Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_058640                                                              17    3301
NP_001243197                                                           17    3301
NP_001243196                                                           17    3301
NP_115967                                                              17    3301
NP_003836                                                              17    3301
XP_006718107                                                           17    3301
XP_006718106                                                           17    3301
NP_689475                                                              17    4312
NP_443188                                                              17    4312
XP_006722996                                                           17    4312
XP_005260201                                                           17    4312
XP_005260199                                                           17    4312
XP_006721080                                                           17    4312
XP_006721079                                                           17    4312
XP_005255141                                                           17    4312
NP_078832                                                              16    5631
NP_006725                                                              16    5631
XP_005271723                                                           16    5631
XP_005271722                                                           16    5631
XP_005269873                                                           16    5631
XP_005267014                                                           16    5631
NP_852004                                                              16    7355
NP_001193795                                                           16    7355
NP_000556                                                              16    7355
NP_940905                                                              16    7355
NP_001274748                                                           16    7355
NP_001274749                                                           16    7355
NP_001103132                                                           16    7355
NP_612364                                                              16    7355
NP_001269618                                                           16    7355
NP_001138495                                                           16    7355
NP_076982                                                              16    7355
NP_001740                                                              16    7355
NP_001269619                                                           16    7355
NP_001269617                                                           16    7355
XP_005259354                                                           16    7355
XP_005259353                                                           16    7355
XP_005259352                                                           16    7355
XP_005257833                                                           16    7355
XP_006722227                                                           16    7355
XP_005252259                                                           16    7355
XP_006717345                                                           16    7355
XP_005252255                                                           16    7355
XP_005252253                                                           16    7355
XP_005252252                                                           16    7355
XP_005252250                                                           16    7355
XP_005245197                                                           16    7355
XP_005245196                                                           16    7355
XP_006711362                                                           16    7355
XP_006711361                                                           16    7355
XP_006711360                                                           16    7355
XP_006711359                                                           16    7355
XP_006711358                                                           16    7355
XP_006711357                                                           16    7355
NP_037505                                                              16    7355
NP_001003962                                                           16    7355
NP_001004737                                                           16    7355
NP_001004736                                                           16    7355
NP_001005516                                                           16    7355
NP_066270                                                              15    9605
NP_055523                                                              15    9605
NP_001015001                                                           15    9605
NP_001816                                                              15    9605
NP_689689                                                              15    9605
NP_055318                                                              15    9605
XP_006719769                                                           15    9605
XP_006719406                                                           15    9605
XP_005248477                                                           15    9605
XP_006712789                                                           15    9605
XP_005270533                                                           15    9605
NP_001021100                                                           15    9605
NP_997204                                                              15    9605
NP_001093206                                                           15    9605
NP_001093205                                                           15    9605
>NP_058640
          Length = 299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP LKT A
Sbjct: 284 HPKLKTTA 291
>NP_001243197
          Length = 1026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HPSLKTKA 8
           HPS++TK+
Sbjct: 473 HPSVQTKS 480
>NP_001243196
          Length = 1320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HPSLKTKA 8
           HPS++TK+
Sbjct: 767 HPSVQTKS 774
>NP_115967
          Length = 1320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HPSLKTKA 8
           HPS++TK+
Sbjct: 767 HPSVQTKS 774
>NP_003836
          Length = 520

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  HPSLKTK 7
          HPS+KT+
Sbjct: 14 HPSIKTQ 20
>XP_006718107
          Length = 1330

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HPSLKTKA 8
           HPS++TK+
Sbjct: 777 HPSVQTKS 784
>XP_006718106
          Length = 1338

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HPSLKTKA 8
           HPS++TK+
Sbjct: 785 HPSVQTKS 792
>NP_689475
          Length = 499

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HPSLKTK 7
           HPSL+T+
Sbjct: 170 HPSLRTQ 176
>NP_443188
          Length = 577

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSLKTK +
Sbjct: 180 PSLKTKLL 187
>XP_006722996
          Length = 404

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HPSLKTK 7
           HPSL+T+
Sbjct: 175 HPSLRTQ 181
>XP_005260201
          Length = 420

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HPSLKTK 7
           HPSL+T+
Sbjct: 175 HPSLRTQ 181
>XP_005260199
          Length = 504

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HPSLKTK 7
           HPSL+T+
Sbjct: 175 HPSLRTQ 181
>XP_006721080
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSLKTK +
Sbjct: 180 PSLKTKLL 187
>XP_006721079
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSLKTK +
Sbjct: 180 PSLKTKLL 187
>XP_005255141
          Length = 577

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSLKTK +
Sbjct: 180 PSLKTKLL 187
>NP_078832
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  PSLKTK 7
          PSLKTK
Sbjct: 33 PSLKTK 38
>NP_006725
          Length = 2446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           +PSL TKA
Sbjct: 352 NPSLNTKA 359
>XP_005271723
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  PSLKTK 7
          PSLKTK
Sbjct: 33 PSLKTK 38
>XP_005271722
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  PSLKTK 7
          PSLKTK
Sbjct: 33 PSLKTK 38
>XP_005269873
          Length = 129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP L+T A
Sbjct: 117 HPGLRTNA 124
>XP_005267014
          Length = 2446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           +PSL TKA
Sbjct: 352 NPSLNTKA 359
>NP_852004
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>NP_001193795
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>NP_000556
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>NP_940905
          Length = 1135

