Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1482
NP_001263689                                                           18    1482
NP_001119584                                                           18    1482
NP_001119586                                                           18    1482
NP_001263625                                                           18    1482
NP_001119590                                                           18    1482
NP_001263690                                                           18    1482
NP_001119585                                                           18    1482
NP_001263624                                                           18    1482
NP_001119588                                                           18    1482
NP_001119587                                                           18    1482
NP_001119589                                                           18    1482
NP_001073906                                                           18    1935
XP_006712470                                                           18    1935
XP_006712469                                                           18    1935
XP_006712468                                                           18    1935
XP_005247054                                                           18    1935
NP_000262                                                              16    5631
NP_055795                                                              16    5631
NP_001273514                                                           16    5631
NP_006310                                                              16    5631
XP_006722542                                                           16    5631
XP_005258336                                                           16    5631
XP_005258335                                                           16    5631
XP_005258334                                                           16    5631
XP_005255095                                                           16    5631
XP_005247964                                                           16    5631
XP_006713889                                                           16    5631
XP_006713888                                                           16    5631
NP_001036097                                                           16    7355
NP_001036098                                                           16    7355
NP_219489                                                              16    7355
NP_690857                                                              16    7355
NP_612361                                                              16    7355
NP_149034                                                              16    7355
NP_001139269                                                           15    9605
NP_001243452                                                           15    9605
NP_060768                                                              15    9605
NP_001240622                                                           15    9605
XP_006724202                                                           15    9605
XP_005256701                                                           15    9605
XP_005256700                                                           15    9605
XP_006721100                                                           15    9605
XP_006721099                                                           15    9605
XP_006721098                                                           15    9605
XP_006721097                                                           15    9605
XP_006721096                                                           15    9605
XP_006721095                                                           15    9605
XP_006721094                                                           15    9605
XP_006710814                                                           15    9605
XP_005271060                                                           15    9605
XP_006710813                                                           15    9605
NP_004131                                                              15    9605
NP_001397                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 154 GTRVRAMAI 162
>NP_001263689
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 115 GTRVRAMAI 123
>NP_001119584
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 154 GTRVRAMAI 162
>NP_001119586
          Length = 341

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 154 GTRVRAMAI 162
>NP_001263625
          Length = 302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 115 GTRVRAMAI 123
>NP_001119590
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 115 GTRVRAMAI 123
>NP_001263690
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 115 GTRVRAMAI 123
>NP_001119585
          Length = 346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 154 GTRVRAMAI 162
>NP_001263624
          Length = 307

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTRVGAMAI 9
           GTRV AMAI
Sbjct: 115 GTRVRAMAI 123
>NP_001119588
          Length = 209

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVGAMAI 9
          GTRV AMAI
Sbjct: 22 GTRVRAMAI 30
>NP_001119587
          Length = 261

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVGAMAI 9
          GTRV AMAI
Sbjct: 22 GTRVRAMAI 30
>NP_001119589
          Length = 214

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GTRVGAMAI 9
          GTRV AMAI
Sbjct: 22 GTRVRAMAI 30
>NP_001073906
          Length = 1413

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GTRVGAMAI 9
           GTR+GA+A+
Sbjct: 713 GTRLGAVAL 721
>XP_006712470
          Length = 1327

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GTRVGAMAI 9
           GTR+GA+A+
Sbjct: 713 GTRLGAVAL 721
>XP_006712469
          Length = 1380

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GTRVGAMAI 9
           GTR+GA+A+
Sbjct: 713 GTRLGAVAL 721
>XP_006712468
          Length = 1413

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GTRVGAMAI 9
           GTR+GA+A+
Sbjct: 713 GTRLGAVAL 721
>XP_005247054
          Length = 1434

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GTRVGAMAI 9
           GTR+GA+A+
Sbjct: 713 GTRLGAVAL 721
>NP_000262
          Length = 1278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    GTRVGA 6
            GTRVGA
Sbjct: 1030 GTRVGA 1035
>NP_055795
          Length = 1186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 88 GTRTGAIRI 96
>NP_001273514
          Length = 168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GTRVGAM 7
          GTR GAM
Sbjct: 15 GTRFGAM 21
>NP_006310
          Length = 213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GTRVGAM 7
          GTR GAM
Sbjct: 60 GTRFGAM 66
>XP_006722542
          Length = 1273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    GTRVGA 6
            GTRVGA
Sbjct: 1047 GTRVGA 1052
>XP_005258336
          Length = 1286

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    GTRVGA 6
            GTRVGA
Sbjct: 1030 GTRVGA 1035
>XP_005258335
          Length = 1295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    GTRVGA 6
            GTRVGA
Sbjct: 1047 GTRVGA 1052
>XP_005258334
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    GTRVGA 6
            GTRVGA
Sbjct: 1047 GTRVGA 1052
>XP_005255095
          Length = 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GTRVGAM 7
          GTR GAM
Sbjct: 84 GTRFGAM 90
>XP_005247964
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 88 GTRTGAIRI 96
>XP_006713889
          Length = 1186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 88 GTRTGAIRI 96
>XP_006713888
          Length = 1186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 88 GTRTGAIRI 96
>NP_001036097
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTRVGAMA 8
          GT+ GAMA
Sbjct: 4  GTQEGAMA 11
>NP_001036098
          Length = 158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTRVGAMA 8
          GT+ GAMA
Sbjct: 4  GTQEGAMA 11
>NP_219489
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTRVGAMA 8
          GT+ GAMA
Sbjct: 4  GTQEGAMA 11
>NP_690857
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTRVGAMA 8
          GT+ GAMA
Sbjct: 4  GTQEGAMA 11
>NP_612361
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TRVGAMAI 9
           TR+GA+A+
Sbjct: 290 TRLGALAL 297
>NP_149034
          Length = 600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GTR G+M I
Sbjct: 550 GTRSGSMLI 558
>NP_001139269
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 652 GSRLGAM 658
>NP_001243452
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GTRVGAM 7
          GTR GAM
Sbjct: 67 GTRRGAM 73
>NP_060768
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GT+  AMAI
Sbjct: 150 GTKQSAMAI 158
>NP_001240622
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GT+  AMAI
Sbjct: 94  GTKQSAMAI 102
>XP_006724202
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTRVGAMA 8
           GT +GA+A
Sbjct: 234 GTHLGALA 241
>XP_005256701
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 52 GTRSGAVKI 60
>XP_005256700
          Length = 1063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 52 GTRSGAVKI 60
>XP_006721100
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 316 GSRLGAM 322
>XP_006721099
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 316 GSRLGAM 322
>XP_006721098
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 584 GSRLGAM 590
>XP_006721097
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 652 GSRLGAM 658
>XP_006721096
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 652 GSRLGAM 658
>XP_006721095
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 652 GSRLGAM 658
>XP_006721094
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTRVGAM 7
           G+R+GAM
Sbjct: 652 GSRLGAM 658
>XP_006710814
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GT+  AMAI
Sbjct: 150 GTKQSAMAI 158
>XP_005271060
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GT+  AMAI
Sbjct: 150 GTKQSAMAI 158
>XP_006710813
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTRVGAMAI 9
           GT+  AMAI
Sbjct: 150 GTKQSAMAI 158
>NP_004131
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          GTR GA+ I
Sbjct: 52 GTRSGAVKI 60
>NP_001397
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GTRVGAMAI 9
          G RVGA+ +
Sbjct: 10 GVRVGALLL 18
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.137    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 309,337
Number of extensions: 284
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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