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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_002606                                                              17    3301
NP_849161                                                              17    4312
NP_055976                                                              16    5631
NP_689818                                                              16    5631
NP_005848                                                              16    5631
XP_006723134                                                           16    5631
XP_006723133                                                           16    5631
XP_006723132                                                           16    5631
XP_006723131                                                           16    5631
XP_006723130                                                           16    5631
XP_006723129                                                           16    5631
NP_037506                                                              16    7355
NP_001155901                                                           16    7355
NP_001243121                                                           16    7355
NP_056379                                                              16    7355
NP_055851                                                              15    9605
NP_003974                                                              15    9605
NP_001070253                                                           15    9605
NP_056042                                                              15    9605
NP_598368                                                              15    9605
XP_006724047                                                           15    9605
XP_006724044                                                           15    9605
XP_006718055                                                           15    9605
XP_006718054                                                           15    9605
XP_005270249                                                           15    9605
XP_006718053                                                           15    9605
XP_005270248                                                           15    9605
NP_112189                                                              15    9605

>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTMSLIFLL 9
            GTMSL FLL
Sbjct: 2941 GTMSLTFLL 2949



>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTMSLIFLL 9
            GTMSL FLL
Sbjct: 2736 GTMSLTFLL 2744



>NP_002606
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G+MS+IF L
Sbjct: 270 GSMSIIFFL 278



>NP_849161
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GTMSLIF 7
           GTM+LIF
Sbjct: 431 GTMALIF 437



>NP_055976
          Length = 203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GTMSLIFLL 9
          G +SL+FL+
Sbjct: 50 GVVSLVFLI 58



>NP_689818
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>NP_005848
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TMSLIFLL 9
           T SL+FLL
Sbjct: 121 TQSLVFLL 128



>XP_006723134
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>XP_006723133
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>XP_006723132
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>XP_006723131
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>XP_006723130
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>XP_006723129
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTMSLIFLL 9
           G +SL+FL+
Sbjct: 235 GRLSLVFLI 243



>NP_037506
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTMSLIFL 8
           GT+SLI L
Sbjct: 185 GTLSLIML 192



>NP_001155901
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTMSLIFL 8
           GT+SLI L
Sbjct: 185 GTLSLIML 192



>NP_001243121
          Length = 271

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTMSLIFL 8
           GT+SLI L
Sbjct: 185 GTLSLIML 192



>NP_056379
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTMSLIF 7
           GTM+L+F
Sbjct: 426 GTMALLF 432



>NP_055851
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GTMSLIF 7
           GT+SL+F
Sbjct: 461 GTVSLLF 467



>NP_003974
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TMSLIFLL 9
           TM+LI+L+
Sbjct: 375 TMALIYLI 382



>NP_001070253
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TMSLIFLL 9
           TM+LI+L+
Sbjct: 375 TMALIYLI 382



>NP_056042
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TMSLIFLL 9
          T+S +FLL
Sbjct: 3  TLSFVFLL 10



>NP_598368
          Length = 429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TMSLIFLL 9
          T+S +FLL
Sbjct: 3  TLSFVFLL 10



>XP_006724047
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TMSLIFLL 9
          T+S +FLL
Sbjct: 3  TLSFVFLL 10



>XP_006724044
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  TMSLIFLL 9
          T+S +FLL
Sbjct: 3  TLSFVFLL 10



>XP_006718055
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 96  GTIVLIFFL 104



>XP_006718054
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 96  GTIVLIFFL 104



>XP_005270249
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 96  GTIVLIFFL 104



>XP_006718053
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 103 GTIVLIFFL 111



>XP_005270248
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 132 GTIVLIFFL 140



>NP_112189
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTMSLIFLL 9
           GT+ LIF L
Sbjct: 96  GTIVLIFFL 104



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.156    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 320,106
Number of extensions: 496
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)