Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              21     229
NP_444254                                                              21     229
NP_444253                                                              21     229
NP_444255                                                              21     229
XP_005247551                                                           21     229
XP_005247550                                                           21     229
XP_006713712                                                           21     229
XP_005247549                                                           21     229
NP_689763                                                              17    2528
NP_001188358                                                           17    2528
NP_036427                                                              17    2528
NP_001186210                                                           17    2528
XP_006724247                                                           17    2528
XP_006724246                                                           17    2528
XP_006724245                                                           17    2528
XP_006724244                                                           17    2528
XP_006724243                                                           17    2528
XP_005261477                                                           17    2528
XP_005261476                                                           17    2528
XP_005261474                                                           17    2528
XP_006724242                                                           17    2528
XP_005261473                                                           17    2528
XP_005261472                                                           17    2528
XP_006714820                                                           17    2528
XP_005268437                                                           17    2528
NP_005969                                                              17    3301
NP_443137                                                              17    4312
NP_001129243                                                           17    4312
NP_002942                                                              17    4312
XP_006723915                                                           17    4312
XP_006723914                                                           17    4312
XP_005260548                                                           17    4312
XP_006723913                                                           17    4312
XP_006723912                                                           17    4312
XP_006712292                                                           17    4312
XP_005246323                                                           17    4312
XP_005246322                                                           17    4312
XP_006712291                                                           17    4312
XP_005246320                                                           17    4312
NP_001360                                                              16    5631
XP_005248319                                                           16    5631
NP_001136007                                                           16    5631
NP_064615                                                              16    7355
NP_057217                                                              16    7355
NP_001185619                                                           16    7355
NP_001035754                                                           16    7355
NP_001138482                                                           16    7355
XP_005258567                                                           16    7355
XP_005263747                                                           16    7355
NP_789780                                                              16    7355
NP_060619                                                              15    9605
NP_059142                                                              15    9605
NP_060734                                                              15    9605
NP_057287                                                              15    9605
NP_690621                                                              15    9605
NP_690620                                                              15    9605
NP_690619                                                              15    9605
NP_001035723                                                           15    9605
NP_002812                                                              15    9605
NP_001257327                                                           15    9605
XP_006724089                                                           15    9605
XP_005250062                                                           15    9605
XP_005250061                                                           15    9605
XP_006716084                                                           15    9605
XP_005250060                                                           15    9605
XP_005250059                                                           15    9605
NP_542984                                                              15    9605
>NP_444256
          Length = 1794

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 877 HSPQQVDFR 885
>NP_444254
          Length = 1845

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 877 HSPQQVDFR 885
>NP_444253
          Length = 1914

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 946 HSPQQVDFR 954
>NP_444255
          Length = 1863

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 946 HSPQQVDFR 954
>XP_005247551
          Length = 1855

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 887 HSPQQVDFR 895
>XP_005247550
          Length = 1856

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 956 HSPQQVDFR 964
>XP_006713712
          Length = 1923

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 956 HSPQQVDFR 964
>XP_005247549
          Length = 1924

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HSSQQVDFR 9
           HS QQVDFR
Sbjct: 956 HSPQQVDFR 964
>NP_689763
          Length = 729

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           HS QQ D R
Sbjct: 696 HSGQQTDLR 704
>NP_001188358
          Length = 2170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 916 HSAQQVD 922
>NP_036427
          Length = 2220

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>NP_001186210
          Length = 2220

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724247
          Length = 1189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724246
          Length = 2103

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724245
          Length = 2191

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724244
          Length = 2191

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724243
          Length = 2196

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_005261477
          Length = 2200

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_005261476
          Length = 2210

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 921 HSAQQVD 927
>XP_005261474
          Length = 2225

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006724242
          Length = 2226

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_005261473
          Length = 2250

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_005261472
          Length = 2255

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HS+QQVD
Sbjct: 966 HSAQQVD 972
>XP_006714820
          Length = 729

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           HS QQ D R
Sbjct: 696 HSGQQTDLR 704
>XP_005268437
          Length = 735

