Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     665
XP_005273257                                                           19     665
NP_115627                                                              17    2528
XP_006718583                                                           17    2528
XP_006718582                                                           17    2528
NP_006273                                                              16    5631
NP_060500                                                              16    5631
NP_001229437                                                           16    5631
NP_542164                                                              16    5631
XP_005260590                                                           16    5631
XP_006723933                                                           16    5631
XP_005260589                                                           16    5631
XP_005260588                                                           16    5631
XP_005260587                                                           16    5631
XP_006722446                                                           16    5631
XP_006722445                                                           16    5631
XP_006722444                                                           16    5631
XP_006722443                                                           16    5631
NP_065801                                                              16    7355
NP_219493                                                              16    7355
NP_001033043                                                           16    7355
XP_005254804                                                           16    7355
XP_006720791                                                           16    7355
XP_005254803                                                           16    7355
XP_005254800                                                           16    7355
XP_005254799                                                           16    7355
XP_005277785                                                           16    7355
XP_005277784                                                           16    7355
XP_005277783                                                           16    7355
NP_003913                                                              16    7355
NP_001138830                                                           15    9605
NP_001138829                                                           15    9605
NP_056292                                                              15    9605
NP_065207                                                              15    9605
NP_001258029                                                           15    9605
NP_001129505                                                           15    9605
NP_055096                                                              15    9605
NP_008949                                                              15    9605
NP_510965                                                              15    9605
NP_001258028                                                           15    9605
NP_001258026                                                           15    9605
NP_001660                                                              15    9605
NP_001258025                                                           15    9605
NP_001258027                                                           15    9605
XP_005274573                                                           15    9605
XP_005274572                                                           15    9605
XP_005274571                                                           15    9605
XP_005258296                                                           15    9605
XP_006720530                                                           15    9605
XP_006720529                                                           15    9605
XP_006720528                                                           15    9605
XP_005268640                                                           15    9605
XP_006717006                                                           15    9605
XP_006717005                                                           15    9605
XP_006717004                                                           15    9605
XP_006717003                                                           15    9605
XP_005251736                                                           15    9605
NP_006829                                                              15    9605
>NP_064450
          Length = 1722

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IDQAAEENS 9
            IDQ AEENS
Sbjct: 1622 IDQEAEENS 1630
>XP_005273257
          Length = 1726

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IDQAAEENS 9
            IDQ AEENS
Sbjct: 1626 IDQEAEENS 1634
>NP_115627
          Length = 1476

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ AEEN
Sbjct: 412 VDQLAEEN 419
>XP_006718583
          Length = 1482

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ AEEN
Sbjct: 334 VDQLAEEN 341
>XP_006718582
          Length = 1560

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ AEEN
Sbjct: 412 VDQLAEEN 419
>NP_006273
          Length = 487

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 312 VDQDDEENS 320
>NP_060500
          Length = 437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 373 IDQASEE 379
>NP_001229437
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 504 IDQASEE 510
>NP_542164
          Length = 950

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 886 IDQASEE 892
>XP_005260590
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 312 VDQDDEENS 320
>XP_006723933
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 299 VDQDDEENS 307
>XP_005260589
          Length = 474

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 299 VDQDDEENS 307
>XP_005260588
          Length = 478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 328 VDQDDEENS 336
>XP_005260587
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IDQAAEENS 9
           +DQ  EENS
Sbjct: 328 VDQDDEENS 336
>XP_006722446
          Length = 889

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 825 IDQASEE 831
>XP_006722445
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 841 IDQASEE 847
>XP_006722444
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 850 IDQASEE 856
>XP_006722443
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           IDQA+EE
Sbjct: 861 IDQASEE 867
>NP_065801
          Length = 1204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DQAAEEN 8
           D+AA+EN
Sbjct: 944 DEAADEN 950
>NP_219493
          Length = 472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ+ EEN
Sbjct: 132 LDQSMEEN 139
>NP_001033043
          Length = 683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ+ EEN
Sbjct: 343 LDQSMEEN 350
>XP_005254804
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2552 IDQQAEES 2559
>XP_006720791
          Length = 4853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2609 IDQQAEES 2616
>XP_005254803
          Length = 4854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2617 IDQQAEES 2624
>XP_005254800
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2617 IDQQAEES 2624
>XP_005254799
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2617 IDQQAEES 2624
>XP_005277785
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ+ EEN
Sbjct: 132 LDQSMEEN 139
>XP_005277784
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ+ EEN
Sbjct: 342 LDQSMEEN 349
>XP_005277783
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IDQAAEEN 8
           +DQ+ EEN
Sbjct: 343 LDQSMEEN 350
>NP_003913
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    IDQAAEEN 8
            IDQ AEE+
Sbjct: 2617 IDQQAEES 2624
>NP_001138830
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>NP_001138829
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>NP_056292
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>NP_065207
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDQAAEENS 9
           +D+A EE+S
Sbjct: 524 LDKATEEDS 532
>NP_001258029
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 155 IDQLAEE 161
>NP_001129505
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 172 IDQLAEE 178
>NP_055096
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 198 IDQLAEE 204
>NP_008949
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1812 AAEENS 1817
>NP_510965
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 215 IDQLAEE 221
>NP_001258028
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 186 IDQLAEE 192
>NP_001258026
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 169 IDQLAEE 175
>NP_001660
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IDQAAEE 7
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>NP_001258025
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 197 IDQLAEE 203
>NP_001258027
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   IDQAAEE 7
           IDQ AEE
Sbjct: 214 IDQLAEE 220
>XP_005274573
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IDQAAEE 7
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005274572
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IDQAAEE 7
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005274571
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IDQAAEE 7
          IDQ AEE
Sbjct: 69 IDQLAEE 75
>XP_005258296
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IDQAAEENS 9
           +D+A EE+S
Sbjct: 524 LDKATEEDS 532
>XP_006720530
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>XP_006720529
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>XP_006720528
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DQAAEENS 9
           +QA EEN+
Sbjct: 762 EQATEENA 769
>XP_005268640
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           +DQA+EE
Sbjct: 157 LDQASEE 163
>XP_006717006
          Length = 1760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1232 AAEENS 1237
>XP_006717005
          Length = 1788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1260 AAEENS 1265
>XP_006717004
          Length = 2240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1812 AAEENS 1817
>XP_006717003
          Length = 2278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1812 AAEENS 1817
>XP_005251736
          Length = 2325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AAEENS 9
            AAEENS
Sbjct: 1812 AAEENS 1817
>NP_006829
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IDQAAEE 7
           +DQA+EE
Sbjct: 158 LDQASEE 164
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.284    0.105    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,344
Number of extensions: 894
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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