Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_542168                                                              18    1482
NP_004295                                                              18    1482
NP_002825                                                              18    1482
XP_006719590                                                           18    1482
XP_006719589                                                           18    1482
NP_065769                                                              16    5631
NP_001269281                                                           16    5631
NP_112219                                                              16    5631
XP_005272557                                                           16    5631
XP_005272556                                                           16    5631
XP_006722980                                                           16    5631
XP_006722979                                                           16    5631
XP_006721134                                                           16    5631
XP_005255507                                                           16    5631
NP_996763                                                              16    5631
NP_597716                                                              16    7355
XP_005266706                                                           16    7355
XP_005266705                                                           16    7355
XP_006722456                                                           16    7355
XP_006711659                                                           16    7355
XP_005277493                                                           16    7355
XP_005277492                                                           16    7355
XP_005277490                                                           16    7355
XP_005277491                                                           16    7355
XP_005277489                                                           16    7355
NP_003628                                                              16    7355
NP_056493                                                              15    9605
NP_776167                                                              15    9605
NP_116784                                                              15    9605
NP_113660                                                              15    9605
NP_001028850                                                           15    9605
NP_004313                                                              15    9605
NP_001153865                                                           15    9605
NP_001153864                                                           15    9605
NP_001153862                                                           15    9605
NP_001153861                                                           15    9605
XP_006721093                                                           15    9605
XP_006721092                                                           15    9605
XP_006721091                                                           15    9605
XP_006719869                                                           15    9605
XP_006719868                                                           15    9605
XP_005266408                                                           15    9605
XP_005266407                                                           15    9605
XP_005266403                                                           15    9605
XP_006719867                                                           15    9605
XP_006719866                                                           15    9605
XP_005266405                                                           15    9605
XP_005266404                                                           15    9605
XP_005274404                                                           15    9605
XP_006718771                                                           15    9605
XP_006718770                                                           15    9605
XP_005274403                                                           15    9605
XP_006718769                                                           15    9605
XP_005274402                                                           15    9605
XP_005245197                                                           15    9605
XP_005245196                                                           15    9605
>NP_542168
          Length = 460

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GTVLQLRQ 8
           GTVLQL+Q
Sbjct: 207 GTVLQLKQ 214
>NP_004295
          Length = 1620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTVLQLRQA 9
           GTVLQL QA
Sbjct: 446 GTVLQLGQA 454
>NP_002825
          Length = 593

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GTVLQLRQ 8
           GTVLQL+Q
Sbjct: 207 GTVLQLKQ 214
>XP_006719590
          Length = 559

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GTVLQLRQ 8
           GTVLQL+Q
Sbjct: 207 GTVLQLKQ 214
>XP_006719589
          Length = 597

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GTVLQLRQ 8
           GTVLQL+Q
Sbjct: 207 GTVLQLKQ 214
>NP_065769
          Length = 1352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTVLQLRQA 9
           GTV +LR+A
Sbjct: 344 GTVARLREA 352
>NP_001269281
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 260 GTTFQLRQ 267
>NP_112219
          Length = 1103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 773 GTTFQLRQ 780
>XP_005272557
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 294 GTTFQLRQ 301
>XP_005272556
          Length = 626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 296 GTTFQLRQ 303
>XP_006722980
          Length = 784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 405 GTTFQLRQ 412
>XP_006722979
          Length = 1103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GTVLQLRQ 8
           GT  QLRQ
Sbjct: 773 GTTFQLRQ 780
>XP_006721134
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GTVLQLRQA 9
          GTV +LR+A
Sbjct: 81 GTVARLREA 89
>XP_005255507
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GTVLQLRQA 9
          GTV +LR+A
Sbjct: 81 GTVARLREA 89
>NP_996763
          Length = 315

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTVLQLRQA 9
           GTVLQ+  A
Sbjct: 224 GTVLQMHSA 232
>NP_597716
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVLQLRQ 8
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>XP_005266706
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TVLQLRQ 8
          TVLQL+Q
Sbjct: 20 TVLQLKQ 26
>XP_005266705
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVLQLRQ 8
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>XP_006722456
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TVLQLRQ 8
           TVLQL+Q
Sbjct: 211 TVLQLKQ 217
>XP_006711659
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTVLQLRQA 9
           G+VLQL +A
Sbjct: 974 GSVLQLTEA 982
>XP_005277493
          Length = 1105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1033 GSVLQLTEA 1041
>XP_005277492
          Length = 1119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1047 GSVLQLTEA 1055
>XP_005277490
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1071 GSVLQLTEA 1079
>XP_005277491
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1071 GSVLQLTEA 1079
>XP_005277489
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1109 GSVLQLTEA 1117
>NP_003628
          Length = 1167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GTVLQLRQA 9
            G+VLQL +A
Sbjct: 1095 GSVLQLTEA 1103
>NP_056493
          Length = 2946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>NP_776167
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GTVLQLR 7
          GTVLQ++
Sbjct: 40 GTVLQIK 46
>NP_116784
          Length = 168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTVLQLRQA 9
           GT  Q+RQ+
Sbjct: 136 GTATQMRQS 144
>NP_113660
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 10 GTLLQLPQ 17
>NP_001028850
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>NP_004313
          Length = 168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTVLQLRQA 9
           GT  Q+RQ+
Sbjct: 136 GTATQMRQS 144
>NP_001153865
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>NP_001153864
          Length = 216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>NP_001153862
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>NP_001153861
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_006721093
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GTVLQLR 7
          GTVLQ++
Sbjct: 40 GTVLQIK 46
>XP_006721092
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTVLQLR 7
           GTVLQ++
Sbjct: 100 GTVLQIK 106
>XP_006721091
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTVLQLR 7
           GTVLQ++
Sbjct: 100 GTVLQIK 106
>XP_006719869
          Length = 2943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_006719868
          Length = 2938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_005266408
          Length = 1934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_005266407
          Length = 2641

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 312 GTVLQL 317
>XP_005266403
          Length = 2941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_006719867
          Length = 2961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_006719866
          Length = 2962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_005266405
          Length = 2964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_005266404
          Length = 2967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTVLQL 6
           GTVLQL
Sbjct: 638 GTVLQL 643
>XP_005274404
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 10 GTLLQLPQ 17
>XP_006718771
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_006718770
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_005274403
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_006718769
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_005274402
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTVLQLRQ 8
          GT+LQL Q
Sbjct: 59 GTLLQLPQ 66
>XP_005245197
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VLQLRQA 9
           +LQ+RQA
Sbjct: 300 ILQMRQA 306
>XP_005245196
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VLQLRQA 9
           +LQ+RQA
Sbjct: 300 ILQMRQA 306
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.134    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 368,822
Number of extensions: 428
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package