Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           18    1935
NP_858045                                                              18    1935
NP_006525                                                              18    1935
NP_001167559                                                           18    1935
NP_079421                                                              18    1935
XP_005270233                                                           18    1935
XP_005270232                                                           18    1935
XP_005270231                                                           18    1935
XP_005270230                                                           18    1935
XP_005270229                                                           18    1935
XP_005270228                                                           18    1935
NP_490597                                                              16    5631
NP_055114                                                              16    5631
NP_066564                                                              16    5631
XP_006721881                                                           16    5631
XP_006721880                                                           16    5631
>NP_001167558
          Length = 1423

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVETSLLST 9
           GV TSLLST
Sbjct: 532 GVGTSLLST 540
>NP_858045
          Length = 1424

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVETSLLST 9
           GV TSLLST
Sbjct: 532 GVGTSLLST 540
>NP_006525
          Length = 1420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVETSLLST 9
           GV TSLLST
Sbjct: 532 GVGTSLLST 540
>NP_001167559
          Length = 1415

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GVETSLLST 9
           GV TSLLST
Sbjct: 542 GVGTSLLST 550
>NP_079421
          Length = 1665

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 987 GVDTSLLSS 995
>XP_005270233
          Length = 927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 249 GVDTSLLSS 257
>XP_005270232
          Length = 1535

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 988 GVDTSLLSS 996
>XP_005270231
          Length = 1627

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 949 GVDTSLLSS 957
>XP_005270230
          Length = 1627

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 949 GVDTSLLSS 957
>XP_005270229
          Length = 1637

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 988 GVDTSLLSS 996
>XP_005270228
          Length = 1666

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   GVETSLLST 9
           GV+TSLLS+
Sbjct: 988 GVDTSLLSS 996
>NP_490597
          Length = 1362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GVETSLLST 9
          G+ETS +ST
Sbjct: 20 GLETSQMST 28
>NP_055114
          Length = 722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GVETSLLST 9
          G+ETS +ST
Sbjct: 20 GLETSQMST 28
>NP_066564
          Length = 837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GVETSLLS 8
           G ETSLLS
Sbjct: 474 GPETSLLS 481
>XP_006721881
          Length = 477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GVETSLLS 8
           G ETSLLS
Sbjct: 113 GPETSLLS 120
>XP_006721880
          Length = 838

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GVETSLLS 8
           G ETSLLS
Sbjct: 474 GPETSLLS 481
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.117    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,559
Number of extensions: 426
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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