Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_055907                                                              19     665
XP_005255242                                                           19     665
XP_005255241                                                           19     665
XP_005255240                                                           19     665
XP_005255239                                                           19     665
NP_079414                                                              17    3301
XP_005266602                                                           17    3301
NP_004066                                                              17    4312
NP_789787                                                              17    4312
NP_001138548                                                           17    4312
NP_061936                                                              17    4312
NP_001107018                                                           17    4312
NP_001107019                                                           17    4312
NP_057441                                                              17    4312
XP_006712055                                                           17    4312
XP_006712054                                                           17    4312
XP_005264324                                                           17    4312
NP_005115                                                              16    5631
NP_001265138                                                           16    5631
NP_001265139                                                           16    5631
NP_003049                                                              16    5631
NP_001274420                                                           16    5631
NP_001248385                                                           16    5631
NP_002339                                                              16    5631
NP_001248386                                                           16    5631
XP_006715354                                                           16    5631
XP_005249564                                                           16    5631
XP_006715353                                                           16    5631
XP_006712026                                                           16    5631
XP_005264244                                                           16    5631
XP_006711388                                                           16    5631
XP_006711387                                                           16    5631
XP_006711386                                                           16    5631
XP_006711385                                                           16    5631
XP_006711384                                                           16    5631
XP_006711383                                                           16    5631
XP_005245221                                                           16    5631
NP_055935                                                              16    7355
NP_689914                                                              16    7355
NP_079146                                                              16    7355
NP_055625                                                              16    7355
NP_001171671                                                           16    7355
NP_006768                                                              16    7355
NP_065073                                                              16    7355
XP_006715582                                                           16    7355
XP_006711734                                                           16    7355
XP_006711733                                                           16    7355
XP_006711732                                                           16    7355
XP_006711731                                                           16    7355
XP_006711730                                                           16    7355
XP_006711729                                                           16    7355
XP_005245695                                                           16    7355
NP_001013375                                                           16    7355
NP_005849                                                              15    9605
NP_001026971                                                           15    9605
NP_001073908                                                           15    9605
NP_003738                                                              15    9605
NP_060864                                                              15    9605
NP_055127                                                              15    9605
NP_001103444                                                           15    9605
NP_001159681                                                           15    9605
NP_001159680                                                           15    9605
NP_009217                                                              15    9605
XP_005259763                                                           15    9605
XP_006716326                                                           15    9605
XP_005268428                                                           15    9605
XP_005268427                                                           15    9605
XP_005268426                                                           15    9605
XP_006714818                                                           15    9605
NP_619634                                                              15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IEKLSTPLN 9
           IEKLSTPL+
Sbjct: 890 IEKLSTPLD 898
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IEKLSTPLN 9
           IEKLSTPL+
Sbjct: 685 IEKLSTPLD 693
>NP_055907
          Length = 3661

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IEKLSTPLN 9
            +EKL TPLN
Sbjct: 2052 LEKLKTPLN 2060
>XP_005255242
          Length = 3609

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IEKLSTPLN 9
            +EKL TPLN
Sbjct: 2000 LEKLKTPLN 2008
>XP_005255241
          Length = 3637

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IEKLSTPLN 9
            +EKL TPLN
Sbjct: 2000 LEKLKTPLN 2008
>XP_005255240
          Length = 3663

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IEKLSTPLN 9
            +EKL TPLN
Sbjct: 2026 LEKLKTPLN 2034
>XP_005255239
          Length = 3689

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    IEKLSTPLN 9
            +EKL TPLN
Sbjct: 2052 LEKLKTPLN 2060
>NP_079414
          Length = 944

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +  LSTPLN
Sbjct: 663 LSSLSTPLN 671
>XP_005266602
          Length = 922

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +  LSTPLN
Sbjct: 641 LSSLSTPLN 649
>NP_004066
          Length = 586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IEKLSTPLN 9
           IEK +TPL+
Sbjct: 175 IEKCTTPLS 183
>NP_789787
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EKLSTPLN 9
          +KLS PLN
Sbjct: 82 QKLSEPLN 89
>NP_001138548
          Length = 923

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +EKLS P N
Sbjct: 807 VEKLSLPQN 815
>NP_061936
          Length = 981

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +EKLS P N
Sbjct: 865 VEKLSLPQN 873
>NP_001107018
          Length = 760

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           IEK + PLN
Sbjct: 187 IEKYNVPLN 195
>NP_001107019
          Length = 600

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IEKLSTPLN 9
          IEK + PLN
Sbjct: 27 IEKYNVPLN 35
>NP_057441
          Length = 759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           IEK + PLN
Sbjct: 187 IEKYNVPLN 195
>XP_006712055
          Length = 913

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +EKLS P N
Sbjct: 797 VEKLSLPQN 805
>XP_006712054
          Length = 934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +EKLS P N
Sbjct: 818 VEKLSLPQN 826
>XP_005264324
          Length = 992

