Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_060719                                                              18    1482
NP_001258968                                                           18    1482
NP_001011649                                                           18    1482
NP_001185761                                                           18    1482
NP_071754                                                              18    1482
NP_001185763                                                           18    1482
NP_001002810                                                           18    1482
NP_055459                                                              18    1482
NP_001182189                                                           18    1482
NP_001002812                                                           18    1482
NP_001182190                                                           18    1482
XP_006717248                                                           18    1482
XP_006717247                                                           18    1482
XP_006717246                                                           18    1482
XP_006717245                                                           18    1482
XP_006717244                                                           18    1482
XP_006717243                                                           18    1482
XP_006717242                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
NP_002649                                                              17    2528
NP_001138503                                                           17    2528
XP_006717956                                                           17    2528
NP_079390                                                              17    3301
NP_001136069                                                           17    3301
XP_006719673                                                           17    3301
XP_005269218                                                           17    3301
XP_005269217                                                           17    3301
XP_006719672                                                           17    3301
XP_005269215                                                           17    3301
XP_006718488                                                           17    3301
NP_006822                                                              17    3301
NP_001258931                                                           16    5631
NP_212132                                                              16    5631
NP_001258929                                                           16    5631
NP_001258930                                                           16    5631
NP_001258928                                                           16    5631
NP_065863                                                              16    5631
NP_001252541                                                           16    5631
NP_057368                                                              16    5631
NP_996882                                                              16    5631
XP_005260057                                                           16    5631
XP_006722865                                                           16    5631
XP_005260058                                                           16    5631
XP_005271350                                                           16    5631
XP_005271349                                                           16    5631
NP_982272                                                              16    7355
NP_001177387                                                           16    7355
NP_001180465                                                           16    7355
NP_037495                                                              16    7355
NP_001013863                                                           16    7355
NP_060190                                                              16    7355
NP_064522                                                              16    7355
XP_005272685                                                           16    7355
XP_005259649                                                           16    7355
XP_006722855                                                           16    7355
XP_006722854                                                           16    7355
XP_006722853                                                           16    7355
NP_001941                                                              16    7355
NP_060864                                                              15    9605
XP_005255684                                                           15    9605
NP_115647                                                              15    9605
>NP_060719
          Length = 1893

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>NP_001258968
          Length = 1663

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>NP_001011649
          Length = 1814

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>NP_071754
          Length = 310

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 186 IELKVEVES 194
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>NP_001002810
          Length = 173

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>NP_001182189
          Length = 141

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 17 IELKVEVES 25
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>NP_001182190
          Length = 176

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 52 IELKVEVES 60
>XP_006717248
          Length = 1664

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>XP_006717247
          Length = 1670

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>XP_006717246
          Length = 1820

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>XP_006717245
          Length = 1861

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>XP_006717244
          Length = 1867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 104 IELKVEVES 112
>XP_006717243
          Length = 1889

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 94  IELKVEVES 102
>XP_006717242
          Length = 1898

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 103 IELKVEVES 111
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 49 IELKVEVES 57
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  IELKFEVES 9
          IELK EVES
Sbjct: 52 IELKVEVES 60
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   IELKFEVES 9
           IELK EVES
Sbjct: 115 IELKVEVES 123
>NP_002649
          Length = 431

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KFEVE+
Sbjct: 251 EMKFEVEN 258
>NP_001138503
          Length = 414

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KFEVE+
Sbjct: 234 EMKFEVEN 241
>XP_006717956
          Length = 375

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KFEVE+
Sbjct: 251 EMKFEVEN 258
>NP_079390
          Length = 2479

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 2073 IELKFQLE 2080
>NP_001136069
          Length = 361

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ELKFEVES 9
          EL+FEVE+
Sbjct: 22 ELRFEVEA 29
>XP_006719673
          Length = 1997

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 1591 IELKFQLE 1598
>XP_005269218
          Length = 2009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 1603 IELKFQLE 1610
>XP_005269217
          Length = 2353

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 2104 IELKFQLE 2111
>XP_006719672
          Length = 2510

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 2104 IELKFQLE 2111
>XP_005269215
          Length = 2510

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    IELKFEVE 8
            IELKF++E
Sbjct: 2104 IELKFQLE 2111
>XP_006718488
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ELKFEVES 9
          EL+FEVE+
Sbjct: 22 ELRFEVEA 29
>NP_006822
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  ELKFEVES 9
          EL+FEVE+
Sbjct: 22 ELRFEVEA 29
>NP_001258931
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_212132
          Length = 2109

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_001258929
          Length = 2100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_001258930
          Length = 2098

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_001258928
          Length = 2129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_065863
          Length = 2047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 266 LSLKFEIE 273
>NP_001252541
          Length = 2371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IELKFEVE 8
            + LKFE+E
Sbjct: 1272 LNLKFEIE 1279
>NP_057368
          Length = 2376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IELKFEVE 8
            + LKFE+E
Sbjct: 1277 LNLKFEIE 1284
>NP_996882
          Length = 1551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IELKFEVE 8
            + LKFE+E
Sbjct: 1277 LNLKFEIE 1284
>XP_005260057
          Length = 2113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 266 LSLKFEIE 273
>XP_006722865
          Length = 2078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 266 LSLKFEIE 273
>XP_005260058
          Length = 2082

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 266 LSLKFEIE 273
>XP_005271350
          Length = 1854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>XP_005271349
          Length = 2131

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 270 LSLKFEIE 277
>NP_982272
          Length = 2099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 273 LTLKFEIE 280
>NP_001177387
          Length = 1999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 205 LTLKFEIE 212
>NP_001180465
          Length = 2031

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           + LKFE+E
Sbjct: 205 LTLKFEIE 212
>NP_037495
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IELKFE 6
           IELKFE
Sbjct: 193 IELKFE 198
>NP_001013863
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 95  EIKFKVET 102
>NP_060190
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 95  EIKFKVET 102
>NP_064522
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IELKFEVE 8
           +ELK+E+E
Sbjct: 192 VELKWEME 199
>XP_005272685
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IELKFEVE 8
           +ELK+E+E
Sbjct: 192 VELKWEME 199
>XP_005259649
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 172 EIKFKVET 179
>XP_006722855
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 172 EIKFKVET 179
>XP_006722854
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 172 EIKFKVET 179
>XP_006722853
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ELKFEVES 9
           E+KF+VE+
Sbjct: 172 EIKFKVET 179
>NP_001941
          Length = 413

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           IELK E+E
Sbjct: 98  IELKAEIE 105
>NP_060864
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IELKFEVE 8
           +ELK EVE
Sbjct: 191 VELKKEVE 198
>XP_005255684
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IELKFEV 7
           +ELKF+V
Sbjct: 331 LELKFDV 337
>NP_115647
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IELKFEV 7
           +ELKF+V
Sbjct: 333 LELKFDV 339
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.134    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 447,750
Number of extensions: 1090
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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