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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     509
NP_009297                                                              20     509
NP_005392                                                              18    1482
XP_005255919                                                           17    4312
XP_005255918                                                           17    4312
XP_005255917                                                           17    4312
XP_005255916                                                           17    4312
XP_005275822                                                           17    4312
NP_079174                                                              16    5631
NP_001277260                                                           16    5631
NP_060482                                                              16    5631
NP_001157968                                                           16    5631
NP_005082                                                              16    5631
XP_006722969                                                           16    5631
XP_006722968                                                           16    5631
XP_005259703                                                           16    5631
XP_005247674                                                           16    5631
XP_006713762                                                           16    5631
XP_006713761                                                           16    5631
XP_006713760                                                           16    5631
XP_006713759                                                           16    5631
NP_060808                                                              16    5631
NP_001155000                                                           16    7355
NP_001034842                                                           16    7355
XP_006720777                                                           16    7355
XP_006712079                                                           16    7355
NP_056197                                                              15    9605
XP_005267560                                                           15    9605
XP_005267559                                                           15    9605

>NP_005148
          Length = 1130

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           GV NGALRE
Sbjct: 667 GVPNGALRE 675



>NP_009297
          Length = 1149

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           GV NGALRE
Sbjct: 686 GVPNGALRE 694



>NP_005392
          Length = 1187

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   VSNGALRE 9
           VSNGALR+
Sbjct: 759 VSNGALRQ 766



>XP_005255919
          Length = 1860

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           G+ +GALRE
Sbjct: 457 GLPSGALRE 465



>XP_005255918
          Length = 1949

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           G+ +GALRE
Sbjct: 457 GLPSGALRE 465



>XP_005255917
          Length = 1984

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           G+ +GALRE
Sbjct: 457 GLPSGALRE 465



>XP_005255916
          Length = 2022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           G+ +GALRE
Sbjct: 457 GLPSGALRE 465



>XP_005275822
          Length = 800

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GVSNGALRE 9
           G+ +GALRE
Sbjct: 406 GLPSGALRE 414



>NP_079174
          Length = 801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G S+GALR
Sbjct: 413 GASSGALR 420



>NP_001277260
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G S+GALR
Sbjct: 369 GASSGALR 376



>NP_060482
          Length = 2108

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GVSNGA 6
           GVSNGA
Sbjct: 272 GVSNGA 277



>NP_001157968
          Length = 1854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 824 GMKNGAIR 831



>NP_005082
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           GV+ GALR
Sbjct: 155 GVAQGALR 162



>XP_006722969
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G S+GALR
Sbjct: 369 GASSGALR 376



>XP_006722968
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G S+GALR
Sbjct: 508 GASSGALR 515



>XP_005259703
          Length = 938

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G S+GALR
Sbjct: 550 GASSGALR 557



>XP_005247674
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GVSNGALR 8
          G+ NGA+R
Sbjct: 59 GMKNGAIR 66



>XP_006713762
          Length = 1197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 868 GMKNGAIR 875



>XP_006713761
          Length = 1554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 524 GMKNGAIR 531



>XP_006713760
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 817 GMKNGAIR 824



>XP_006713759
          Length = 1898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 868 GMKNGAIR 875



>NP_060808
          Length = 982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVSNGALR 8
           G+ NGA+R
Sbjct: 824 GMKNGAIR 831



>NP_001155000
          Length = 860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VSNGALRE 9
           +SN A+RE
Sbjct: 658 ISNNAIRE 665



>NP_001034842
          Length = 1958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GVSNGAL 7
           GVSNG L
Sbjct: 597 GVSNGML 603



>XP_006720777
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GVSNGAL 7
          G+SNGA+
Sbjct: 29 GLSNGAM 35



>XP_006712079
          Length = 1683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GVSNGAL 7
           GVSNG L
Sbjct: 355 GVSNGML 361



>NP_056197
          Length = 2610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VSNGALR 8
           VS+GALR
Sbjct: 202 VSDGALR 208



>XP_005267560
          Length = 2563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VSNGALR 8
           VS+GALR
Sbjct: 202 VSDGALR 208



>XP_005267559
          Length = 2610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VSNGALR 8
           VS+GALR
Sbjct: 202 VSDGALR 208



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.130    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 567,025
Number of extensions: 977
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)