Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001129941                                                           18    1935
NP_076432                                                              18    1935
XP_005247785                                                           18    1935
XP_005247784                                                           18    1935
XP_005247783                                                           18    1935
XP_005247782                                                           18    1935
XP_006717092                                                           17    3301
XP_006717091                                                           17    3301
XP_006717090                                                           17    3301
NP_065128                                                              16    5631
NP_001135943                                                           16    5631
XP_005263206                                                           16    5631
XP_005263205                                                           16    5631
NP_009054                                                              16    7355
NP_996816                                                              16    7355
NP_001277114                                                           16    7355
NP_068375                                                              16    7355
NP_003728                                                              16    7355
NP_038478                                                              16    7355
NP_849188                                                              16    7355
NP_001276904                                                           16    7355
XP_005253264                                                           16    7355
XP_006712537                                                           16    7355
XP_005246557                                                           16    7355
XP_006712535                                                           16    7355
XP_006712532                                                           16    7355
XP_006712531                                                           16    7355
XP_006712530                                                           16    7355
XP_006712529                                                           16    7355
XP_006712528                                                           16    7355
XP_006712527                                                           16    7355
XP_005246549                                                           16    7355
XP_006712526                                                           16    7355
XP_006712525                                                           16    7355
XP_005246546                                                           16    7355
XP_006712524                                                           16    7355
XP_005246545                                                           16    7355
NP_000490                                                              15    9605
NP_663160                                                              15    9605
NP_663162                                                              15    9605
NP_056365                                                              15    9605
NP_663161                                                              15    9605
NP_689842                                                              15    9605
NP_597722                                                              15    9605
NP_001273967                                                           15    9605
NP_001273965                                                           15    9605
NP_004237                                                              15    9605
NP_001035878                                                           15    9605
XP_006723847                                                           15    9605
XP_005254242                                                           15    9605
XP_006717041                                                           15    9605
XP_006716794                                                           15    9605
XP_005251446                                                           15    9605
XP_005251445                                                           15    9605
XP_005251444                                                           15    9605
XP_005251443                                                           15    9605
XP_006715746                                                           15    9605
XP_006715745                                                           15    9605
XP_006715744                                                           15    9605
XP_005249755                                                           15    9605
NP_003774                                                              15    9605
NP_004966                                                              15    9605
>NP_001129941
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 55 HSSTRHTSV 63
>NP_076432
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 55 HSSTRHTSV 63
>XP_005247785
          Length = 488

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 55 HSSTRHTSV 63
>XP_005247784
          Length = 569

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 49 HSSTRHTSV 57
>XP_005247783
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 55 HSSTRHTSV 63
>XP_005247782
          Length = 575

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  HSSTRNLSV 9
          HSSTR+ SV
Sbjct: 55 HSSTRHTSV 63
>XP_006717092
          Length = 672

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  HSSTRNL 7
          HSS+RNL
Sbjct: 22 HSSSRNL 28
>XP_006717091
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  HSSTRNL 7
          HSS+RNL
Sbjct: 22 HSSSRNL 28
>XP_006717090
          Length = 737

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  HSSTRNL 7
          HSS+RNL
Sbjct: 22 HSSSRNL 28
>NP_065128
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SSTRNLSV 9
          SST+N+S+
Sbjct: 60 SSTKNISI 67
>NP_001135943
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SSTRNLSV 9
          SST+N+S+
Sbjct: 60 SSTKNISI 67
>XP_005263206
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SSTRNLSV 9
          SST+N+S+
Sbjct: 60 SSTKNISI 67
>XP_005263205
          Length = 462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  SSTRNLSV 9
          SST+N+S+
Sbjct: 60 SSTKNISI 67
>NP_009054
          Length = 1546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSSTRNLSV 9
            H STR+++V
Sbjct: 1131 HGSTRSVAV 1139
>NP_996816
          Length = 5202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    HSSTRNLSV 9
            H STR+++V
Sbjct: 1131 HGSTRSVAV 1139
>NP_001277114
          Length = 931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           H+ST  LSV
Sbjct: 752 HNSTATLSV 760
>NP_068375
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           H+ST  LSV
Sbjct: 762 HNSTATLSV 770
>NP_003728
          Length = 3298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HSSTRNLSV 9
            HSST  LSV
Sbjct: 1595 HSSTGALSV 1603
>NP_038478
          Length = 2168

