Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     390
NP_001185763                                                           20     390
NP_055459                                                              20     390
XP_006726436                                                           20     390
XP_006726410                                                           20     390
XP_006711784                                                           20     390
XP_006711719                                                           20     390
XP_006711718                                                           20     390
XP_006711717                                                           20     390
XP_006711716                                                           20     390
XP_006711715                                                           20     390
XP_006711714                                                           20     390
XP_006711713                                                           20     390
XP_006711712                                                           20     390
XP_006711711                                                           20     390
XP_006711710                                                           20     390
XP_006711709                                                           20     390
XP_005277503                                                           20     390
XP_005273038                                                           20     390
XP_006711708                                                           20     390
XP_005277500                                                           20     390
XP_006711707                                                           20     390
XP_005277499                                                           20     390
XP_006711706                                                           20     390
XP_006711705                                                           20     390
XP_006711164                                                           20     390
XP_005276114                                                           20     390
XP_006710122                                                           20     390
NP_001139182                                                           16    5631
NP_001278257                                                           16    5631
NP_003156                                                              16    5631
NP_060631                                                              16    5631
NP_001027392                                                           16    5631
NP_002379                                                              16    7355
NP_001257401                                                           16    7355
NP_005326                                                              16    7355
NP_000709                                                              16    7355
NP_001230741                                                           16    7355
XP_006721061                                                           16    7355
XP_006710064                                                           16    7355
NP_001277189                                                           15    9605
NP_055968                                                              15    9605
NP_872407                                                              15    9605
NP_055105                                                              15    9605
NP_001277188                                                           15    9605
NP_001171655                                                           15    9605
NP_000346                                                              15    9605
XP_006717089                                                           15    9605
XP_006717088                                                           15    9605
XP_005248759                                                           15    9605
XP_006715489                                                           15    9605
XP_005248758                                                           15    9605
NP_066960                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2216 HDVLKKART 2224
>NP_001185763
          Length = 2362

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2322 HDVLKKART 2330
>NP_055459
          Length = 2346

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2322 HDVLKKART 2330
>XP_006726436
          Length = 178

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HDVLKKAMT 9
           HDVLKKA T
Sbjct: 100 HDVLKKART 108
>XP_006726410
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2063 HDVLKKART 2071
>XP_006711784
          Length = 178

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HDVLKKAMT 9
           HDVLKKA T
Sbjct: 100 HDVLKKART 108
>XP_006711719
          Length = 2302

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2278 HDVLKKART 2286
>XP_006711718
          Length = 1436

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 1329 HDVLKKART 1337
>XP_006711717
          Length = 2385

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2278 HDVLKKART 2286
>XP_006711716
          Length = 2411

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2387 HDVLKKART 2395
>XP_006711715
          Length = 2428

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2321 HDVLKKART 2329
>XP_006711714
          Length = 2429

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2322 HDVLKKART 2330
>XP_006711713
          Length = 2432

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2325 HDVLKKART 2333
>XP_006711712
          Length = 2473

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2366 HDVLKKART 2374
>XP_006711711
          Length = 2482

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2375 HDVLKKART 2383
>XP_006711710
          Length = 2494

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2387 HDVLKKART 2395
>XP_006711709
          Length = 2495

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2388 HDVLKKART 2396
>XP_005277503
          Length = 2498

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2485 HDVLKKART 2493
>XP_005273038
          Length = 2509

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2485 HDVLKKART 2493
>XP_006711708
          Length = 2512

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2405 HDVLKKART 2413
>XP_005277500
          Length = 2525

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2485 HDVLKKART 2493
>XP_006711707
          Length = 2553

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2446 HDVLKKART 2454
>XP_005277499
          Length = 2561

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2485 HDVLKKART 2493
>XP_006711706
          Length = 2591

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2484 HDVLKKART 2492
>XP_006711705
          Length = 2592

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2485 HDVLKKART 2493
>XP_006711164
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HDVLKKAMT 9
            HDVLKKA T
Sbjct: 2063 HDVLKKART 2071
>XP_005276114
          Length = 134

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  HDVLKKAMT 9
          HDVLKKA T
Sbjct: 70 HDVLKKART 78
>XP_006710122
          Length = 126

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   HDVLKKAMT 9
           HDVLKKA T
Sbjct: 100 HDVLKKART 108
>NP_001139182
          Length = 324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   HDVLKKA 7
           HD LKKA
Sbjct: 154 HDPLKKA 160
>NP_001278257
          Length = 187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  HDVLKKA 7
          HD LKKA
Sbjct: 17 HDPLKKA 23
>NP_003156
          Length = 603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HDVLKK 6
          HDV+KK
Sbjct: 16 HDVIKK 21
>NP_060631
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HDVLKKAMT 9
           H VL+KA T
Sbjct: 203 HQVLRKANT 211
>NP_001027392
          Length = 594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HDVLKK 6
          HDV+KK
Sbjct: 16 HDVIKK 21
>NP_002379
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HDVLKKAM 8
           HD +KKA+
Sbjct: 355 HDYVKKAI 362
>NP_001257401
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HDVLKKAM 8
           HD +KKA+
Sbjct: 320 HDYVKKAI 327
>NP_005326
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  HDVLKK 6
          HDVL+K
Sbjct: 65 HDVLRK 70
>NP_000709
          Length = 2339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLKKAMT 9
           DVLK+A T
Sbjct: 414 DVLKRAAT 421
>NP_001230741
          Length = 2237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DVLKKAMT 9
           DVLK+A T
Sbjct: 414 DVLKRAAT 421
>XP_006721061
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HDVLKKAM 8
           HD LK+A+
Sbjct: 280 HDPLKRAL 287
>XP_006710064
          Length = 688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HDVLKKAM 8
           HD LK+A+
Sbjct: 280 HDPLKRAL 287
>NP_001277189
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 573 HSVLKKTL 580
>NP_055968
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 573 HSVLKKTL 580
>NP_872407
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HDVLKKA 7
           HDV K+A
Sbjct: 420 HDVAKRA 426
>NP_055105
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DVLKKAM 8
           DV+KK+M
Sbjct: 883 DVIKKSM 889
>NP_001277188
          Length = 1951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 485 HSVLKKTL 492
>NP_001171655
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DVLKKA 7
           DVLKKA
Sbjct: 330 DVLKKA 335
>NP_000346
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DVLKKA 7
           DVLKKA
Sbjct: 357 DVLKKA 362
>XP_006717089
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DVLKKAM 8
           DV+KK+M
Sbjct: 438 DVIKKSM 444
>XP_006717088
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   DVLKKAM 8
           DV+KK+M
Sbjct: 809 DVIKKSM 815
>XP_005248759
          Length = 1951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 485 HSVLKKTL 492
>XP_006715489
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 573 HSVLKKTL 580
>XP_005248758
          Length = 2039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HDVLKKAM 8
           H VLKK +
Sbjct: 573 HSVLKKTL 580
>NP_066960
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  HDVLKKAM 8
          HD + KAM
Sbjct: 49 HDTMLKAM 56
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.125    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,121
Number of extensions: 648
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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