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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     390
NP_000242                                                              20     390
XP_005264389                                                           20     390
NP_060474                                                              18    1935
XP_005247626                                                           18    1935
XP_005247625                                                           18    1935
NP_001004458                                                           17    3301
NP_001004459                                                           17    3301
NP_001073867                                                           16    5631
NP_877435                                                              16    5631
XP_005251911                                                           16    5631
XP_005251910                                                           16    5631
XP_005251909                                                           16    5631
XP_005251908                                                           16    5631
XP_005251907                                                           16    5631
NP_671709                                                              16    5631
NP_000548                                                              16    7355
NP_001157932                                                           16    7355
NP_001004731                                                           16    7355
NP_003631                                                              15    9605
NP_002102                                                              15    9605
NP_116207                                                              15    9605
NP_001138356                                                           15    9605
NP_598003                                                              15    9605
XP_005252342                                                           15    9605
XP_005270560                                                           15    9605
NP_001001955                                                           15    9605
NP_001004703                                                           15    9605

>NP_001245210
          Length = 868

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQKLLL VF
Sbjct: 362 HQKLLLAVF 370



>NP_000242
          Length = 934

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQKLLL VF
Sbjct: 428 HQKLLLAVF 436



>XP_005264389
          Length = 921

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQKLLL VF
Sbjct: 428 HQKLLLAVF 436



>NP_060474
          Length = 275

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQ L+LVVF
Sbjct: 153 HQLLVLVVF 161



>XP_005247626
          Length = 291

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQ L+LVVF
Sbjct: 169 HQLLVLVVF 177



>XP_005247625
          Length = 291

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   HQKLLLVVF 9
           HQ L+LVVF
Sbjct: 169 HQLLVLVVF 177



>NP_001004458
          Length = 325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  HQKLLLVVF 9
          HQ LL V+F
Sbjct: 36 HQNLLFVLF 44



>NP_001004459
          Length = 325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  HQKLLLVVF 9
          HQ LL V+F
Sbjct: 36 HQNLLFVLF 44



>NP_001073867
          Length = 2017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    HQKLLL 6
            HQKLLL
Sbjct: 1049 HQKLLL 1054



>NP_877435
          Length = 1102

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QKLLLVVF 9
           ++LLLVVF
Sbjct: 225 ERLLLVVF 232



>XP_005251911
          Length = 1839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HQKLLL 6
           HQKLLL
Sbjct: 871 HQKLLL 876



>XP_005251910
          Length = 1839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HQKLLL 6
           HQKLLL
Sbjct: 871 HQKLLL 876



>XP_005251909
          Length = 1839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HQKLLL 6
           HQKLLL
Sbjct: 871 HQKLLL 876



>XP_005251908
          Length = 1839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HQKLLL 6
           HQKLLL
Sbjct: 871 HQKLLL 876



>XP_005251907
          Length = 1845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   HQKLLL 6
           HQKLLL
Sbjct: 877 HQKLLL 882



>NP_671709
          Length = 173

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HQKLLLVV 8
           H+KL+L+V
Sbjct: 166 HKKLVLIV 173



>NP_000548
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HQKLLLVVF 9
           H+K L +VF
Sbjct: 337 HEKALFLVF 345



>NP_001157932
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KLLLVVF 9
           KLLL++F
Sbjct: 334 KLLLIIF 340



>NP_001004731
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QKLLLVVF 9
          Q+LL VVF
Sbjct: 75 QRLLFVVF 82



>NP_003631
          Length = 1332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    HQKLLLVV 8
            H+K LLVV
Sbjct: 1134 HKKRLLVV 1141



>NP_002102
          Length = 3144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    HQKLLLVV 8
            H+KLLL +
Sbjct: 2596 HEKLLLQI 2603



>NP_116207
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HQKLLLV 7
           H+KLLL+
Sbjct: 306 HEKLLLM 312



>NP_001138356
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HQKLLLV 7
           H++LLLV
Sbjct: 138 HERLLLV 144



>NP_598003
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HQKLLLV 7
           H++LLLV
Sbjct: 138 HERLLLV 144



>XP_005252342
          Length = 1218

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    HQKLLLVV 8
            H+K LLVV
Sbjct: 1020 HKKRLLVV 1027



>XP_005270560
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HQKLLLV 7
           H++LLLV
Sbjct: 138 HERLLLV 144



>NP_001001955
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKLLLVVF 9
          QK++ VVF
Sbjct: 22 QKIIFVVF 29



>NP_001004703
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKLLLVVF 9
          QK++ VVF
Sbjct: 22 QKIIFVVF 29



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.347    0.156    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,253
Number of extensions: 751
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)