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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              19     869
NP_001120972                                                           19     869
XP_006716052                                                           19     869
XP_006716051                                                           19     869
NP_115763                                                              16    5631
NP_115597                                                              16    5631
NP_079223                                                              16    5631
XP_006723946                                                           16    5631
XP_005260632                                                           16    5631
XP_005260631                                                           16    5631
XP_005260630                                                           16    5631
XP_006722085                                                           16    5631
XP_006722084                                                           16    5631
XP_005257655                                                           16    5631
XP_006722083                                                           16    5631
XP_005257654                                                           16    5631
XP_005257653                                                           16    5631
XP_005257652                                                           16    5631
XP_006713820                                                           16    5631
XP_005247850                                                           16    5631
XP_005247848                                                           16    5631
XP_006713819                                                           16    5631
XP_005247847                                                           16    5631
XP_006713818                                                           16    5631
XP_006713817                                                           16    5631
XP_006713816                                                           16    5631
XP_005247846                                                           16    5631
NP_001017408                                                           15    9605
NP_065132                                                              15    9605
NP_056173                                                              15    9605
XP_006724049                                                           15    9605
XP_006724048                                                           15    9605

>NP_000236
          Length = 1390

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           HTA IQSEV
Sbjct: 150 HTADIQSEV 158



>NP_001120972
          Length = 1408

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           HTA IQSEV
Sbjct: 150 HTADIQSEV 158



>XP_006716052
          Length = 1409

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           HTA IQSEV
Sbjct: 169 HTADIQSEV 177



>XP_006716051
          Length = 1427

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           HTA IQSEV
Sbjct: 169 HTADIQSEV 177



>NP_115763
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 980 HTAEVESE 987



>NP_115597
          Length = 2715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HTAAIQSE 8
           HT  IQSE
Sbjct: 988 HTITIQSE 995



>NP_079223
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>XP_006723946
          Length = 1414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HTAAIQSE 8
           HT  IQSE
Sbjct: 988 HTITIQSE 995



>XP_005260632
          Length = 2377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HTAAIQSE 8
           HT  IQSE
Sbjct: 988 HTITIQSE 995



>XP_005260631
          Length = 2667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HTAAIQSE 8
           HT  IQSE
Sbjct: 940 HTITIQSE 947



>XP_005260630
          Length = 2693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HTAAIQSE 8
           HT  IQSE
Sbjct: 966 HTITIQSE 973



>XP_006722085
          Length = 907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 644 HTAEVESE 651



>XP_006722084
          Length = 943

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 644 HTAEVESE 651



>XP_005257655
          Length = 971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 672 HTAEVESE 679



>XP_006722083
          Length = 1233

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 934 HTAEVESE 941



>XP_005257654
          Length = 1237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 980 HTAEVESE 987



>XP_005257653
          Length = 1242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 979 HTAEVESE 986



>XP_005257652
          Length = 1279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HTAAIQSE 8
           HTA ++SE
Sbjct: 980 HTAEVESE 987



>XP_006713820
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>XP_005247850
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>XP_005247848
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>XP_006713819
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>XP_005247847
          Length = 983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 79 HTAALQQQ 86



>XP_006713818
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 79 HTAALQQQ 86



>XP_006713817
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 79 HTAALQQQ 86



>XP_006713816
          Length = 999

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 79 HTAALQQQ 86



>XP_005247846
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HTAAIQSE 8
          HTAA+Q +
Sbjct: 91 HTAALQQQ 98



>NP_001017408
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTAAIQSEV 9
           H A +Q+EV
Sbjct: 184 HIAVLQAEV 192



>NP_065132
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HTAAIQSEV 9
           H A +Q+EV
Sbjct: 192 HIAVLQAEV 200



>NP_056173
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           +TAA Q+EV
Sbjct: 636 NTAATQTEV 644



>XP_006724049
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           +TAA Q+EV
Sbjct: 675 NTAATQTEV 683



>XP_006724048
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   HTAAIQSEV 9
           +TAA Q+EV
Sbjct: 565 NTAATQTEV 573



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.110    0.271 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 353,513
Number of extensions: 842
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)