Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     509
NP_115543                                                              17    2528
XP_006721041                                                           17    2528
XP_006721040                                                           17    2528
XP_005255739                                                           17    2528
NP_660159                                                              16    5631
XP_006715412                                                           16    5631
NP_001077430                                                           16    7355
NP_000426                                                              16    7355
NP_775907                                                              16    7355
NP_001001344                                                           16    7355
NP_068768                                                              16    7355
NP_009187                                                              16    7355
NP_619636                                                              16    7355
NP_714921                                                              16    7355
XP_005274750                                                           16    7355
XP_005274749                                                           16    7355
XP_005274748                                                           16    7355
XP_005274747                                                           16    7355
XP_006724886                                                           16    7355
XP_005274746                                                           16    7355
XP_005258866                                                           16    7355
XP_005259981                                                           16    7355
XP_006718490                                                           16    7355
NP_001138683                                                           16    7355
NP_115758                                                              15    9605
NP_055945                                                              15    9605
NP_001137282                                                           15    9605
NP_001268451                                                           15    9605
NP_001268449                                                           15    9605
NP_877954                                                              15    9605
NP_001268450                                                           15    9605
NP_115874                                                              15    9605
NP_001269285                                                           15    9605
NP_872114                                                              15    9605
NP_599028                                                              15    9605
NP_439897                                                              15    9605
NP_006366                                                              15    9605
NP_001268665                                                           15    9605
NP_001105                                                              15    9605
NP_001269286                                                           15    9605
XP_005262412                                                           15    9605
XP_005262411                                                           15    9605
XP_005260916                                                           15    9605
XP_005255842                                                           15    9605
XP_006721191                                                           15    9605
XP_005255841                                                           15    9605
XP_005255840                                                           15    9605
XP_005255839                                                           15    9605
XP_005255837                                                           15    9605
XP_005255838                                                           15    9605
XP_005255836                                                           15    9605
XP_003961007                                                           15    9605
>NP_004251
          Length = 1208

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GVLVEFNEL 9
            GVLVEF+EL
Sbjct: 1025 GVLVEFSEL 1033
>NP_115543
          Length = 813

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G L+EFNE
Sbjct: 600 GELIEFNE 607
>XP_006721041
          Length = 680

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G L+EFNE
Sbjct: 467 GELIEFNE 474
>XP_006721040
          Length = 661

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G L+EFNE
Sbjct: 448 GELIEFNE 455
>XP_005255739
          Length = 823

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G L+EFNE
Sbjct: 610 GELIEFNE 617
>NP_660159
          Length = 617

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVLVEFNEL 9
           G+LV  NEL
Sbjct: 165 GLLVSLNEL 173
>XP_006715412
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVLVEFNEL 9
           G+LV  NEL
Sbjct: 165 GLLVSLNEL 173
>NP_001077430
          Length = 1523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G+L +FNE
Sbjct: 276 GLLCQFNE 283
>NP_000426
          Length = 2321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    GVLVEFNE 8
            GVL E NE
Sbjct: 1154 GVLCEINE 1161
>NP_775907
          Length = 1518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G+L +FNE
Sbjct: 276 GLLCQFNE 283
>NP_001001344
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>NP_068768
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>NP_009187
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GVLVEFNEL 9
          G+L  FNE+
Sbjct: 88 GLLASFNEV 96
>NP_619636
          Length = 760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GVLVEFNEL 9
           GVL +FN L
Sbjct: 241 GVLYDFNGL 249
>NP_714921
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VLVEFNEL 9
           +++EFNEL
Sbjct: 106 LVMEFNEL 113
>XP_005274750
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_005274749
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_005274748
          Length = 1206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_005274747
          Length = 1220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_006724886
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_005274746
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           GVL++ N+L
Sbjct: 229 GVLIQANDL 237
>XP_005258866
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GVLVEFNE 8
           G+L +FNE
Sbjct: 276 GLLCQFNE 283
>XP_005259981
          Length = 2269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    GVLVEFNE 8
            GVL E NE
Sbjct: 1102 GVLCEINE 1109
>XP_006718490
          Length = 635

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GVLVEFNEL 9
          G+L  FNE+
Sbjct: 88 GLLASFNEV 96
>NP_001138683
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GVLVEFNEL 9
          G+L  FNE+
Sbjct: 66 GLLASFNEV 74
>NP_115758
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV FN+L
Sbjct: 442 ILVAFNDL 449
>NP_055945
          Length = 1266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G++ E+N++
Sbjct: 121 GIIAEYNKI 129
>NP_001137282
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VLVEFNEL 9
          V VEFN+L
Sbjct: 60 VSVEFNKL 67
>NP_001268451
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>NP_001268449
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>NP_877954
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>NP_001268450
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>NP_115874
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>NP_001269285
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F +L
Sbjct: 419 GMLIQFRDL 427
>NP_872114
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F ++
Sbjct: 327 GILIQFEQI 335
>NP_599028
          Length = 663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F +L
Sbjct: 419 GMLIQFRDL 427
>NP_439897
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F +L
Sbjct: 419 GMLIQFRDL 427
>NP_006366
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F ++
Sbjct: 298 GILIQFEQI 306
>NP_001268665
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F ++
Sbjct: 298 GILIQFEQI 306
>NP_001105
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>NP_001269286
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F +L
Sbjct: 118 GMLIQFRDL 126
>XP_005262412
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F ++
Sbjct: 327 GILIQFEQI 335
>XP_005262411
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+L++F ++
Sbjct: 327 GILIQFEQI 335
>XP_005260916
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VLVEFNEL 9
           +LV+F EL
Sbjct: 121 ILVDFKEL 128
>XP_005255842
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 762 GVMVEFS 768
>XP_006721191
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 790 GVMVEFS 796
>XP_005255841
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255840
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255839
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255837
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255838
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255836
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GVLVEFN 7
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_003961007
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 8/9 (88%)

Query: 1   GVLVEFNEL 9
           G+++E+N +
Sbjct: 409 GIIIEWNRM 417
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.150    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 500,502
Number of extensions: 807
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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