Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           20     390
NP_036462                                                              20     390
NP_001243397                                                           20     390
XP_005269721                                                           20     390
NP_001092313                                                           18    1935
NP_001122405                                                           17    2528
NP_001122406                                                           17    2528
NP_001273683                                                           17    2528
NP_597734                                                              17    2528
NP_001092882                                                           17    3301
NP_006757                                                              17    3301
NP_001092883                                                           17    3301
XP_005273706                                                           17    3301
NP_057311                                                              17    4312
NP_055098                                                              17    4312
NP_001269679                                                           17    4312
XP_005245308                                                           17    4312
XP_006711439                                                           17    4312
XP_006711438                                                           17    4312
XP_006711437                                                           17    4312
NP_775873                                                              16    5631
XP_006719585                                                           16    5631
XP_006719584                                                           16    5631
XP_005269101                                                           16    5631
XP_006719583                                                           16    5631
NP_001175                                                              16    7355
NP_001269285                                                           16    7355
NP_599028                                                              16    7355
NP_439897                                                              16    7355
NP_079040                                                              16    7355
NP_064450                                                              16    7355
NP_001269286                                                           16    7355
XP_005273257                                                           16    7355
NP_001121636                                                           15    9605
NP_000323                                                              15    9605
NP_874367                                                              15    9605
NP_001277289                                                           15    9605
NP_001275993                                                           15    9605
NP_000225                                                              15    9605
NP_001275992                                                           15    9605
NP_001005463                                                           15    9605
NP_076870                                                              15    9605
NP_683692                                                              15    9605
NP_060101                                                              15    9605
XP_006723280                                                           15    9605
XP_006723279                                                           15    9605
XP_005258991                                                           15    9605
XP_006723278                                                           15    9605
XP_006717807                                                           15    9605
XP_006717806                                                           15    9605
XP_005252726                                                           15    9605
XP_006717805                                                           15    9605
XP_006717804                                                           15    9605
XP_005252725                                                           15    9605
XP_005252724                                                           15    9605
XP_006717803                                                           15    9605
XP_006717802                                                           15    9605
XP_006714890                                                           15    9605
XP_005265891                                                           15    9605
XP_005265890                                                           15    9605
XP_005248208                                                           15    9605
XP_005248207                                                           15    9605
XP_006714021                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IDSETVQAI 9
            IDSETVQA+
Sbjct: 1245 IDSETVQAV 1253
>NP_036462
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IDSETVQAI 9
            IDSETVQA+
Sbjct: 1537 IDSETVQAV 1545
>NP_001243397
          Length = 1890

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IDSETVQAI 9
            IDSETVQA+
Sbjct: 1354 IDSETVQAV 1362
>XP_005269721
          Length = 2073

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IDSETVQAI 9
            IDSETVQA+
Sbjct: 1537 IDSETVQAV 1545
>NP_001092313
          Length = 633

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           IDSE +QAI
Sbjct: 318 IDSEEIQAI 326
>NP_001122405
          Length = 1093

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IDSETVQA 8
           +DS+TVQA
Sbjct: 888 VDSDTVQA 895
>NP_001122406
          Length = 1109

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IDSETVQA 8
           +DS+TVQA
Sbjct: 888 VDSDTVQA 895
>NP_001273683
          Length = 1230

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IDSETVQA 8
           +DS+TVQA
Sbjct: 857 VDSDTVQA 864
>NP_597734
          Length = 1261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   IDSETVQA 8
           +DS+TVQA
Sbjct: 888 VDSDTVQA 895
>NP_001092882
          Length = 2004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ETVQA+
Sbjct: 1420 LDLETVQAV 1428
>NP_006757
          Length = 2004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ETVQA+
Sbjct: 1420 LDLETVQAV 1428
>NP_001092883
          Length = 2004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ETVQA+
Sbjct: 1420 LDLETVQAV 1428
>XP_005273706
          Length = 1997

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ETVQA+
Sbjct: 1413 LDLETVQAV 1421
>NP_057311
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSETV+ I
Sbjct: 283 VDSETVENI 291
>NP_055098
          Length = 1254

