Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              18    1935
NP_001075109                                                           18    1935
NP_722541                                                              17    3301
NP_001092140                                                           17    3301
NP_001092141                                                           17    3301
XP_006718478                                                           17    3301
XP_006718477                                                           17    3301
XP_006718476                                                           17    3301
XP_006718475                                                           17    3301
XP_005273764                                                           17    3301
XP_006718474                                                           17    3301
NP_064541                                                              16    7355
XP_006715822                                                           16    7355
XP_005249870                                                           16    7355
XP_005249869                                                           16    7355
NP_001026                                                              15    9605
XP_006711873                                                           15    9605
XP_006711871                                                           15    9605
XP_006711870                                                           15    9605
XP_006711869                                                           15    9605
XP_006711868                                                           15    9605
XP_006711867                                                           15    9605
XP_006711866                                                           15    9605
XP_006711865                                                           15    9605
>NP_008835
          Length = 4128

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            IAKQLFS L
Sbjct: 2804 IAKQLFSSL 2812
>NP_001075109
          Length = 4097

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            IAKQLFS L
Sbjct: 2804 IAKQLFSSL 2812
>NP_722541
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 335 KQLFSIL 341
>NP_001092140
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 335 KQLFSIL 341
>NP_001092141
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 335 KQLFSIL 341
>XP_006718478
          Length = 464

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 190 KQLFSIL 196
>XP_006718477
          Length = 464

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 190 KQLFSIL 196
>XP_006718476
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 335 KQLFSIL 341
>XP_006718475
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 335 KQLFSIL 341
>XP_005273764
          Length = 668

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 394 KQLFSIL 400
>XP_006718474
          Length = 897

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   KQLFSIL 9
           KQLFSIL
Sbjct: 623 KQLFSIL 629
>NP_064541
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAKQLFSIL 9
          +  QLFSIL
Sbjct: 22 LCSQLFSIL 30
>XP_006715822
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAKQLFSIL 9
          +  QLFSIL
Sbjct: 22 LCSQLFSIL 30
>XP_005249870
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAKQLFSIL 9
          +  QLFSIL
Sbjct: 22 LCSQLFSIL 30
>XP_005249869
          Length = 371

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAKQLFSIL 9
          +  QLFSIL
Sbjct: 30 LCSQLFSIL 38
>NP_001026
          Length = 4967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3912 VAKQVFNTL 3920
>XP_006711873
          Length = 4954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3899 VAKQVFNTL 3907
>XP_006711871
          Length = 4906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3851 VAKQVFNTL 3859
>XP_006711870
          Length = 4965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3910 VAKQVFNTL 3918
>XP_006711869
          Length = 4973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3918 VAKQVFNTL 3926
>XP_006711868
          Length = 4975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3920 VAKQVFNTL 3928
>XP_006711867
          Length = 4977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3922 VAKQVFNTL 3930
>XP_006711866
          Length = 4984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3929 VAKQVFNTL 3937
>XP_006711865
          Length = 4985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    IAKQLFSIL 9
            +AKQ+F+ L
Sbjct: 3930 VAKQVFNTL 3938
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.150    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,444
Number of extensions: 357
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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