Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              20     509
XP_005250103                                                           20     509
XP_005250102                                                           20     509
NP_004981                                                              17    2528
XP_006719461                                                           17    2528
NP_940912                                                              16    5631
NP_839955                                                              16    5631
NP_001020095                                                           16    5631
XP_005265807                                                           16    5631
XP_006714105                                                           16    5631
XP_005265805                                                           16    5631
XP_005265804                                                           16    5631
NP_001073978                                                           16    5631
NP_060731                                                              16    5631
NP_940906                                                              16    5631
NP_689524                                                              16    7355
NP_001035700                                                           16    7355
NP_078856                                                              16    7355
NP_954981                                                              16    7355
NP_001135836                                                           15    9605
NP_037470                                                              15    9605
NP_570139                                                              15    9605
NP_001161052                                                           15    9605
NP_055663                                                              15    9605
NP_056996                                                              15    9605
NP_113655                                                              15    9605
NP_001128248                                                           15    9605
NP_001128247                                                           15    9605
NP_722577                                                              15    9605
NP_001095137                                                           15    9605
NP_085076                                                              15    9605
NP_001005417                                                           15    9605
NP_065907                                                              15    9605
NP_003492                                                              15    9605
NP_001243497                                                           15    9605
NP_001138641                                                           15    9605
NP_001138640                                                           15    9605
NP_001245355                                                           15    9605
NP_001245357                                                           15    9605
NP_003771                                                              15    9605
NP_003612                                                              15    9605
NP_001243498                                                           15    9605
XP_005255055                                                           15    9605
XP_005255054                                                           15    9605
XP_005266419                                                           15    9605
XP_006718728                                                           15    9605
XP_005274241                                                           15    9605
XP_005274240                                                           15    9605
XP_005274239                                                           15    9605
XP_006718436                                                           15    9605
XP_006718435                                                           15    9605
XP_005253274                                                           15    9605
XP_006718416                                                           15    9605
XP_006718415                                                           15    9605
XP_006718414                                                           15    9605
XP_006718413                                                           15    9605
XP_005253234                                                           15    9605
XP_006718412                                                           15    9605
XP_005253233                                                           15    9605
XP_005253232                                                           15    9605
XP_005253231                                                           15    9605
XP_005250985                                                           15    9605
XP_006716634                                                           15    9605
XP_006714863                                                           15    9605
XP_006714862                                                           15    9605
XP_005268578                                                           15    9605
XP_005248070                                                           15    9605
XP_005248069                                                           15    9605
XP_005248068                                                           15    9605
XP_006711080                                                           15    9605
XP_005271361                                                           15    9605
NP_073733                                                              15    9605
>NP_004324
          Length = 766

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LLFVSKFF
Sbjct: 288 LLFVSKFF 295
>XP_005250103
          Length = 758

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LLFVSKFF
Sbjct: 288 LLFVSKFF 295
>XP_005250102
          Length = 767

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LLFVSKFF
Sbjct: 288 LLFVSKFF 295
>NP_004981
          Length = 900

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFVSKFF 9
           +FVSKFF
Sbjct: 659 MFVSKFF 665
>XP_006719461
          Length = 666

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LFVSKFF 9
           +FVSKFF
Sbjct: 425 MFVSKFF 431
>NP_940912
          Length = 1313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F+S F
Sbjct: 77 HLAFISNF 84
>NP_839955
          Length = 879

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 517 FISKFF 522
>NP_001020095
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 532 FISKFF 537
>XP_005265807
          Length = 879