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSETV+ I
Sbjct: 125 VDSETVENI 133
>NP_001269679
          Length = 883

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IDSETVQAI 9
          +DSETV+ I
Sbjct: 88 VDSETVENI 96
>XP_005245308
          Length = 1092

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSETV+ I
Sbjct: 125 VDSETVENI 133
>XP_006711439
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IDSETVQAI 9
          +DSETV+ I
Sbjct: 88 VDSETVENI 96
>XP_006711438
          Length = 1217

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  IDSETVQAI 9
          +DSETV+ I
Sbjct: 88 VDSETVENI 96
>XP_006711437
          Length = 1247

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSETV+ I
Sbjct: 125 VDSETVENI 133
>NP_775873
          Length = 1576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    DSETVQA 8
            DSET+QA
Sbjct: 1409 DSETLQA 1415
>XP_006719585
          Length = 1459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    DSETVQA 8
            DSET+QA
Sbjct: 1292 DSETLQA 1298
>XP_006719584
          Length = 1515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    DSETVQA 8
            DSET+QA
Sbjct: 1348 DSETLQA 1354
>XP_005269101
          Length = 1577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    DSETVQA 8
            DSET+QA
Sbjct: 1410 DSETLQA 1416
>XP_006719583
          Length = 1586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    DSETVQA 8
            DSET+QA
Sbjct: 1419 DSETLQA 1425
>NP_001175
          Length = 2644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DSETVQAI 9
            DSETV+ I
Sbjct: 1324 DSETVEPI 1331
>NP_001269285
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSET+Q +
Sbjct: 494 MDSETLQQV 502
>NP_599028
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSET+Q +
Sbjct: 494 MDSETLQQV 502
>NP_439897
          Length = 656

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSET+Q +
Sbjct: 494 MDSETLQQV 502
>NP_079040
          Length = 1116

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DS+ VQA+
Sbjct: 640 LDSQVVQAL 648
>NP_064450
          Length = 1722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ET+QA+
Sbjct: 1394 VDLETLQAL 1402
>NP_001269286
          Length = 355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDSETVQAI 9
           +DSET+Q +
Sbjct: 193 MDSETLQQV 201
>XP_005273257
          Length = 1726

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D ET+QA+
Sbjct: 1398 VDLETLQAL 1406
>NP_001121636
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS TV+ I
Sbjct: 610 IDSSTVERI 618
>NP_000323
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS TV+ I
Sbjct: 610 IDSSTVERI 618
>NP_874367
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>NP_001277289
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>NP_001275993
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 718 DSEELQAI 725
>NP_000225
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 786 DSEELQAI 793
>NP_001275992
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 755 DSEELQAI 762
>NP_001005463
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>NP_076870
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>NP_683692
          Length = 3051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    IDSETV 6
            IDSETV
Sbjct: 1233 IDSETV 1238
>NP_060101
          Length = 1712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    IDSETVQAI 9
            +D+ET+Q +
Sbjct: 1232 VDTETLQKV 1240
>XP_006723280
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 380 DSEELQAI 387
>XP_006723279
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 786 DSEELQAI 793
>XP_005258991
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 756 DSEELQAI 763
>XP_006723278
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DSETVQAI 9
           DSE +QAI
Sbjct: 785 DSEELQAI 792
>XP_006717807
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006717806
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_005252726
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006717805
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006717804
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_005252725
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_005252724
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006717803
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006717802
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_006714890
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 93  IDSMTKQAI 101
>XP_005265891
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_005265890
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IDSETVQAI 9
           IDS T QAI
Sbjct: 131 IDSMTKQAI 139
>XP_005248208
          Length = 3097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    IDSETV 6
            IDSETV
Sbjct: 1233 IDSETV 1238
>XP_005248207
          Length = 3098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    IDSETV 6
            IDSETV
Sbjct: 1233 IDSETV 1238
>XP_006714021
          Length = 3112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    IDSETV 6
            IDSETV
Sbjct: 1233 IDSETV 1238
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.122    0.282 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,535
Number of extensions: 594
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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