Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_951008                                                              19     665
NP_003115                                                              16    5631
NP_689931                                                              16    5631
NP_001272320                                                           16    5631
XP_006718526                                                           16    5631
XP_005273893                                                           16    5631
XP_006718525                                                           16    5631
XP_006718524                                                           16    5631
XP_006718523                                                           16    5631
NP_001094861                                                           16    5631
NP_001166176                                                           16    7355
NP_001036024                                                           16    7355
NP_001409                                                              16    7355
NP_872393                                                              16    7355
XP_006725408                                                           16    7355
XP_006725407                                                           16    7355
XP_006725406                                                           16    7355
XP_006725405                                                           16    7355
XP_006724404                                                           16    7355
XP_006724403                                                           16    7355
XP_005261845                                                           16    7355
XP_005261844                                                           16    7355
XP_005261843                                                           16    7355
XP_005257698                                                           16    7355
XP_005257699                                                           16    7355
XP_006722134                                                           16    7355
XP_005257697                                                           16    7355
XP_006712515                                                           16    7355
XP_006712513                                                           16    7355
XP_006712512                                                           16    7355
XP_006712511                                                           16    7355
XP_006712510                                                           16    7355
XP_006712509                                                           16    7355
XP_005246533                                                           16    7355
XP_006712508                                                           16    7355
NP_115893                                                              16    7355
NP_060228                                                              16    7355
NP_009075                                                              16    7355
NP_067069                                                              16    7355
NP_899236                                                              15    9605
NP_001714                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_054742                                                              15    9605
NP_115997                                                              15    9605
NP_065779                                                              15    9605
NP_060267                                                              15    9605
XP_005259650                                                           15    9605
XP_005273841                                                           15    9605
XP_005273840                                                           15    9605
XP_005273839                                                           15    9605
XP_006718500                                                           15    9605
XP_006715232                                                           15    9605
XP_005249383                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
NP_612480                                                              15    9605
>NP_951008
          Length = 1086

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1    GVRQIRLPA 9
            G++QIRLPA
Sbjct: 1060 GLKQIRLPA 1068
>NP_003115
          Length = 261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GVRQIRLPA 9
          G+R +R+PA
Sbjct: 60 GLRVVRVPA 68
>NP_689931
          Length = 955

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR  RLP+
Sbjct: 312 GVRTTRLPS 320
>NP_001272320
          Length = 277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  VRQIRLPA 9
          VRQ+R+P+
Sbjct: 5  VRQLRVPS 12
>XP_006718526
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GVRQIRLPA 9
          GVR  RLP+
Sbjct: 29 GVRTTRLPS 37
>XP_005273893
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR  RLP+
Sbjct: 182 GVRTTRLPS 190
>XP_006718525
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR  RLP+
Sbjct: 312 GVRTTRLPS 320
>XP_006718524
          Length = 912

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR  RLP+
Sbjct: 269 GVRTTRLPS 277
>XP_006718523
          Length = 947

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR  RLP+
Sbjct: 312 GVRTTRLPS 320
>NP_001094861
          Length = 592

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GVRQIRL 7
           G+RQIRL
Sbjct: 316 GLRQIRL 322
>NP_001166176
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVRQIRLP 8
           GVR++R P
Sbjct: 567 GVREMRAP 574
>NP_001036024
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVRQIRLP 8
           GVR++R P
Sbjct: 529 GVREMRAP 536
>NP_001409
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVRQIRLP 8
           GVR++R P
Sbjct: 567 GVREMRAP 574
>NP_872393
          Length = 3234

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3039 GLRQLRRP 3046
>XP_006725408
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006725407
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006725406
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006725405
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006724404
          Length = 1442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RQIRLPA 9
            +Q+RLPA
Sbjct: 1020 QQVRLPA 1026
>XP_006724403
          Length = 2449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RQIRLPA 9
           +Q+RLPA
Sbjct: 901 QQVRLPA 907
>XP_005261845
          Length = 2568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RQIRLPA 9
            +Q+RLPA
Sbjct: 1020 QQVRLPA 1026
>XP_005261844
          Length = 2568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RQIRLPA 9
            +Q+RLPA
Sbjct: 1020 QQVRLPA 1026
>XP_005261843
          Length = 2568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RQIRLPA 9
            +Q+RLPA
Sbjct: 1020 QQVRLPA 1026
>XP_005257698
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_005257699
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006722134
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_005257697
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>XP_006712515
          Length = 3232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3037 GLRQLRRP 3044
>XP_006712513
          Length = 3220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3025 GLRQLRRP 3032
>XP_006712512
          Length = 3237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3042 GLRQLRRP 3049
>XP_006712511
          Length = 3256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3061 GLRQLRRP 3068
>XP_006712510
          Length = 3305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3110 GLRQLRRP 3117
>XP_006712509
          Length = 3319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3124 GLRQLRRP 3131
>XP_005246533
          Length = 3323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3128 GLRQLRRP 3135
>XP_006712508
          Length = 3324

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3129 GLRQLRRP 3136
>NP_115893
          Length = 3258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GVRQIRLP 8
            G+RQ+R P
Sbjct: 3063 GLRQLRRP 3070
>NP_060228
          Length = 394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GVRQIRL 7
          G+RQ+RL
Sbjct: 88 GIRQMRL 94
>NP_009075
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           GVR +R PA
Sbjct: 162 GVRFLRCPA 170
>NP_067069
          Length = 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GVRQIRLP 8
          G+ QI+LP
Sbjct: 50 GLEQIKLP 57
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1087 IRQIRTP 1093
>NP_001714
          Length = 2649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRQIRLP 8
           +RQIR P
Sbjct: 761 IRQIRTP 767
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRQIRLP 8
           +RQIR P
Sbjct: 761 IRQIRTP 767
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1265 IRQIRTP 1271
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1127 IRQIRTP 1133
>NP_054742
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GVRQIRLP 8
           GVR  RLP
Sbjct: 439 GVRLARLP 446
>NP_115997
          Length = 2567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QIRLPA 9
            Q+RLPA
Sbjct: 1020 QVRLPA 1025
>NP_065779
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GVRQIRLPA 9
          GVR+ R+P+
Sbjct: 10 GVRRSRVPS 18
>NP_060267
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   GVRQIRL 7
           G+R++RL
Sbjct: 276 GIREVRL 282
>XP_005259650
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   GVRQIRL 7
           G+R++RL
Sbjct: 128 GIREVRL 134
>XP_005273841
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           G+R + LPA
Sbjct: 195 GLRPLELPA 203
>XP_005273840
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           G+R + LPA
Sbjct: 195 GLRPLELPA 203
>XP_005273839
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           G+R + LPA
Sbjct: 195 GLRPLELPA 203
>XP_006718500
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           G+R + LPA
Sbjct: 195 GLRPLELPA 203
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1087 IRQIRTP 1093
>XP_005249383
          Length = 3186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VRQIRLP 8
           +RQIR P
Sbjct: 761 IRQIRTP 767
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1087 IRQIRTP 1093
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1113 IRQIRTP 1119
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1120 IRQIRTP 1126
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1127 IRQIRTP 1133
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1160 IRQIRTP 1166
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1203 IRQIRTP 1209
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1265 IRQIRTP 1271
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1277 IRQIRTP 1283
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VRQIRLP 8
            +RQIR P
Sbjct: 1298 IRQIRTP 1304
>NP_612480
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GVRQIRLPA 9
           G+R + LPA
Sbjct: 195 GLRPLELPA 203
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.149    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 524,385
Number of extensions: 965
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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