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           HS QQ D R
Sbjct: 702 HSGQQTDLR 710
>NP_005969
          Length = 97

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  HSSQQVDFR 9
          +S QQVDF+
Sbjct: 65 NSDQQVDFQ 73
>NP_443137
          Length = 1092

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>NP_001129243
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 138 HLSQQADLR 146
>NP_002942
          Length = 631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 170 HLSQQADLR 178
>XP_006723915
          Length = 615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 186 HLSQQADLR 194
>XP_006723914
          Length = 631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 186 HLSQQADLR 194
>XP_005260548
          Length = 647

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 170 HLSQQADLR 178
>XP_006723913
          Length = 647

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 186 HLSQQADLR 194
>XP_006723912
          Length = 663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H SQQ D R
Sbjct: 186 HLSQQADLR 194
>XP_006712292
          Length = 641

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>XP_005246323
          Length = 1069

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>XP_005246322
          Length = 1084

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>XP_006712291
          Length = 1086

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>XP_005246320
          Length = 1087

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SQQVDFR 9
          SQQ DFR
Sbjct: 9  SQQTDFR 15
>NP_001360
          Length = 4624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSQQVDFR 9
           HSS  ++FR
Sbjct: 986 HSSHTINFR 994
>XP_005248319
          Length = 4609

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSSQQVDFR 9
           HSS  ++FR
Sbjct: 971 HSSHTINFR 979
>NP_001136007
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  HSSQQVDFR 9
          HS  QVDF+
Sbjct: 74 HSRFQVDFQ 82
>NP_064615
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SQQVDFR 9
           SQ++DFR
Sbjct: 189 SQELDFR 195
>NP_057217
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HSSQQVDF 8
           H+S +VDF
Sbjct: 120 HASAKVDF 127
>NP_001185619
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SQQVDFR 9
           SQ++DFR
Sbjct: 189 SQELDFR 195
>NP_001035754
          Length = 794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SQQVDFR 9
           SQ++DFR
Sbjct: 189 SQELDFR 195
>NP_001138482
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HSSQQVD 7
           HSS+++D
Sbjct: 245 HSSEEID 251
>XP_005258567
          Length = 1036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           H SQ+ DF
Sbjct: 643 HESQEEDF 650
>XP_005263747
          Length = 117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HSSQQVDF 8
          H+S +VDF
Sbjct: 12 HASAKVDF 19
>NP_789780
          Length = 1043

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           H SQ+ DF
Sbjct: 643 HESQEEDF 650
>NP_060619
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           HS QQ+ F
Sbjct: 385 HSRQQLSF 392
>NP_059142
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           HS  +VDF
Sbjct: 232 HSKYKVDF 239
>NP_060734
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSSQQVDFR 9
           H S + DFR
Sbjct: 222 HGSIEADFR 230
>NP_057287
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 58 HSSRKVD 64
>NP_690621
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQVDFR 9
           QQ+DFR
Sbjct: 783 QQLDFR 788
>NP_690620
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQVDFR 9
           QQ+DFR
Sbjct: 709 QQLDFR 714
>NP_690619
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQVDFR 9
           QQ+DFR
Sbjct: 799 QQLDFR 804
>NP_001035723
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 14 HSSRKVD 20
>NP_002812
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQVDFR 9
           QQ+DFR
Sbjct: 839 QQLDFR 844
>NP_001257327
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QQVDFR 9
           QQ+DFR
Sbjct: 847 QQLDFR 852
>XP_006724089
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           HS  +VDF
Sbjct: 232 HSKYKVDF 239
>XP_005250062
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 58 HSSRKVD 64
>XP_005250061
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 14 HSSRKVD 20
>XP_006716084
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 54 HSSRKVD 60
>XP_005250060
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 58 HSSRKVD 64
>XP_005250059
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HSSQQVD 7
          HSS++VD
Sbjct: 58 HSSRKVD 64
>NP_542984
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HSSQQVDF 8
           HS  +VDF
Sbjct: 232 HSKYKVDF 239
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.124    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 491,546
Number of extensions: 874
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package