Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_149121                                                              19     869
NP_001164632                                                           19     869
NP_001164630                                                           19     869
NP_001164629                                                           19     869
NP_001164628                                                           19     869
NP_001164627                                                           19     869
XP_005259426                                                           19     869
XP_005259424                                                           19     869
XP_005259423                                                           19     869
NP_079199                                                              17    2528
NP_001005490                                                           17    3301
NP_775966                                                              17    3301
XP_005252872                                                           17    3301
XP_006718230                                                           17    3301
NP_112564                                                              16    5631
NP_001278206                                                           16    5631
NP_000731                                                              16    5631
NP_079265                                                              16    5631
NP_064601                                                              16    5631
XP_005246923                                                           16    5631
XP_005273091                                                           16    5631
XP_005273090                                                           16    5631
XP_006711795                                                           16    5631
XP_005273089                                                           16    5631
XP_005245478                                                           16    5631
XP_005245477                                                           16    5631
XP_005245476                                                           16    5631
XP_005245475                                                           16    5631
NP_002183                                                              16    7355
NP_997186                                                              16    7355
NP_055845                                                              16    7355
NP_001186308                                                           16    7355
NP_001186307                                                           16    7355
NP_001014980                                                           16    7355
NP_004184                                                              16    7355
XP_006718114                                                           16    7355
XP_005270318                                                           16    7355
XP_006718113                                                           16    7355
XP_006718112                                                           16    7355
XP_006718111                                                           16    7355
XP_006718110                                                           16    7355
XP_005248150                                                           16    7355
XP_005248148                                                           16    7355
XP_005248147                                                           16    7355
XP_005248146                                                           16    7355
XP_005248145                                                           16    7355
XP_005248144                                                           16    7355
XP_005248143                                                           16    7355
XP_005248142                                                           16    7355
XP_005248141                                                           16    7355
XP_005248140                                                           16    7355
XP_005248139                                                           16    7355
NP_114171                                                              16    7355
NP_006717                                                              15    9605
NP_064587                                                              15    9605
NP_689783                                                              15    9605
NP_001245211                                                           15    9605
NP_851607                                                              15    9605
NP_001186211                                                           15    9605
NP_065156                                                              15    9605
NP_665810                                                              15    9605
XP_005251429                                                           15    9605
XP_005263434                                                           15    9605
XP_005263433                                                           15    9605
XP_005263432                                                           15    9605
XP_005263431                                                           15    9605
XP_006714492                                                           15    9605
XP_005263430                                                           15    9605
XP_005263429                                                           15    9605
XP_006711530                                                           15    9605
XP_006711529                                                           15    9605
XP_006711528                                                           15    9605
>NP_149121
          Length = 697

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 591 HSTILDYIN 599
>NP_001164632
          Length = 454

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 348 HSTILDYIN 356
>NP_001164630
          Length = 544

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 438 HSTILDYIN 446
>NP_001164629
          Length = 554

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 448 HSTILDYIN 456
>NP_001164628
          Length = 602

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 496 HSTILDYIN 504
>NP_001164627
          Length = 639

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 533 HSTILDYIN 541
>XP_005259426
          Length = 512

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 406 HSTILDYIN 414
>XP_005259424
          Length = 549

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 443 HSTILDYIN 451
>XP_005259423
          Length = 607

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HST+L+++N
Sbjct: 501 HSTILDYIN 509
>NP_079199
          Length = 1887

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    HSTVLNF 7
            HS+VLNF
Sbjct: 1419 HSSVLNF 1425
>NP_001005490
          Length = 312

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSTVLNFV 8
          H+TV NF+
Sbjct: 4  HTTVANFI 11
>NP_775966
          Length = 502

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   HSTVLNFVN 9
           HS++L+F+N
Sbjct: 206 HSSLLDFLN 214
>XP_005252872
          Length = 130

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TVLNFVN 9
          TV+NF+N
Sbjct: 14 TVINFIN 20
>XP_006718230
          Length = 202

