Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_000615                                                              16    7355
NP_001121                                                              16    7355
NP_945321                                                              16    7355
NP_945320                                                              16    7355
XP_006722727                                                           16    7355
NP_060420                                                              15    9605
NP_573400                                                              15    9605
NP_008981                                                              15    9605
NP_001264044                                                           15    9605
NP_055458                                                              15    9605
NP_001230271                                                           15    9605
NP_001269513                                                           15    9605
NP_001129120                                                           15    9605
NP_056013                                                              15    9605
NP_001098714                                                           15    9605
NP_001274365                                                           15    9605
NP_573439                                                              15    9605
NP_573438                                                              15    9605
NP_001181930                                                           15    9605
NP_005695                                                              15    9605
NP_076999                                                              15    9605
NP_002835                                                              15    9605
NP_002790                                                              15    9605
NP_060686                                                              15    9605
NP_003438                                                              15    9605
XP_006725090                                                           15    9605
XP_006725086                                                           15    9605
XP_006725085                                                           15    9605
XP_006725084                                                           15    9605
XP_006725083                                                           15    9605
XP_006725082                                                           15    9605
XP_006723752                                                           15    9605
XP_006723751                                                           15    9605
XP_006723750                                                           15    9605
XP_006723749                                                           15    9605
XP_006723748                                                           15    9605
XP_006722401                                                           15    9605
XP_006722400                                                           15    9605
XP_006722399                                                           15    9605
XP_006722398                                                           15    9605
XP_005257549                                                           15    9605
XP_005257548                                                           15    9605
XP_005251122                                                           15    9605
XP_005271814                                                           15    9605
XP_005271813                                                           15    9605
XP_006715738                                                           15    9605
XP_005271812                                                           15    9605
XP_005271810                                                           15    9605
XP_005271809                                                           15    9605
XP_005271808                                                           15    9605
XP_005271807                                                           15    9605
XP_006715601                                                           15    9605
XP_005267142                                                           15    9605
XP_006715600                                                           15    9605
XP_005267139                                                           15    9605
XP_006715599                                                           15    9605
XP_006715598                                                           15    9605
XP_006715242                                                           15    9605
XP_005249428                                                           15    9605
XP_005249429                                                           15    9605
XP_005249430                                                           15    9605
XP_006710765                                                           15    9605
XP_006710336                                                           15    9605
XP_006710335                                                           15    9605
XP_006710334                                                           15    9605
XP_006710333                                                           15    9605
XP_006710332                                                           15    9605
NP_002836                                                              15    9605
>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HSAVLEADK 9
            HSAVLEA K
Sbjct: 1053 HSAVLEAGK 1061
>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HSAVLEADK 9
            HSAVLEA K
Sbjct: 1072 HSAVLEAGK 1080
>NP_000615
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HSAVLEADK 9
           H AV+E D+
Sbjct: 349 HKAVVEVDE 357
>NP_001121
          Length = 197

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HSAVLEADK 9
          HS  LE DK
Sbjct: 41 HSLKLECDK 49
>NP_945321
          Length = 196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HSAVLEADK 9
          HS  LE DK
Sbjct: 41 HSLKLECDK 49
>NP_945320
          Length = 264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           HS  LE DK
Sbjct: 108 HSLKLECDK 116
>XP_006722727
          Length = 263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           HS  LE DK
Sbjct: 108 HSLKLECDK 116
>NP_060420
