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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              19     665
NP_001263689                                                           19     665
NP_001119584                                                           19     665
NP_001119586                                                           19     665
NP_001263625                                                           19     665
NP_001119590                                                           19     665
NP_001263690                                                           19     665
NP_001119585                                                           19     665
NP_001263624                                                           19     665
NP_001119588                                                           19     665
NP_001119587                                                           19     665
NP_001119589                                                           19     665
NP_003142                                                              17    4312
NP_001230764                                                           17    4312
XP_006712782                                                           17    4312
XP_005246874                                                           17    4312
NP_001139281                                                           16    5631
NP_001070654                                                           16    5631
NP_079005                                                              16    5631
XP_006723449                                                           16    5631
NP_612486                                                              16    7355
NP_001035931                                                           16    7355
NP_001035930                                                           16    7355
NP_065779                                                              16    7355
NP_002769                                                              16    7355
XP_005254235                                                           16    7355
XP_005254233                                                           16    7355
XP_005254234                                                           16    7355
XP_005245660                                                           16    7355
NP_001073895                                                           16    7355
NP_001008844                                                           15    9605
NP_004406                                                              15    9605

>NP_000537
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 154 GTRVRAMAI 162



>NP_001263689
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 115 GTRVRAMAI 123



>NP_001119584
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 154 GTRVRAMAI 162



>NP_001119586
          Length = 341

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 154 GTRVRAMAI 162



>NP_001263625
          Length = 302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 115 GTRVRAMAI 123



>NP_001119590
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 115 GTRVRAMAI 123



>NP_001263690
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 115 GTRVRAMAI 123



>NP_001119585
          Length = 346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 154 GTRVRAMAI 162



>NP_001263624
          Length = 307

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTRVRAM I
Sbjct: 115 GTRVRAMAI 123



>NP_001119588
          Length = 209

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVRAMTI 9
          GTRVRAM I
Sbjct: 22 GTRVRAMAI 30



>NP_001119587
          Length = 261

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVRAMTI 9
          GTRVRAM I
Sbjct: 22 GTRVRAMAI 30



>NP_001119589
          Length = 214

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVRAMTI 9
          GTRVRAM I
Sbjct: 22 GTRVRAMAI 30



>NP_003142
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GT V+AM+I
Sbjct: 379 GTNVKAMSI 387



>NP_001230764
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GT V+AM+I
Sbjct: 379 GTNVKAMSI 387



>XP_006712782
          Length = 748

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GT V+AM+I
Sbjct: 379 GTNVKAMSI 387



>XP_005246874
          Length = 757

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GT V+AM+I
Sbjct: 388 GTNVKAMSI 396



>NP_001139281
          Length = 2036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GTRVRAM 7
            G+RVRAM
Sbjct: 1393 GSRVRAM 1399



>NP_001070654
          Length = 2003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GTRVRAM 7
            G+RVRAM
Sbjct: 1360 GSRVRAM 1366



>NP_079005
          Length = 1995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GTRVRAM 7
            G+RVRAM
Sbjct: 1352 GSRVRAM 1358



>XP_006723449
          Length = 2003

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GTRVRAM 7
            G+RVRAM
Sbjct: 1360 GSRVRAM 1366



>NP_612486
          Length = 1227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVRAM 7
           G+R+RAM
Sbjct: 482 GSRIRAM 488



>NP_001035931
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTR+ A+T+
Sbjct: 392 GTRLPALTV 400



>NP_001035930
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTR+ A+T+
Sbjct: 393 GTRLPALTV 401



>NP_065779
          Length = 893

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTRVRAMT 8
           GTR +AMT
Sbjct: 886 GTRPQAMT 893



>NP_002769
          Length = 524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTRVRAMTI 9
           GTR+ A+T+
Sbjct: 390 GTRLPALTV 398



>XP_005254235
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVRAM 7
           G+R+RAM
Sbjct: 483 GSRIRAM 489



>XP_005254233
          Length = 1228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVRAM 7
           G+R+RAM
Sbjct: 483 GSRIRAM 489



>XP_005254234
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVRAM 7
           G+R+RAM
Sbjct: 483 GSRIRAM 489



>XP_005245660
          Length = 1158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTRVRAMTI 9
           G RV A+T+
Sbjct: 306 GARVHALTV 314



>NP_001073895
          Length = 1158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTRVRAMTI 9
           G RV A+T+
Sbjct: 306 GARVHALTV 314



>NP_001008844
          Length = 2272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RVRAMTI 9
           ++RAMTI
Sbjct: 559 KIRAMTI 565



>NP_004406
          Length = 2871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RVRAMTI 9
           ++RAMTI
Sbjct: 559 KIRAMTI 565



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.135    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 259,183
Number of extensions: 283
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)