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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_078809                                                              18    1135
NP_067628                                                              18    1135
XP_005256012                                                           18    1135
NP_788954                                                              17    3301
XP_006710662                                                           17    3301
XP_006718174                                                           17    4312
XP_006710007                                                           17    4312
NP_001259004                                                           16    5631
NP_005144                                                              16    5631
XP_006721395                                                           16    5631
XP_006721394                                                           16    5631
XP_006721393                                                           16    5631
NP_694590                                                              16    7355
NP_001106197                                                           16    7355
NP_055820                                                              16    7355
NP_004764                                                              16    7355
XP_005267607                                                           16    7355
XP_005251848                                                           16    7355
XP_006717060                                                           16    7355
XP_005251847                                                           16    7355
XP_005251846                                                           16    7355
NP_004855                                                              15    9605
NP_001157570                                                           15    9605
NP_004376                                                              15    9605

>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4187 IAESAALRP 4195



>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4203 IAESAALRP 4211



>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4204 IAESAALRP 4212



>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4235 IAESAALRP 4243



>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4259 IAESAALRP 4267



>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4258 IAESAALRP 4266



>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4258 IAESAALRP 4266



>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4258 IAESAALRP 4266



>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    IAESATLRP 9
            IAESA LRP
Sbjct: 4259 IAESAALRP 4267



>NP_078809
          Length = 411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IAESATLRP 9
           IAE+ATL+P
Sbjct: 274 IAEAATLKP 282



>NP_067628
          Length = 395

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IAESATLRP 9
           IAE+ATL+P
Sbjct: 252 IAEAATLKP 260



>XP_005256012
          Length = 395

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   IAESATLRP 9
           IAE+ATL+P
Sbjct: 252 IAEAATLKP 260



>NP_788954
          Length = 585

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IAESATLRP 9
           IAE A LRP
Sbjct: 415 IAEPAALRP 423



>XP_006710662
          Length = 559

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   IAESATLRP 9
           IAE A LRP
Sbjct: 389 IAEPAALRP 397



>XP_006718174
          Length = 427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ESATLRP 9
          +SATLRP
Sbjct: 64 QSATLRP 70



>XP_006710007
          Length = 348

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ESATLRP 9
          +SATLRP
Sbjct: 64 QSATLRP 70



>NP_001259004
          Length = 802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESATLRP 9
           ESATL+P
Sbjct: 625 ESATLQP 631



>NP_005144
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESATLRP 9
           ESATL+P
Sbjct: 621 ESATLQP 627



>XP_006721395
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESATLRP 9
           ESATL+P
Sbjct: 425 ESATLQP 431



>XP_006721394
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESATLRP 9
           ESATL+P
Sbjct: 626 ESATLQP 632



>XP_006721393
          Length = 781

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ESATLRP 9
           ESATL+P
Sbjct: 626 ESATLQP 632



>NP_694590
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAESATLRP 9
          +AESA L P
Sbjct: 81 LAESALLEP 89



>NP_001106197
          Length = 1554

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AESATLRP 9
           A SAT RP
Sbjct: 603 ASSATFRP 610



>NP_055820
          Length = 1519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AESATLRP 9
           A SAT RP
Sbjct: 533 ASSATFRP 540



>NP_004764
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IAESATLR 8
           + ESATLR
Sbjct: 95  LGESATLR 102



>XP_005267607
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AESATLRP 9
           A SAT RP
Sbjct: 603 ASSATFRP 610



>XP_005251848
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IAESATLRP 9
           +AESA L P
Sbjct: 108 LAESALLEP 116



>XP_006717060
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  IAESATLRP 9
          +AESA L P
Sbjct: 82 LAESALLEP 90



>XP_005251847
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IAESATLRP 9
           +AESA L P
Sbjct: 107 LAESALLEP 115



>XP_005251846
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   IAESATLRP 9
           +AESA L P
Sbjct: 108 LAESALLEP 116



>NP_004855
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IAESATLRP 9
           +AES++ RP
Sbjct: 170 LAESSSARP 178



>NP_001157570
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IAESATLR 8
           IAE +TLR
Sbjct: 891 IAEKSTLR 898



>NP_004376
          Length = 3396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IAESATLR 8
           IAE +TLR
Sbjct: 891 IAEKSTLR 898



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.122    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 280,494
Number of extensions: 264
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)