Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_071504                                                              16    5631
NP_000911                                                              16    5631
NP_001035806                                                           16    5631
XP_006718641                                                           16    5631
XP_005274089                                                           16    5631
XP_005274088                                                           16    5631
XP_006718640                                                           16    5631
NP_000341                                                              16    7355
NP_001004450                                                           16    7355
NP_001171486                                                           15    9605
NP_001171487                                                           15    9605
XP_005246752                                                           15    9605
XP_005246751                                                           15    9605
XP_006712706                                                           15    9605
XP_006712705                                                           15    9605
XP_006712704                                                           15    9605
XP_005246750                                                           15    9605
NP_071341                                                              15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 598 TDSLLIAV 605
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 598 TDSLLIAV 605
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TDSLLIAV
Sbjct: 599 TDSLLIAV 606
>NP_071504
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>NP_000911
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>NP_001035806
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>XP_006718641
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>XP_005274089
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>XP_005274088
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>XP_006718640
          Length = 1178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H DSLL+ V
Sbjct: 421 HYDSLLVKV 429
>NP_000341
          Length = 2273

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    HTDSLLI 7
            H DSLLI
Sbjct: 2225 HKDSLLI 2231
>NP_001004450
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TDSLLIAV 9
           TD+L+IAV
Sbjct: 112 TDTLVIAV 119
>NP_001171486
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 853 HLDLLMVAV 861
>NP_001171487
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 834 HLDLLMVAV 842
>XP_005246752
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 834 HLDLLMVAV 842
>XP_005246751
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 864 HLDLLMVAV 872
>XP_006712706
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 865 HLDLLMVAV 873
>XP_006712705
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 891 HLDLLMVAV 899
>XP_006712704
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 921 HLDLLMVAV 929
>XP_005246750
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 922 HLDLLMVAV 930
>NP_071341
          Length = 1088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTDSLLIAV 9
           H D L++AV
Sbjct: 823 HLDLLMVAV 831
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.135    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,882
Number of extensions: 492
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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