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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000194                                                              19     869
XP_006713944                                                           19     869
NP_001107644                                                           18    1135
NP_003620                                                              18    1135
XP_005271347                                                           18    1135
NP_001094861                                                           16    5631
NP_872393                                                              16    7355
XP_006726904                                                           16    7355
XP_006726903                                                           16    7355
XP_006726902                                                           16    7355
XP_005262021                                                           16    7355
XP_005262020                                                           16    7355
XP_006712515                                                           16    7355
XP_006712513                                                           16    7355
XP_006712512                                                           16    7355
XP_006712511                                                           16    7355
XP_006712510                                                           16    7355
XP_006712509                                                           16    7355
XP_005246533                                                           16    7355
XP_006712508                                                           16    7355
XP_006710186                                                           16    7355
XP_006710185                                                           16    7355
NP_115893                                                              16    7355
NP_060228                                                              16    7355
NP_689879                                                              15    9605
NP_115696                                                              15    9605
NP_055847                                                              15    9605
NP_060267                                                              15    9605
NP_060662                                                              15    9605
XP_005259650                                                           15    9605
XP_005266355                                                           15    9605
XP_005266354                                                           15    9605
XP_005266353                                                           15    9605
XP_005266352                                                           15    9605
XP_005253221                                                           15    9605
XP_006711815                                                           15    9605

>NP_000194
          Length = 653

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  HRGVRQIR 8
          HRG++Q+R
Sbjct: 82 HRGIKQVR 89



>XP_006713944
          Length = 722

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  HRGVRQIR 8
          HRG++Q+R
Sbjct: 82 HRGIKQVR 89



>NP_001107644
          Length = 461

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+GVRQ RL
Sbjct: 318 HKGVRQKRL 326



>NP_003620
          Length = 461

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+GVRQ RL
Sbjct: 318 HKGVRQKRL 326



>XP_005271347
          Length = 478

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+GVRQ RL
Sbjct: 335 HKGVRQKRL 343



>NP_001094861
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GVRQIRL 9
           G+RQIRL
Sbjct: 316 GLRQIRL 322



>NP_872393
          Length = 3234

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3038 RGLRQLR 3044



>XP_006726904
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RGVRQIRL 9
          RG+RQ++L
Sbjct: 91 RGLRQLQL 98




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 288 RGLRQLQL 295




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 367 RGLRQLQL 374



>XP_006726903
          Length = 459

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RGVRQIRL 9
          RG+RQ++L
Sbjct: 91 RGLRQLQL 98




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 288 RGLRQLQL 295




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 357 RGLRQLQL 364



>XP_006726902
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RGVRQIRL 9
          RG+RQ++L
Sbjct: 91 RGLRQLQL 98




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 288 RGLRQLQL 295




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 367 RGLRQLQL 374



>XP_005262021
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 167 RGLRQLQL 174




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 295 RGLRQLQL 302




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 364 RGLRQLQL 371




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 512 RGLRQLQL 519



>XP_005262020
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 167 RGLRQLQL 174




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 295 RGLRQLQL 302




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 364 RGLRQLQL 371




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 502 RGLRQLQL 509



>XP_006712515
          Length = 3232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3036 RGLRQLR 3042



>XP_006712513
          Length = 3220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3024 RGLRQLR 3030



>XP_006712512
          Length = 3237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3041 RGLRQLR 3047



>XP_006712511
          Length = 3256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3060 RGLRQLR 3066



>XP_006712510
          Length = 3305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3109 RGLRQLR 3115



>XP_006712509
          Length = 3319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3123 RGLRQLR 3129



>XP_005246533
          Length = 3323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3127 RGLRQLR 3133



>XP_006712508
          Length = 3324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3128 RGLRQLR 3134



>XP_006710186
          Length = 463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RGVRQIRL 9
          RG+RQ++L
Sbjct: 91 RGLRQLQL 98




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 219 RGLRQLQL 226




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 357 RGLRQLQL 364



>XP_006710185
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RGVRQIRL 9
          RG+RQ++L
Sbjct: 91 RGLRQLQL 98




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 219 RGLRQLQL 226




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 357 RGLRQLQL 364




 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+RQ++L
Sbjct: 436 RGLRQLQL 443



>NP_115893
          Length = 3258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    RGVRQIR 8
            RG+RQ+R
Sbjct: 3062 RGLRQLR 3068



>NP_060228
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GVRQIRL 9
          G+RQ+RL
Sbjct: 88 GIRQMRL 94



>NP_689879
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  HRGVRQIRL 9
          H G  Q+RL
Sbjct: 14 HEGFEQMRL 22



>NP_115696
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+++IRL
Sbjct: 362 RGLKKIRL 369



>NP_055847
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+G+ ++RL
Sbjct: 927 HKGLSRLRL 935



>NP_060267
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   GVRQIRL 9
           G+R++RL
Sbjct: 276 GIREVRL 282



>NP_060662
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HRGVRQIR 8
          HR +R+IR
Sbjct: 74 HRRLREIR 81



>XP_005259650
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   GVRQIRL 9
           G+R++RL
Sbjct: 128 GIREVRL 134



>XP_005266355
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+G+ ++RL
Sbjct: 927 HKGLSRLRL 935



>XP_005266354
          Length = 1411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+G+ ++RL
Sbjct: 927 HKGLSRLRL 935



>XP_005266353
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+G+ ++RL
Sbjct: 927 HKGLSRLRL 935



>XP_005266352
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HRGVRQIRL 9
           H+G+ ++RL
Sbjct: 927 HKGLSRLRL 935



>XP_005253221
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RGVRQIRL 9
           RG+++IRL
Sbjct: 370 RGLKKIRL 377



>XP_006711815
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  HRGVRQIRL 9
          H G  Q+RL
Sbjct: 14 HEGFEQMRL 22



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.154    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 510,877
Number of extensions: 764
Number of successful extensions: 53
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)