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 517 FISKFF 522
>XP_006714105
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 535 FISKFF 540
>XP_005265805
          Length = 912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 550 FISKFF 555
>XP_005265804
          Length = 912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 550 FISKFF 555
>NP_001073978
          Length = 253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  HLLFVSKFF 9
          +LLFV  FF
Sbjct: 18 YLLFVFNFF 26
>NP_060731
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FVSKFF 9
           F+SKFF
Sbjct: 532 FISKFF 537
>NP_940906
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLFVSKF 8
           LLF+SKF
Sbjct: 95  LLFLSKF 101
>NP_689524
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LLFVSKFF 9
          L+F+S FF
Sbjct: 8  LMFLSSFF 15
>NP_001035700
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           ++FVSK F
Sbjct: 360 IIFVSKMF 367
>NP_078856
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           ++FVSK F
Sbjct: 411 IIFVSKMF 418
>NP_954981
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           H+LF+SK
Sbjct: 135 HVLFLSK 141
>NP_001135836
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LL++++FF
Sbjct: 234 LLYIAQFF 241
>NP_037470
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LL++++FF
Sbjct: 264 LLYIAQFF 271
>NP_570139
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HLLFVSKFF 9
          +L+FV  FF
Sbjct: 11 YLMFVFNFF 19
>NP_001161052
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           H+LF   FF
Sbjct: 315 HVLFEDTFF 323
>NP_055663
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           H+LF   FF
Sbjct: 466 HVLFEDTFF 474
>NP_056996
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LFVSKFF 9
            LF+ KFF
Sbjct: 1391 LFLEKFF 1397
>NP_113655
          Length = 959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 609 LLFLTSFF 616
>NP_001128248
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>NP_001128247
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>NP_722577
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HLLFVSKFF 9
           H L+++ FF
Sbjct: 650 HFLYLATFF 658
>NP_001095137
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           HL ++ K F
Sbjct: 140 HLTYIQKIF 148
>NP_085076
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F S+F
Sbjct: 67 HLAFFSRF 74
>NP_001005417
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>NP_065907
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    HLLFVSK 7
            HLL+VS+
Sbjct: 1071 HLLYVSE 1077
>NP_003492
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           HL ++ K F
Sbjct: 140 HLTYIQKIF 148
>NP_001243497
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 576 HVLHVNKF 583
>NP_001138641
          Length = 997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HLLFVSKFF 9
           H L+++ FF
Sbjct: 780 HFLYLATFF 788
>NP_001138640
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HLLFVSKFF 9
           H L+++ FF
Sbjct: 849 HFLYLATFF 857
>NP_001245355
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 595 LLFLTSFF 602
>NP_001245357
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 633 LLFLTSFF 640
>NP_003771
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>NP_003612
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 688 HVLHVNKF 695
>NP_001243498
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 545 HVLHVNKF 552
>XP_005255055
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           H+LF   FF
Sbjct: 466 HVLFEDTFF 474
>XP_005255054
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           H+LF   FF
Sbjct: 466 HVLFEDTFF 474
>XP_005266419
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LLFVSKFF 9
           LL++++FF
Sbjct: 226 LLYIAQFF 233
>XP_006718728
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274241
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274240
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_005274239
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
>XP_006718436
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HLLFVSKFF 9
          +L+FV  FF
Sbjct: 11 YLMFVFNFF 19
>XP_006718435
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HLLFVSKFF 9
          +L+FV  FF
Sbjct: 21 YLMFVFNFF 29
>XP_005253274
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HLLFVSKFF 9
          +L+FV  FF
Sbjct: 21 YLMFVFNFF 29
>XP_006718416
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 556 HVLHVNKF 563
>XP_006718415
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 611 HVLHVNKF 618
>XP_006718414
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 622 HVLHVNKF 629
>XP_006718413
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 699 HVLHVNKF 706
>XP_005253234
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 688 HVLHVNKF 695
>XP_006718412
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 699 HVLHVNKF 706
>XP_005253233
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 749 HVLHVNKF 756
>XP_005253232
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 760 HVLHVNKF 767
>XP_005253231
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HLLFVSKF 8
           H+L V+KF
Sbjct: 749 HVLHVNKF 756
>XP_005250985
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LFVSKFF 9
            LF+ KFF
Sbjct: 1391 LFLEKFF 1397
>XP_006716634
          Length = 1420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LFVSKFF 9
            LF+ KFF
Sbjct: 1405 LFLEKFF 1411
>XP_006714863
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 571 LLFLTSFF 578
>XP_006714862
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 606 LLFLTSFF 613
>XP_005268578
          Length = 959

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLFVSKFF 9
           LLF++ FF
Sbjct: 609 LLFLTSFF 616
>XP_005248070
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           HL ++ K F
Sbjct: 140 HLTYIQKIF 148
>XP_005248069
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           HL ++ K F
Sbjct: 140 HLTYIQKIF 148
>XP_005248068
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HLLFVSKFF 9
           HL ++ K F
Sbjct: 140 HLTYIQKIF 148
>XP_006711080
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>XP_005271361
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HLLFVSKF 8
          HL F S+F
Sbjct: 38 HLAFFSRF 45
>NP_073733
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLLFVSK 7
           HLLF+S+
Sbjct: 136 HLLFMSQ 142
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.357    0.162    0.525 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 446,716
Number of extensions: 791
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)

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