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H AVLEA
Sbjct: 513 HRAVLEA 519
>NP_573400
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1156 HDAILEA 1162
>NP_008981
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1137 HDAILEA 1143
>NP_001264044
          Length = 4516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HSAVLEADK 9
            H A+ +ADK
Sbjct: 3741 HRAIEQADK 3749
>NP_055458
          Length = 1163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    HSAVLEAD 8
            HS V E+D
Sbjct: 1120 HSVVFESD 1127
>NP_001230271
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H AVLEA
Sbjct: 513 HRAVLEA 519
>NP_001269513
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  HSAVLEAD 8
          HSAV E D
Sbjct: 23 HSAVEETD 30
>NP_001129120
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1142 HDAILEA 1148
>NP_056013
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1110 HSALMEA 1116
>NP_001098714
          Length = 1465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1161 HDAILEA 1167
>NP_001274365
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1167 HSALMEA 1173
>NP_573439
          Length = 1436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1128 HDAILEA 1134
>NP_573438
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1134 HDAILEA 1140
>NP_001181930
          Length = 1433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1125 HDAILEA 1131
>NP_005695
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1138 HDAILEA 1144
>NP_076999
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  HSAVLEADK 9
          HS V+  DK
Sbjct: 60 HSLVIRGDK 68
>NP_002835
          Length = 1440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1136 HDAILEA 1142
>NP_002790
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SAVLEAD 8
          +AVLEAD
Sbjct: 22 NAVLEAD 28
>NP_060686
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SAVLEAD 8
           SAVLE+D
Sbjct: 575 SAVLESD 581
>NP_003438
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           H+AV   DK
Sbjct: 334 HAAVFSGDK 342
>XP_006725090
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H A+LEA
Sbjct: 407 HDAILEA 413
>XP_006725086
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H A+LEA
Sbjct: 753 HDAILEA 759
>XP_006725085
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1071 HDAILEA 1077
>XP_006725084
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1071 HDAILEA 1077
>XP_006725083
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1135 HDAILEA 1141
>XP_006725082
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1141 HDAILEA 1147
>XP_006723752
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1083 HDAILEA 1089
>XP_006723751
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1123 HDAILEA 1129
>XP_006723750
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1123 HDAILEA 1129
>XP_006723749
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1124 HDAILEA 1130
>XP_006723748
          Length = 1437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1133 HDAILEA 1139
>XP_006722401
          Length = 1432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1128 HDAILEA 1134
>XP_006722400
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1165 HDAILEA 1171
>XP_006722399
          Length = 1477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1173 HDAILEA 1179
>XP_006722398
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1190 HDAILEA 1196
>XP_005257549
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H AVLEA
Sbjct: 513 HRAVLEA 519
>XP_005257548
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H AVLEA
Sbjct: 120 HRAVLEA 126
>XP_005251122
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  HSAVLEADK 9
          HS V+  DK
Sbjct: 60 HSLVIRGDK 68
>XP_005271814
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HSAVLEA 7
           HSA++EA
Sbjct: 896 HSALMEA 902
>XP_005271813
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1110 HSALMEA 1116
>XP_006715738
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1125 HSALMEA 1131
>XP_005271812
          Length = 1245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1182 HSALMEA 1188
>XP_005271810
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1125 HSALMEA 1131
>XP_005271809
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1182 HSALMEA 1188
>XP_005271808
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1167 HSALMEA 1173
>XP_005271807
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HSAVLEA 7
            HSA++EA
Sbjct: 1182 HSALMEA 1188
>XP_006715601
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H A+LEA
Sbjct: 777 HDAILEA 783
>XP_005267142
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1135 HDAILEA 1141
>XP_006715600
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1141 HDAILEA 1147
>XP_005267139
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1160 HDAILEA 1166
>XP_006715599
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1165 HDAILEA 1171
>XP_006715598
          Length = 1470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1166 HDAILEA 1172
>XP_006715242
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           H+AV   DK
Sbjct: 160 HAAVFSGDK 168
>XP_005249428
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           H+AV   DK
Sbjct: 334 HAAVFSGDK 342
>XP_005249429
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           H+AV   DK
Sbjct: 334 HAAVFSGDK 342
>XP_005249430
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HSAVLEADK 9
           H+AV   DK
Sbjct: 334 HAAVFSGDK 342
>XP_006710765
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  HSAVLEAD 8
          HSAV E D
Sbjct: 23 HSAVEETD 30
>XP_006710336
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H A+LEA
Sbjct: 869 HDAILEA 875
>XP_006710335
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1062 HDAILEA 1068
>XP_006710334
          Length = 1292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HSAVLEA 7
           H A+LEA
Sbjct: 984 HDAILEA 990
>XP_006710333
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1131 HDAILEA 1137
>XP_006710332
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1134 HDAILEA 1140
>NP_002836
          Length = 1452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HSAVLEA 7
            H A+LEA
Sbjct: 1148 HDAILEA 1154
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.116    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,010
Number of extensions: 1020
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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