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           +EKLS P N
Sbjct: 876 VEKLSLPQN 884
>NP_005115
          Length = 1475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>NP_001265138
          Length = 1506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>NP_001265139
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>NP_003049
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           ++KL  PLN
Sbjct: 547 VQKLDIPLN 555
>NP_001274420
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EKLSTP 7
            EKLSTP
Sbjct: 1179 EKLSTP 1184
>NP_001248385
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 502 EKLDTPL 508
>NP_002339
          Length = 655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 516 EKLDTPL 522
>NP_001248386
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 426 EKLDTPL 432
>XP_006715354
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>XP_005249564
          Length = 1457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>XP_006715353
          Length = 1469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IEKLSTPL 8
           +EK+S+PL
Sbjct: 315 LEKMSSPL 322
>XP_006712026
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   EKLSTP 7
           EKLSTP
Sbjct: 321 EKLSTP 326
>XP_005264244
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EKLSTP 7
            EKLSTP
Sbjct: 1179 EKLSTP 1184
>XP_006711388
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 412 EKLDTPL 418
>XP_006711387
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 412 EKLDTPL 418
>XP_006711386
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 426 EKLDTPL 432
>XP_006711385
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 502 EKLDTPL 508
>XP_006711384
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 516 EKLDTPL 522
>XP_006711383
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 502 EKLDTPL 508
>XP_005245221
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   EKLSTPL 8
           EKL TPL
Sbjct: 516 EKLDTPL 522
>NP_055935
          Length = 4169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EKLSTPLN 9
            EK+ TPL+
Sbjct: 3184 EKMKTPLS 3191
>NP_689914
          Length = 5058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    IEKLSTPLN 9
            IEK  TP N
Sbjct: 2046 IEKSETPYN 2054
>NP_079146
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    IEKLSTPLN 9
            ++KL  PLN
Sbjct: 1469 VDKLMRPLN 1477
>NP_055625
          Length = 3117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2713 EKLCTPL 2719
>NP_001171671
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKLSTPLN 9
           +KL TP+N
Sbjct: 247 QKLPTPVN 254
>NP_006768
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKLSTPLN 9
           +KL TP+N
Sbjct: 247 QKLPTPVN 254
>NP_065073
          Length = 2177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IEKLSTPL 8
           I+ LSTPL
Sbjct: 873 IDTLSTPL 880
>XP_006715582
          Length = 2106

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IEKLSTPL 8
           I+ LSTPL
Sbjct: 802 IDTLSTPL 809
>XP_006711734
          Length = 3136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2732 EKLCTPL 2738
>XP_006711733
          Length = 3137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2733 EKLCTPL 2739
>XP_006711732
          Length = 3154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2750 EKLCTPL 2756
>XP_006711731
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2753 EKLCTPL 2759
>XP_006711730
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2753 EKLCTPL 2759
>XP_006711729
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2754 EKLCTPL 2760
>XP_005245695
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    EKLSTPL 8
            EKL TPL
Sbjct: 2754 EKLCTPL 2760
>NP_001013375
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  EKLSTPL 8
          EKL+TP+
Sbjct: 53 EKLNTPM 59
>NP_005849
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKLSTPLN 9
           E LSTP N
Sbjct: 218 EPLSTPWN 225
>NP_001026971
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           ++KLSTP
Sbjct: 677 MQKLSTP 683
>NP_001073908
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  LSTPLN 9
          LSTP+N
Sbjct: 5  LSTPIN 10
>NP_003738
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           ++KL TP N
Sbjct: 819 VQKLCTPEN 827
>NP_060864
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IEKLSTPLN 9
           I+KLST +N
Sbjct: 298 IDKLSTIVN 306
>NP_055127
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  EKLSTPL 8
          E LSTPL
Sbjct: 31 EPLSTPL 37
>NP_001103444
          Length = 685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 157 IDKVSTP 163
>NP_001159681
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 401 IDKVSTP 407
>NP_001159680
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 401 IDKVSTP 407
>NP_009217
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 157 IDKVSTP 163
>XP_005259763
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKLSTPLN 9
           E LSTP N
Sbjct: 205 EPLSTPWN 212
>XP_006716326
          Length = 1316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IEKLSTPLN 9
           ++KL TP N
Sbjct: 819 VQKLCTPEN 827
>XP_005268428
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 157 IDKVSTP 163
>XP_005268427
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 157 IDKVSTP 163
>XP_005268426
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 157 IDKVSTP 163
>XP_006714818
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           I+K+STP
Sbjct: 401 IDKVSTP 407
>NP_619634
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IEKLSTP 7
           ++KLSTP
Sbjct: 138 MQKLSTP 144
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.128    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 781,159
Number of extensions: 1138
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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