Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001275701                                                           20     390
NP_004561                                                              20     390
NP_001275703                                                           20     390
XP_005253450                                                           20     390
XP_006719151                                                           20     390
NP_067636                                                              17    4312
NP_078789                                                              16    5631
NP_001092261                                                           16    5631
NP_067065                                                              16    5631
NP_714544                                                              16    5631
XP_005265541                                                           16    5631
XP_006713398                                                           16    5631
XP_006713397                                                           16    5631
XP_006713396                                                           16    5631
NP_001092260                                                           16    5631
NP_066988                                                              16    7355
NP_001139190                                                           16    7355
NP_000928                                                              16    7355
NP_001171663                                                           16    7355
NP_937831                                                              16    7355
NP_937830                                                              16    7355
NP_937829                                                              16    7355
NP_054729                                                              16    7355
XP_006719245                                                           16    7355
XP_006719244                                                           16    7355
XP_005245436                                                           16    7355
NP_060848                                                              16    7355
NP_005471                                                              16    7355
NP_001121650                                                           15    9605
NP_997064                                                              15    9605
NP_000263                                                              15    9605
NP_620482                                                              15    9605
NP_001077084                                                           15    9605
NP_001276024                                                           15    9605
NP_001229269                                                           15    9605
NP_776168                                                              15    9605
NP_001124429                                                           15    9605
NP_444282                                                              15    9605
NP_001005161                                                           15    9605
NP_001171661                                                           15    9605
NP_004245                                                              15    9605
NP_001171665                                                           15    9605
NP_001171662                                                           15    9605
NP_001166127                                                           15    9605
NP_066023                                                              15    9605
XP_005273812                                                           15    9605
XP_006713966                                                           15    9605
XP_006713965                                                           15    9605
XP_006713964                                                           15    9605
XP_006713963                                                           15    9605
XP_006712615                                                           15    9605
XP_005263736                                                           15    9605
XP_005263735                                                           15    9605
XP_005263734                                                           15    9605
XP_005263733                                                           15    9605
XP_005263732                                                           15    9605
XP_006712614                                                           15    9605
XP_006712362                                                           15    9605
XP_006711820                                                           15    9605
XP_005273147                                                           15    9605
NP_001166130                                                           15    9605
>NP_001275701
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTILRRLTF 9
           HTILRR TF
Sbjct: 751 HTILRRWTF 759
>NP_004561
          Length = 1445

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTILRRLTF 9
           HTILRR TF
Sbjct: 710 HTILRRWTF 718
>NP_001275703
          Length = 1264

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTILRRLTF 9
           HTILRR TF
Sbjct: 529 HTILRRWTF 537
>XP_005253450
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTILRRLTF 9
           HTILRR TF
Sbjct: 751 HTILRRWTF 759
>XP_006719151
          Length = 1486

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTILRRLTF 9
           HTILRR TF
Sbjct: 751 HTILRRWTF 759
>NP_067636
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HTILRR 6
           HTILRR
Sbjct: 176 HTILRR 181
>NP_078789
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           HT LRRL
Sbjct: 334 HTALRRL 340
>NP_001092261
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTILRRLT 8
           HT+L +LT
Sbjct: 155 HTVLSKLT 162
>NP_067065
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTILRRLT 8
           HT+L +LT
Sbjct: 155 HTVLSKLT 162
>NP_714544
          Length = 1775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           H +LR LTF
Sbjct: 621 HYLLRLLTF 629
>XP_005265541
          Length = 1080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           HT LRRL
Sbjct: 334 HTALRRL 340
>XP_006713398
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           HT LRRL
Sbjct: 334 HTALRRL 340
>XP_006713397
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           HT LRRL
Sbjct: 334 HTALRRL 340
>XP_006713396
          Length = 1478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           HT LRRL
Sbjct: 334 HTALRRL 340
>NP_001092260
          Length = 183

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTILRRLT 8
           HT+L +LT
Sbjct: 155 HTVLSKLT 162
>NP_066988
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 387 HRILRRL 393
>NP_001139190
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           H++LRRL
Sbjct: 129 HSLLRRL 135
>NP_000928
          Length = 1970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    HTILRRLT 8
            HT LR++T
Sbjct: 1163 HTTLRKVT 1170
>NP_001171663
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 316 HLILRRL 322
>NP_937831
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 316 HLILRRL 322
>NP_937830
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 316 HLILRRL 322
>NP_937829
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 365 HLILRRL 371
>NP_054729
          Length = 1288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    HTILRRL 7
            H ILRRL
Sbjct: 1213 HLILRRL 1219
>XP_006719245
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HTILRRLT 8
           +++LRRLT
Sbjct: 343 YSVLRRLT 350
>XP_006719244
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HTILRRLT 8
           +++LRRLT
Sbjct: 343 YSVLRRLT 350
>XP_005245436
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HTILRRL 7
           H ILRRL
Sbjct: 387 HRILRRL 393
>NP_060848
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           H  LRRL+F
Sbjct: 139 HLDLRRLSF 147
>NP_005471
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HTILRRLT 8
           +++LRRLT
Sbjct: 343 YSVLRRLT 350
>NP_001121650
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>NP_997064
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>NP_000263
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>NP_620482
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           H I++ LTF
Sbjct: 447 HLIVQHLTF 455
>NP_001077084
          Length = 1314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           H I++ LTF
Sbjct: 447 HLIVQHLTF 455
>NP_001276024
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HTILRR 6
          HTI+RR
Sbjct: 33 HTIVRR 38
>NP_001229269
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  HTILRRLTF 9
          HT+L+R  +
Sbjct: 11 HTVLKRKVY 19
>NP_776168
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           HT+L+R  +
Sbjct: 162 HTVLKRKVY 170
>NP_001124429
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           HT+L+R  +
Sbjct: 162 HTVLKRKVY 170
>NP_444282
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRRL+F
Sbjct: 559 VLRRLSF 565
>NP_001005161
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +L+RLTF
Sbjct: 164 LLKRLTF 170
>NP_001171661
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRR+TF
Sbjct: 322 MLRRMTF 328
>NP_004245
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRR+TF
Sbjct: 322 MLRRMTF 328
>NP_001171665
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRR+TF
Sbjct: 199 MLRRMTF 205
>NP_001171662
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRR+TF
Sbjct: 231 MLRRMTF 237
>NP_001166127
          Length = 857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 231 HTLLRKI 237
>NP_066023
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 261 HTLLRKI 267
>XP_005273812
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILRRLTF 9
           +LRRL+F
Sbjct: 428 VLRRLSF 434
>XP_006713966
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 261 HTLLRKI 267
>XP_006713965
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 261 HTLLRKI 267
>XP_006713964
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 231 HTLLRKI 237
>XP_006713963
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 261 HTLLRKI 267
>XP_006712615
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_005263736
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_005263735
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_005263734
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_005263733
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_005263732
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_006712614
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTILRRLT 8
          HT+L +LT
Sbjct: 86 HTLLDKLT 93
>XP_006712362
          Length = 1350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTILRRLTF 9
           H I++ LTF
Sbjct: 456 HLIVQHLTF 464
>XP_006711820
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  HTILRRLTF 9
          HT+L+R  +
Sbjct: 20 HTVLKRKVY 28
>XP_005273147
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  HTILRRLTF 9
          HT+L+R  +
Sbjct: 20 HTVLKRKVY 28
>NP_001166130
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HTILRRL 7
           HT+LR++
Sbjct: 191 HTLLRKI 197
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.351    0.154    0.473 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 456,057
Number of extensions: 806
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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