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>NP_849188
          Length = 2400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           H +TRNL+
Sbjct: 172 HRNTRNLA 179
>NP_001276904
          Length = 2132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 687 HSTPRNLHI 695
>XP_005253264
          Length = 3443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HSSTRNLSV 9
            HSST  LSV
Sbjct: 1740 HSSTGALSV 1748
>XP_006712537
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_005246557
          Length = 2095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 570 HSTPRNLHI 578
>XP_006712535
          Length = 2095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 570 HSTPRNLHI 578
>XP_006712532
          Length = 2141

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 687 HSTPRNLHI 695
>XP_006712531
          Length = 2169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_006712530
          Length = 2176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 687 HSTPRNLHI 695
>XP_006712529
          Length = 2179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_006712528
          Length = 2180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_006712527
          Length = 2203

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_005246549
          Length = 2212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 687 HSTPRNLHI 695
>XP_006712526
          Length = 2212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 687 HSTPRNLHI 695
>XP_006712525
          Length = 2212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_005246546
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_006712524
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>XP_005246545
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HS+ RNL +
Sbjct: 689 HSTPRNLHI 697
>NP_000490
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   HSSTRNLSV 9
           HS+TR+ S+
Sbjct: 388 HSTTRDTSL 396
>NP_663160
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 271 HSSNPNLS 278
>NP_663162
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 271 HSSNPNLS 278
>NP_056365
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 302 HSSNPNLS 309
>NP_663161
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 302 HSSNPNLS 309
>NP_689842
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           HSSTR+ S
Sbjct: 133 HSSTRSHS 140
>NP_597722
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          H+S+ NLS
Sbjct: 6  HTSSENLS 13
>NP_001273967
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          H+S+ NLS
Sbjct: 6  HTSSENLS 13
>NP_001273965
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          H+S+ NLS
Sbjct: 6  HTSSENLS 13
>NP_004237
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           HSS  N+SV
Sbjct: 108 HSSPGNVSV 116
>NP_001035878
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           HSSTR+ S
Sbjct: 288 HSSTRSHS 295
>XP_006723847
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           H STR+ S+
Sbjct: 850 HGSTRDQSI 858
>XP_005254242
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   HSSTRNLSV 9
           HS+TR+ S+
Sbjct: 388 HSTTRDTSL 396
>XP_006717041
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          H+S+ NLS
Sbjct: 6  HTSSENLS 13
>XP_006716794
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           HSSTR+ S
Sbjct: 288 HSSTRSHS 295
>XP_005251446
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           HSSTR+ S
Sbjct: 288 HSSTRSHS 295
>XP_005251445
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          HSSTR+ S
Sbjct: 66 HSSTRSHS 73
>XP_005251444
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  HSSTRNLS 8
          HSSTR+ S
Sbjct: 66 HSSTRSHS 73
>XP_005251443
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HSSTRNLS 8
           HSSTR+ S
Sbjct: 133 HSSTRSHS 140
>XP_006715746
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 271 HSSNPNLS 278
>XP_006715745
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 302 HSSNPNLS 309
>XP_006715744
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 271 HSSNPNLS 278
>XP_005249755
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HSSTRNLS 8
           HSS  NLS
Sbjct: 302 HSSNPNLS 309
>NP_003774
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  HSSTRNL 7
          HSS RN+
Sbjct: 76 HSSLRNI 82
>NP_004966
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSTRNLSV 9
           H STR+ S+
Sbjct: 850 HGSTRDQSI 858
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.108    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 407,634
Number of extensions: 688
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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