Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              20     509
NP_542165                                                              17    3301
NP_004631                                                              17    3301
NP_620775                                                              17    4312
XP_005263337                                                           17    4312
NP_002733                                                              16    5631
NP_055062                                                              16    5631
XP_005267916                                                           16    5631
XP_006714485                                                           16    5631
XP_005263418                                                           16    5631
XP_005263417                                                           16    5631
XP_006714484                                                           16    5631
XP_005263416                                                           16    5631
XP_006714483                                                           16    5631
XP_005263415                                                           16    5631
XP_006710602                                                           16    5631
XP_006710601                                                           16    5631
XP_006710598                                                           16    5631
XP_006710597                                                           16    5631
XP_006710596                                                           16    5631
XP_006710595                                                           16    5631
XP_006710594                                                           16    5631
XP_006710593                                                           16    5631
XP_006710592                                                           16    5631
XP_006710591                                                           16    5631
XP_006710590                                                           16    5631
XP_006710589                                                           16    5631
XP_006710588                                                           16    5631
XP_006710587                                                           16    5631
XP_006710586                                                           16    5631
XP_006710585                                                           16    5631
XP_005270755                                                           16    5631
XP_006710584                                                           16    5631
XP_005270754                                                           16    5631
XP_005270753                                                           16    5631
XP_006710583                                                           16    5631
XP_005270752                                                           16    5631
XP_006710582                                                           16    5631
XP_005270751                                                           16    5631
NP_055270                                                              15    9605
NP_663696                                                              15    9605
NP_079380                                                              15    9605
XP_006722169                                                           15    9605
XP_006722168                                                           15    9605
XP_006722167                                                           15    9605
XP_006722166                                                           15    9605
XP_006722164                                                           15    9605
XP_006722163                                                           15    9605
XP_006722162                                                           15    9605
XP_006722161                                                           15    9605
XP_005273009                                                           15    9605
>NP_000312
          Length = 928

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HLDQIMMFS 9
           HLDQIMM S
Sbjct: 699 HLDQIMMCS 707
>NP_542165
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HLDQIMMFS 9
           H  Q+MMFS
Sbjct: 220 HEKQVMMFS 228
>NP_004631
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HLDQIMMFS 9
           H  Q+MMFS
Sbjct: 220 HEKQVMMFS 228
>NP_620775
          Length = 409

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HLDQIMMF 8
           H DQIM F
Sbjct: 105 HSDQIMTF 112
>XP_005263337
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  HLDQIMMF 8
          H DQIM F
Sbjct: 56 HSDQIMTF 63
>NP_002733
          Length = 912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           HLD+I+M
Sbjct: 258 HLDKILM 264
>NP_055062
          Length = 1499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1294 HMDQIM 1299
>XP_005267916
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           HLD+I+M
Sbjct: 266 HLDKILM 272
>XP_006714485
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1380 HMDQIM 1385
>XP_005263418
          Length = 1654

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1449 HMDQIM 1454
>XP_005263417
          Length = 1660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1455 HMDQIM 1460
>XP_006714484
          Length = 1685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1480 HMDQIM 1485
>XP_005263416
          Length = 1693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1488 HMDQIM 1493
>XP_006714483
          Length = 1695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1490 HMDQIM 1495
>XP_005263415
          Length = 1701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    HLDQIM 6
            H+DQIM
Sbjct: 1496 HMDQIM 1501
>XP_006710602
          Length = 7391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3062 HLDALTLFS 3070
>XP_006710601
          Length = 4720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710598
          Length = 7553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3052 HLDALTLFS 3060
>XP_006710597
          Length = 7451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3062 HLDALTLFS 3070
>XP_006710596
          Length = 7512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3011 HLDALTLFS 3019
>XP_006710595
          Length = 7526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3025 HLDALTLFS 3033
>XP_006710594
          Length = 7528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3027 HLDALTLFS 3035
>XP_006710593
          Length = 7539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3038 HLDALTLFS 3046
>XP_006710592
          Length = 7544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3043 HLDALTLFS 3051
>XP_006710591
          Length = 7558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3057 HLDALTLFS 3065
>XP_006710590
          Length = 7563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3062 HLDALTLFS 3070
>XP_006710589
          Length = 7595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3094 HLDALTLFS 3102
>XP_006710588
          Length = 7614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710587
          Length = 7645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710586
          Length = 7645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710585
          Length = 7657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_005270755
          Length = 7663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710584
          Length = 7686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_005270754
          Length = 7694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_005270753
          Length = 7700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710583
          Length = 7702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_005270752
          Length = 7717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_006710582
          Length = 7720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>XP_005270751
          Length = 7723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HLDQIMMFS 9
            HLD + +FS
Sbjct: 3222 HLDALTLFS 3230
>NP_055270
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  HLDQIMMF 8
          HLD  M F
Sbjct: 77 HLDHTMFF 84
>NP_663696
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>NP_079380
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_006722169
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_006722168
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_006722167
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_006722166
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  HLDQIMM 7
          H+D++MM
Sbjct: 62 HVDEMMM 68
>XP_006722164
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_006722163
          Length = 673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 162 HVDEMMM 168
>XP_006722162
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 167 HVDEMMM 173
>XP_006722161
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   HLDQIMM 7
           H+D++MM
Sbjct: 183 HVDEMMM 189
>XP_005273009
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  HLDQIMMF 8
          HLD  M F
Sbjct: 44 HLDHTMFF 51
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.142    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 401,681
Number of extensions: 409
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package