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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           23      60
NP_036462                                                              23      60
NP_001243397                                                           23      60
XP_005269721                                                           23      60
NP_001092882                                                           21     175
NP_006757                                                              21     175
NP_001092883                                                           21     175
XP_005273706                                                           21     175
XP_006710675                                                           17    3301
XP_006710674                                                           17    3301
XP_006710672                                                           17    3301
NP_000501                                                              17    4312
NP_001018090                                                           17    4312
NP_056140                                                              16    5631
NP_067643                                                              16    5631
NP_066943                                                              15    9605
XP_006724690                                                           15    9605
XP_006724689                                                           15    9605
XP_006724688                                                           15    9605

>NP_001243398
          Length = 1781

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HANMMYTAP 9
            H NMMYTAP
Sbjct: 1751 HGNMMYTAP 1759



>NP_036462
          Length = 2073

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HANMMYTAP 9
            H NMMYTAP
Sbjct: 2043 HGNMMYTAP 2051



>NP_001243397
          Length = 1890

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HANMMYTAP 9
            H NMMYTAP
Sbjct: 1860 HGNMMYTAP 1868



>XP_005269721
          Length = 2073

 Score = 22.7 bits (47), Expect =    60
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    HANMMYTAP 9
            H NMMYTAP
Sbjct: 2043 HGNMMYTAP 2051



>NP_001092882
          Length = 2004

 Score = 21.2 bits (43), Expect =   175
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HANMMYTAP 9
            H NMMYT P
Sbjct: 1973 HGNMMYTGP 1981



>NP_006757
          Length = 2004

 Score = 21.2 bits (43), Expect =   175
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HANMMYTAP 9
            H NMMYT P
Sbjct: 1973 HGNMMYTGP 1981



>NP_001092883
          Length = 2004

 Score = 21.2 bits (43), Expect =   175
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HANMMYTAP 9
            H NMMYT P
Sbjct: 1973 HGNMMYTGP 1981



>XP_005273706
          Length = 1997

 Score = 21.2 bits (43), Expect =   175
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    HANMMYTAP 9
            H NMMYT P
Sbjct: 1966 HGNMMYTGP 1974



>XP_006710675
          Length = 783

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HANMMYTAP 9
           H N+ YT P
Sbjct: 721 HKNLTYTQP 729



>XP_006710674
          Length = 1134

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    HANMMYTAP 9
            H N+ YT P
Sbjct: 1072 HKNLTYTQP 1080



>XP_006710672
          Length = 1563

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    HANMMYTAP 9
            H N+ YT P
Sbjct: 1501 HKNLTYTQP 1509



>NP_000501
          Length = 129

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HANMMYTAP 9
          HA+ +YT P
Sbjct: 87 HADSLYTYP 95



>NP_001018090
          Length = 129

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  HANMMYTAP 9
          HA+ +YT P
Sbjct: 87 HADSLYTYP 95



>NP_056140
          Length = 2266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    HANMMYT 7
            HAN+ YT
Sbjct: 2155 HANIAYT 2161



>NP_067643
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HANMMYTAP 9
           HA   Y+AP
Sbjct: 587 HARQRYSAP 595



>NP_066943
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   HANMMYTAP 9
           H N MY  P
Sbjct: 316 HLNDMYAPP 324



>XP_006724690
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   HANMMYTAP 9
           H N MY  P
Sbjct: 316 HLNDMYAPP 324



>XP_006724689
          Length = 831

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   HANMMYTAP 9
           H N MY  P
Sbjct: 316 HLNDMYAPP 324



>XP_006724688
          Length = 849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1   HANMMYTAP 9
           H N MY  P
Sbjct: 316 HLNDMYAPP 324



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.120    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 516,706
Number of extensions: 992
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)