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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              21     175
XP_005262424                                                           21     175
NP_003632                                                              17    2528
NP_003706                                                              17    4312
NP_001276978                                                           17    4312
NP_004520                                                              17    4312
NP_001273620                                                           17    4312
XP_006714460                                                           17    4312
XP_006714459                                                           17    4312
NP_997244                                                              16    5631
XP_006720419                                                           16    5631
NP_001275701                                                           16    7355
NP_004561                                                              16    7355
NP_064613                                                              16    7355
NP_001275703                                                           16    7355
NP_061738                                                              16    7355
NP_114398                                                              16    7355
XP_005253450                                                           16    7355
XP_006719151                                                           16    7355
NP_955469                                                              16    7355
NP_955471                                                              16    7355
NP_955470                                                              16    7355
NP_064627                                                              15    9605
NP_001272415                                                           15    9605
NP_061736                                                              15    9605
XP_006713328                                                           15    9605
XP_006713327                                                           15    9605
XP_006713326                                                           15    9605
XP_006713325                                                           15    9605
XP_006713324                                                           15    9605
XP_005265385                                                           15    9605
NP_114479                                                              15    9605

>NP_722576
          Length = 3080

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HVMLQIINI 9
            HVMLQIIN+
Sbjct: 2512 HVMLQIINV 2520



>XP_005262424
          Length = 2875

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HVMLQIINI 9
            HVMLQIIN+
Sbjct: 2307 HVMLQIINV 2315



>NP_003632
          Length = 125

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HVMLQII 7
           H+MLQII
Sbjct: 113 HIMLQII 119



>NP_003706
          Length = 962

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H+MLQ++ +
Sbjct: 281 HLMLQLVRV 289



>NP_001276978
          Length = 973

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H+MLQ++ +
Sbjct: 285 HLMLQLVRV 293



>NP_004520
          Length = 568

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H++ QI+N+
Sbjct: 521 HILQQIVNL 529



>NP_001273620
          Length = 565

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H++ QI+N+
Sbjct: 518 HILQQIVNL 526



>XP_006714460
          Length = 966

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H+MLQ++ +
Sbjct: 285 HLMLQLVRV 293



>XP_006714459
          Length = 969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H+MLQ++ +
Sbjct: 281 HLMLQLVRV 289



>NP_997244
          Length = 3169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    HVMLQIIN 8
            H+M Q+IN
Sbjct: 1237 HIMNQLIN 1244



>XP_006720419
          Length = 138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   MLQIINI 9
           MLQ++NI
Sbjct: 96  MLQVVNI 102



>NP_001275701
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVMLQIINI 9
            H M QI+N+
Sbjct: 1323 HYMEQILNV 1331



>NP_004561
          Length = 1445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVMLQIINI 9
            H M QI+N+
Sbjct: 1282 HYMEQILNV 1290



>NP_064613
          Length = 1160

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H+ LQ++ +
Sbjct: 941 HIQLQVVQV 949



>NP_001275703
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVMLQIINI 9
            H M QI+N+
Sbjct: 1101 HYMEQILNV 1109



>NP_061738
          Length = 932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H++LQ+ +I
Sbjct: 437 HILLQVADI 445



>NP_114398
          Length = 823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HVMLQIINI 9
           H++LQ+ +I
Sbjct: 437 HILLQVADI 445



>XP_005253450
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVMLQIINI 9
            H M QI+N+
Sbjct: 1323 HYMEQILNV 1331



>XP_006719151
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HVMLQIINI 9
            H M QI+N+
Sbjct: 1323 HYMEQILNV 1331



>NP_955469
          Length = 1156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H+ LQ++ +
Sbjct: 937 HIQLQVVQV 945



>NP_955471
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H+ LQ++ +
Sbjct: 851 HIQLQVVQV 859



>NP_955470
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H+ LQ++ +
Sbjct: 855 HIQLQVVQV 863



>NP_064627
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 841 HVQLQLDNL 849



>NP_001272415
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  HVMLQII 7
          H++LQI+
Sbjct: 90 HILLQIL 96



>NP_061736
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H MLQ+ +I
Sbjct: 441 HFMLQVADI 449



>XP_006713328
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 841 HVQLQLDNL 849



>XP_006713327
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 476 HVQLQLDNL 484



>XP_006713326
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 841 HVQLQLDNL 849



>XP_006713325
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 841 HVQLQLDNL 849



>XP_006713324
          Length = 1285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 841 HVQLQLDNL 849



>XP_005265385
          Length = 1291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           HV LQ+ N+
Sbjct: 744 HVQLQLDNL 752



>NP_114479
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HVMLQIINI 9
           H MLQ+ +I
Sbjct: 441 HFMLQVADI 449



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.153    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,461
Number of extensions: 668
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)