Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1135
NP_444254                                                              18    1135
NP_444253                                                              18    1135
NP_444255                                                              18    1135
XP_005247551                                                           18    1135
XP_005247550                                                           18    1135
XP_006713712                                                           18    1135
XP_005247549                                                           18    1135
NP_001165405                                                           15    9605
NP_001165404                                                           15    9605
NP_071407                                                              15    9605
NP_001185771                                                           15    9605
XP_006726484                                                           15    9605
XP_005266585                                                           15    9605
XP_006718005                                                           15    9605
XP_006718004                                                           15    9605
XP_006718003                                                           15    9605
XP_006715006                                                           15    9605
XP_005275746                                                           15    9605
XP_003403671                                                           15    9605
XP_006710003                                                           15    9605
XP_006710234                                                           15    9605
NP_006422                                                              15    9605
>NP_444256
          Length = 1794

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 394 VVSKAANR 401
>NP_444254
          Length = 1845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 394 VVSKAANR 401
>NP_444253
          Length = 1914

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 394 VVSKAANR 401
>NP_444255
          Length = 1863

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 394 VVSKAANR 401
>XP_005247551
          Length = 1855

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 404 VVSKAANR 411
>XP_005247550
          Length = 1856

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 404 VVSKAANR 411
>XP_006713712
          Length = 1923

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 404 VVSKAANR 411
>XP_005247549
          Length = 1924

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VVSKAANR 9
           VVSKAANR
Sbjct: 404 VVSKAANR 411
>NP_001165405
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVVSKAANR 9
           HVV++  NR
Sbjct: 772 HVVNRDTNR 780
>NP_001165404
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVVSKAANR 9
           HVV++  NR
Sbjct: 772 HVVNRDTNR 780
>NP_071407
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3012 HVVNRDTNR 3020
>NP_001185771
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVVSKAANR 9
           H V++ ANR
Sbjct: 372 HAVTQLANR 380
>XP_006726484
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HVVSKA 6
          H+VSKA
Sbjct: 64 HIVSKA 69
>XP_005266585
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HVVSKAAN 8
           H+V KAA+
Sbjct: 208 HIVCKAAS 215
>XP_006718005
          Length = 3397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3055 HVVNRDTNR 3063
>XP_006718004
          Length = 3399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3057 HVVNRDTNR 3065
>XP_006718003
          Length = 3419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3077 HVVNRDTNR 3085
>XP_006715006
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HVVSKA 6
          H+VSKA
Sbjct: 64 HIVSKA 69
>XP_005275746
          Length = 3352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3010 HVVNRDTNR 3018
>XP_003403671
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3012 HVVNRDTNR 3020
>XP_006710003
          Length = 3374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVVSKAANR 9
            HVV++  NR
Sbjct: 3032 HVVNRDTNR 3040
>XP_006710234
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HVVSKA 6
          H+VSKA
Sbjct: 64 HIVSKA 69
>NP_006422
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVVSKAANR 9
           H V++ ANR
Sbjct: 419 HAVTQLANR 427
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.115    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 225,308
Number of extensions: 256
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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