Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              22     134
NP_671714                                                              22     134
XP_006715890                                                           22     134
XP_005250160                                                           22     134
XP_005250159                                                           22     134
NP_954712                                                              16    7355
NP_002007                                                              16    7355
NP_997192                                                              16    7355
NP_055178                                                              16    7355
NP_001264984                                                           16    7355
NP_009185                                                              16    7355
NP_065114                                                              16    7355
NP_006769                                                              16    7355
XP_006721827                                                           16    7355
XP_006721826                                                           16    7355
XP_006721825                                                           16    7355
XP_005266395                                                           16    7355
XP_006717380                                                           16    7355
NP_439893                                                              16    7355
NP_000149                                                              15    9605
NP_079321                                                              15    9605
NP_003102                                                              15    9605
NP_001128360                                                           15    9605
NP_001017371                                                           15    9605
NP_001166183                                                           15    9605
NP_001129666                                                           15    9605
NP_001129665                                                           15    9605
NP_001129157                                                           15    9605
NP_733779                                                              15    9605
NP_055309                                                              15    9605
NP_008861                                                              15    9605
NP_996844                                                              15    9605
XP_005261808                                                           15    9605
XP_006721103                                                           15    9605
XP_005255314                                                           15    9605
XP_006721102                                                           15    9605
XP_005255313                                                           15    9605
XP_005255312                                                           15    9605
XP_006721101                                                           15    9605
XP_005255311                                                           15    9605
XP_005255310                                                           15    9605
XP_006720568                                                           15    9605
XP_005254438                                                           15    9605
XP_006715677                                                           15    9605
XP_005262832                                                           15    9605
NP_002335                                                              15    9605
NP_055744                                                              15    9605
>NP_005742
          Length = 3907

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HAQMQSSDG 9
            HAQ+QSSDG
Sbjct: 3323 HAQLQSSDG 3331
>NP_671714
          Length = 3899

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HAQMQSSDG 9
            HAQ+QSSDG
Sbjct: 3315 HAQLQSSDG 3323
>XP_006715890
          Length = 3860

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HAQMQSSDG 9
            HAQ+QSSDG
Sbjct: 3276 HAQLQSSDG 3284
>XP_005250160
          Length = 3939

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HAQMQSSDG 9
            HAQ+QSSDG
Sbjct: 3355 HAQLQSSDG 3363
>XP_005250159
          Length = 3952

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    HAQMQSSDG 9
            HAQ+QSSDG
Sbjct: 3368 HAQLQSSDG 3376
>NP_954712
          Length = 1090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HAQMQSS 7
           HAQ+QS+
Sbjct: 742 HAQLQSA 748
>NP_002007
          Length = 4061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    HAQMQSSD 8
            H Q+QS+D
Sbjct: 2008 HHQLQSAD 2015
>NP_997192
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AQMQSSDG 9
           AQ+++SDG
Sbjct: 315 AQLRASDG 322
>NP_055178
          Length = 4579

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HAQMQSSDG 9
            H  +QSS+G
Sbjct: 1139 HTLLQSSEG 1147
>NP_001264984
          Length = 4432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HAQMQSSDG 9
            H  +QSS+G
Sbjct: 992  HTLLQSSEG 1000
>NP_009185
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   HAQMQSSDG 9
           H Q Q++DG
Sbjct: 268 HLQEQANDG 276
>NP_065114
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QMQSSDG 9
           ++QSSDG
Sbjct: 170 ELQSSDG 176
>NP_006769
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AQMQSSDG 9
           AQ++S DG
Sbjct: 205 AQLESQDG 212
>XP_006721827
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HAQMQSS 7
           HAQ+QS+
Sbjct: 539 HAQLQSA 545
>XP_006721826
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HAQMQSS 7
           HAQ+QS+
Sbjct: 539 HAQLQSA 545
>XP_006721825
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HAQMQSS 7
           HAQ+QS+
Sbjct: 723 HAQLQSA 729
>XP_005266395
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HAQMQSSDG 9
            H  +QSS+G
Sbjct: 1148 HTLLQSSEG 1156
>XP_006717380
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AQMQSSDG 9
           AQ+++SDG
Sbjct: 315 AQLRASDG 322
>NP_439893
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AQMQSSDG 9
           AQ++S DG
Sbjct: 205 AQLESQDG 212
>NP_000149
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA   S+DG
Sbjct: 291 HASKNSADG 299
>NP_079321
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HAQMQS 6
           HAQMQ+
Sbjct: 162 HAQMQA 167
>NP_003102
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QMQSSDG 9
           Q+QS+DG
Sbjct: 175 QIQSADG 181
>NP_001128360
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QMQSSDG 9
          QM+SS+G
Sbjct: 22 QMESSEG 28
>NP_001017371
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QMQSSDG 9
           Q+QS+DG
Sbjct: 107 QIQSADG 113
>NP_001166183
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QMQSSDG 9
           Q+QS+DG
Sbjct: 172 QIQSADG 178
>NP_001129666
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HAQMQSSD 8
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
>NP_001129665
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HAQMQSSD 8
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
>NP_001129157
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA M  S+G
Sbjct: 189 HAAMDGSEG 197
>NP_733779
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QMQSSDG 9
          ++QSSDG
Sbjct: 5  KLQSSDG 11
>NP_055309
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 490 HPQMQAPSG 498
>NP_008861
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  QMQSSDG 9
          ++QSSDG
Sbjct: 5  KLQSSDG 11
>NP_996844
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA M  S+G
Sbjct: 189 HAAMDGSEG 197
>XP_005261808
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HAQMQS 6
           HAQMQ+
Sbjct: 162 HAQMQA 167
>XP_006721103
          Length = 1597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 458 HPQMQAPSG 466
>XP_005255314
          Length = 1709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 237 HPQMQAPSG 245
>XP_006721102
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 348 HPQMQAPSG 356
>XP_005255313
          Length = 1822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 458 HPQMQAPSG 466
>XP_005255312
          Length = 1871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 458 HPQMQAPSG 466
>XP_006721101
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 458 HPQMQAPSG 466
>XP_005255311
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 490 HPQMQAPSG 498
>XP_005255310
          Length = 1919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           H QMQ+  G
Sbjct: 458 HPQMQAPSG 466
>XP_006720568
          Length = 771

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA M  S+G
Sbjct: 189 HAAMDGSEG 197
>XP_005254438
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA M  S+G
Sbjct: 189 HAAMDGSEG 197
>XP_006715677
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QMQSSDG 9
           Q+Q+SDG
Sbjct: 241 QIQTSDG 247
>XP_005262832
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HAQMQSSDG 9
           HA++ + DG
Sbjct: 174 HARLSADDG 182
>NP_002335
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HAQMQSSDG 9
           HA M  S+G
Sbjct: 189 HAAMDGSEG 197
>NP_055744
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  HAQMQSSD 8
          H +MQS+D
Sbjct: 65 HNRMQSTD 72
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.108    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,125
Number of extensions: 804
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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