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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           17    3301
NP_000170                                                              17    3301
NP_001268422                                                           17    3301
NP_001268423                                                           17    3301
XP_005264328                                                           17    3301
NP_598397                                                              17    4312
NP_004728                                                              17    4312
XP_006724438                                                           17    4312
XP_005261889                                                           17    4312
XP_005261888                                                           17    4312
NP_001278383                                                           16    5631
NP_055676                                                              16    5631
NP_001273456                                                           16    5631
XP_006721418                                                           16    5631
XP_005265151                                                           16    5631
NP_055362                                                              15    9605
XP_006720542                                                           15    9605

>NP_001268421
          Length = 1230

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    IANAVVKK 8
            IANAVVK+
Sbjct: 1097 IANAVVKE 1104



>NP_000170
          Length = 1360

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    IANAVVKK 8
            IANAVVK+
Sbjct: 1227 IANAVVKE 1234



>NP_001268422
          Length = 1058

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   IANAVVKK 8
           IANAVVK+
Sbjct: 925 IANAVVKE 932



>NP_001268423
          Length = 1058

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   IANAVVKK 8
           IANAVVK+
Sbjct: 925 IANAVVKE 932



>XP_005264328
          Length = 1261

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    IANAVVKK 8
            IANAVVK+
Sbjct: 1128 IANAVVKE 1135



>NP_598397
          Length = 756

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IANAVVKKN 9
           I NAV+K+N
Sbjct: 337 IFNAVIKQN 345



>NP_004728
          Length = 756

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IANAVVKKN 9
           I NAV+K+N
Sbjct: 337 IFNAVIKQN 345



>XP_006724438
          Length = 577

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IANAVVKKN 9
           I NAV+K+N
Sbjct: 337 IFNAVIKQN 345



>XP_005261889
          Length = 756

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IANAVVKKN 9
           I NAV+K+N
Sbjct: 337 IFNAVIKQN 345



>XP_005261888
          Length = 756

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   IANAVVKKN 9
           I NAV+K+N
Sbjct: 337 IFNAVIKQN 345



>NP_001278383
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAVVKKN 9
           NAV++KN
Sbjct: 293 NAVIRKN 299



>NP_055676
          Length = 946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAVVKKN 9
           NAV++KN
Sbjct: 444 NAVIRKN 450



>NP_001273456
          Length = 975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAVVKKN 9
           NAV++KN
Sbjct: 444 NAVIRKN 450



>XP_006721418
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NAVVKKN 9
           NAV++KN
Sbjct: 444 NAVIRKN 450



>XP_005265151
          Length = 2058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IANAVVKKN 9
            I+N V+KKN
Sbjct: 2043 ISNFVLKKN 2051



>NP_055362
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ANAVVKKN 9
           ANA+ K N
Sbjct: 332 ANAITKNN 339



>XP_006720542
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ANAVVKKN 9
           ANA+ K N
Sbjct: 332 ANAITKNN 339



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.120    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 310,715
Number of extensions: 330
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)