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TVLNFVN 9
          TV+NF+N
Sbjct: 14 TVINFIN 20
>NP_112564
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HSTVLNFVN 9
          HS V+ F+N
Sbjct: 14 HSNVVAFIN 22
>NP_001278206
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HSTVLNFVN 9
          HS V+ F+N
Sbjct: 14 HSNVVAFIN 22
>NP_000731
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 374 HSTILN 379
>NP_079265
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HSTV+N +
Sbjct: 816 HSTVINLL 823
>NP_064601
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HS V+N+V
Sbjct: 634 HSNVVNYV 641
>XP_005246923
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HSTV+N +
Sbjct: 642 HSTVINLL 649
>XP_005273091
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 374 HSTILN 379
>XP_005273090
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 374 HSTILN 379
>XP_006711795
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 374 HSTILN 379
>XP_005273089
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 374 HSTILN 379
>XP_005245478
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HS V+N+V
Sbjct: 344 HSNVVNYV 351
>XP_005245477
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HS V+N+V
Sbjct: 344 HSNVVNYV 351
>XP_005245476
          Length = 446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HS V+N+V
Sbjct: 430 HSNVVNYV 437
>XP_005245475
          Length = 519

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSTVLNFV 8
           HS V+N+V
Sbjct: 503 HSNVVNYV 510
>NP_002183
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HSTV+N
Sbjct: 369 HSTVIN 374
>NP_997186
          Length = 1379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    HSTVLNFV 8
            H T +NF+
Sbjct: 1127 HHTAINFI 1134
>NP_055845
          Length = 3013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1733 HTTILNEVD 1741
>NP_001186308
          Length = 1855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1074 STVLSFVS 1081
>NP_001186307
          Length = 1856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1075 STVLSFVS 1082
>NP_001014980
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  HSTVLNFV 8
          H T LNFV
Sbjct: 72 HMTWLNFV 79
>NP_004184
          Length = 1859

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1074 STVLSFVS 1081
>XP_006718114
          Length = 1850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>XP_005270318
          Length = 1860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1075 STVLSFVS 1082
>XP_006718113
          Length = 1881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1096 STVLSFVS 1103
>XP_006718112
          Length = 1889

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>XP_006718111
          Length = 1892

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1107 STVLSFVS 1114
>XP_006718110
          Length = 1893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    STVLNFVN 9
            STVL+FV+
Sbjct: 1108 STVLSFVS 1115
>XP_005248150
          Length = 2044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   HSTVLNFVN 9
           H+T+LN V+
Sbjct: 764 HTTILNEVD 772
>XP_005248148
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1748 HTTILNEVD 1756
>XP_005248147
          Length = 3028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1748 HTTILNEVD 1756
>XP_005248146
          Length = 3073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1840 HTTILNEVD 1848
>XP_005248145
          Length = 3079

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1799 HTTILNEVD 1807
>XP_005248144
          Length = 3099

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1825 HTTILNEVD 1833
>XP_005248143
          Length = 3105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1825 HTTILNEVD 1833
>XP_005248142
          Length = 3114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1840 HTTILNEVD 1848
>XP_005248141
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1839 HTTILNEVD 1847
>XP_005248140
          Length = 3119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1839 HTTILNEVD 1847
>XP_005248139
          Length = 3120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSTVLNFVN 9
            H+T+LN V+
Sbjct: 1840 HTTILNEVD 1848
>NP_114171
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSTVLNF 7
           H T+LNF
Sbjct: 778 HRTMLNF 784
>NP_006717
          Length = 2863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>NP_064587
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HSTV+N
Sbjct: 221 HSTVVN 226
>NP_689783
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSTVLNF 7
           HST L+F
Sbjct: 397 HSTALSF 403
>NP_001245211
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSTVLNF 7
           HST L+F
Sbjct: 397 HSTALSF 403
>NP_851607
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 222 HSTLLN 227
>NP_001186211
          Length = 2851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>NP_065156
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 222 HSTLLN 227
>NP_665810
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSTVLNFVN 9
           H T+L FV+
Sbjct: 126 HRTILAFVS 134
>XP_005251429
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSTVLNF 7
           HST L+F
Sbjct: 397 HSTALSF 403
>XP_005263434
          Length = 1557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263433
          Length = 2832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263432
          Length = 2852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263431
          Length = 2857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_006714492
          Length = 2867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263430
          Length = 2868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_005263429
          Length = 2868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TVLNFVN 9
            TV++FVN
Sbjct: 1340 TVMDFVN 1346
>XP_006711530
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 222 HSTLLN 227
>XP_006711529
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HSTVLN 6
          HST+LN
Sbjct: 80 HSTLLN 85
>XP_006711528
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HSTVLN 6
           HST+LN
Sbjct: 222 HSTLLN 227
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.130    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,537
Number of extensions: 934
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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