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HPSLKTKAM 9
            HP L+ K+M
Sbjct: 1007 HPLLRRKSM 1015
>NP_001274748
          Length = 1111

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP L+ K+M
Sbjct: 983 HPLLRRKSM 991
>NP_001274749
          Length = 1068

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP L+ K+M
Sbjct: 940 HPLLRRKSM 948
>NP_001103132
          Length = 4284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    HPSLKTKAM 9
            HP  KTK +
Sbjct: 1328 HPLAKTKTL 1336
>NP_612364
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP L+T A
Sbjct: 205 HPELRTHA 212
>NP_001269618
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 286 HPTQKSKA 293
>NP_001138495
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP L+T A
Sbjct: 205 HPELRTHA 212
>NP_076982
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 359 HPTQKSKA 366
>NP_001740
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 131 HPDLKT 136
>NP_001269619
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 291 HPTQKSKA 298
>NP_001269617
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 358 HPTQKSKA 365
>XP_005259354
          Length = 156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  HPSLKT 6
          HP LKT
Sbjct: 19 HPDLKT 24
>XP_005259353
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 131 HPDLKT 136
>XP_005259352
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 131 HPDLKT 136
>XP_005257833
          Length = 425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP L+T A
Sbjct: 205 HPELRTHA 212
>XP_006722227
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HPSLKTKA 8
           HP L+T A
Sbjct: 213 HPELRTHA 220
>XP_005252259
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HPSLKTKA 8
          HP+ K+KA
Sbjct: 60 HPTQKSKA 67
>XP_006717345
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 286 HPTQKSKA 293
>XP_005252255
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 291 HPTQKSKA 298
>XP_005252253
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 320 HPTQKSKA 327
>XP_005252252
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 321 HPTQKSKA 328
>XP_005252250
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HPSLKTKA 8
           HP+ K+KA
Sbjct: 359 HPTQKSKA 366
>XP_005245197
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>XP_005245196
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>XP_006711362
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>XP_006711361
          Length = 484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           PSL TKA+
Sbjct: 140 PSLTTKAV 147
>XP_006711360
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP L+ K+M
Sbjct: 571 HPLLRRKSM 579
>XP_006711359
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP L+ K+M
Sbjct: 624 HPLLRRKSM 632
>XP_006711358
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP L+ K+M
Sbjct: 990 HPLLRRKSM 998
>XP_006711357
          Length = 1142

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HPSLKTKAM 9
            HP L+ K+M
Sbjct: 1014 HPLLRRKSM 1022
>NP_037505
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 711 HPQLKT 716
>NP_001003962
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 131 HPDLKT 136
>NP_001004737
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  HPSLKT 6
          HP LKT
Sbjct: 20 HPELKT 25
>NP_001004736
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  HPSLKT 6
          HP LKT
Sbjct: 20 HPELKT 25
>NP_001005516
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1  HPSLKT 6
          HP LKT
Sbjct: 20 HPKLKT 25
>NP_066270
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 99  HPFIKTVGM 107
>NP_055523
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    HPSLKTKAM 9
            HP L  KA+
Sbjct: 1491 HPKLLAKAL 1499
>NP_001015001
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 99  HPFIKTVGM 107
>NP_001816
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 100 HPFIKTVGM 108
>NP_689689
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   HPSLKT 6
           HP LKT
Sbjct: 226 HPCLKT 231
>NP_055318
          Length = 2785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    PSLKTKA 8
            PS++TKA
Sbjct: 2146 PSIETKA 2152
>XP_006719769
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    HPSLKTKAM 9
            HP L  KA+
Sbjct: 1491 HPKLLAKAL 1499
>XP_006719406
          Length = 2380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    PSLKTKA 8
            PS++TKA
Sbjct: 2146 PSIETKA 2152
>XP_005248477
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 217 HPFIKTVGM 225
>XP_006712789
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HPSLKTKAM 9
           HP+L+T  +
Sbjct: 304 HPALRTPGL 312
>XP_005270533
          Length = 126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  HPSLKTKAM 9
          +P+LK KA+
Sbjct: 12 NPTLKDKAL 20
>NP_001021100
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   PSLKTKA 8
           PSL TKA
Sbjct: 714 PSLHTKA 720
>NP_997204
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   PSLKTKAM 9
           P+LKTK +
Sbjct: 180 PTLKTKLL 187
>NP_001093206
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 100 HPFIKTVGM 108
>NP_001093205
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HPSLKTKAM 9
           HP +KT  M
Sbjct: 100 HPFIKTVGM 108
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.116    0.332 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 549,335
Number of extensions: 1010
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package