_006717248
          Length = 1664

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>XP_006717247
          Length = 1670

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>XP_006717246
          Length = 1820

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>XP_006717245
          Length = 1861

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>XP_006717244
          Length = 1867

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 104 IELKVEVES 112
>XP_006717243
          Length = 1889

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 94  IELKVEVES 102
>XP_006717242
          Length = 1898

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 103 IELKVEVES 111
>XP_006711719
          Length = 2302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>XP_006711717
          Length = 2385

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>XP_006711716
          Length = 2411

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>XP_006711715
          Length = 2428

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>XP_006711714
          Length = 2429

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 49 IELKVEVES 57
>XP_006711713
          Length = 2432

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKVVVES 9
          IELKV VES
Sbjct: 52 IELKVEVES 60
>XP_006711710
          Length = 2494

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>XP_006711709
          Length = 2495

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           IELKV VES
Sbjct: 115 IELKVEVES 123
>NP_056110
          Length = 2005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           +ELKV++ S
Sbjct: 746 VELKVILHS 754
>NP_004059
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IELKVVVES 9
           +E+KVV++S
Sbjct: 301 LEVKVVIKS 309
>NP_001020376
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   IELKVVVES 9
           +E+KVV++S
Sbjct: 299 LEVKVVIKS 307
>XP_005258159
          Length = 1817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           +ELKV++ S
Sbjct: 558 VELKVILHS 566
>XP_006722384
          Length = 1877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IELKVVVES 9
           +ELKV++ S
Sbjct: 618 VELKVILHS 626
>NP_597707
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELKVVVES 9
           EL+ VVES
Sbjct: 534 ELRAVVES 541
>NP_001229858
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELKVVVES 9
           EL+ VVES
Sbjct: 427 ELRAVVES 434
>XP_005255178
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELKVVVES 9
           EL+ VVES
Sbjct: 328 ELRAVVES 335
>XP_005255176
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELKVVVES 9
           EL+ VVES
Sbjct: 405 ELRAVVES 412
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.133    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 308,687
Number of extensions: 479
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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