Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     299
NP_001089                                                              17    3301
NP_001135820                                                           17    4312
XP_005275697                                                           17    4312
NP_000403                                                              16    7355
NP_001094385                                                           16    7355
XP_005255865                                                           16    7355
XP_006721206                                                           16    7355
XP_005247472                                                           16    7355
NP_001315                                                              16    7355
NP_001028693                                                           16    7355
NP_001028694                                                           16    7355
NP_919268                                                              16    7355
NP_056250                                                              15    9605
NP_001275959                                                           15    9605
NP_001026970                                                           15    9605
NP_690866                                                              15    9605
NP_839955                                                              15    9605
NP_699172                                                              15    9605
NP_001120833                                                           15    9605
NP_001267468                                                           15    9605
NP_001020095                                                           15    9605
NP_002035                                                              15    9605
NP_904355                                                              15    9605
NP_002194                                                              15    9605
NP_001105                                                              15    9605
NP_001001556                                                           15    9605
NP_001275960                                                           15    9605
XP_005255842                                                           15    9605
XP_006721191                                                           15    9605
XP_005255841                                                           15    9605
XP_005255840                                                           15    9605
XP_005255839                                                           15    9605
XP_005255837                                                           15    9605
XP_005255838                                                           15    9605
XP_005255836                                                           15    9605
XP_006720525                                                           15    9605
XP_005254337                                                           15    9605
XP_006720524                                                           15    9605
XP_005254336                                                           15    9605
XP_005250911                                                           15    9605
XP_005250910                                                           15    9605
XP_005265807                                                           15    9605
XP_006714105                                                           15    9605
XP_005265805                                                           15    9605
XP_005265804                                                           15    9605
XP_006710421                                                           15    9605
XP_006710420                                                           15    9605
XP_005270517                                                           15    9605
XP_006710419                                                           15    9605
NP_060731                                                              15    9605
NP_006764                                                              15    9605
>NP_004251
          Length = 1208

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GTGVLVEFN 9
            GTGVLVEF+
Sbjct: 1023 GTGVLVEFS 1031
>NP_001089
          Length = 780

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GTGVLVEFN 9
           GTG +VE++
Sbjct: 260 GTGAIVEYH 268
>NP_001135820
          Length = 94

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GTGVLVE 7
          GTG+LVE
Sbjct: 16 GTGLLVE 22
>XP_005275697
          Length = 124

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTGVLVEFN 9
          GT V V+FN
Sbjct: 5  GTAVRVDFN 13
>NP_000403
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GTG  V+F+
Sbjct: 191 GTGYFVDFS 199
>NP_001094385
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G G LVEF+
Sbjct: 517 GPGSLVEFS 525
>XP_005255865
          Length = 917

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G G LVEF+
Sbjct: 517 GPGSLVEFS 525
>XP_006721206
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G G LVEF+
Sbjct: 512 GPGSLVEFS 520
>XP_005247472
          Length = 533

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GTG  V+F+
Sbjct: 191 GTGYFVDFS 199
>NP_001315
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GTGVLVEFN 9
          GTG+ +EF+
Sbjct: 78 GTGIDLEFD 86
>NP_001028693
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GTGVLVEFN 9
          GTG+ +EF+
Sbjct: 78 GTGIDLEFD 86
>NP_001028694
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GTGVLVEFN 9
          GTG+ +EF+
Sbjct: 78 GTGIDLEFD 86
>NP_919268
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G+G  V+FN
Sbjct: 554 GSGTKVQFN 562
>NP_056250
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 467 GKGVRIEFD 475
>NP_001275959
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 176 GTAKLIEFS 184
>NP_001026970
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GTGVLVEFN 9
          G+G  +EFN
Sbjct: 60 GSGFGIEFN 68
>NP_690866
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GTGVLVEFN 9
          G+G  +EFN
Sbjct: 60 GSGFGIEFN 68
>NP_839955
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 856 GSGVTMEF 863
>NP_699172
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 453 GKGVKIEFD 461
>NP_001120833
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 452 GKGVKIEFD 460
>NP_001267468
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 467 GKGVRIEFD 475
>NP_001020095
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 871 GSGVTMEF 878
>NP_002035
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 200 GTAKLIEFS 208
>NP_904355
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 467 GKGVRIEFD 475
>NP_002194
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TGVLVEFN 9
           TG++V+F+
Sbjct: 839 TGIVVDFS 846
>NP_001105
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>NP_001001556
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 189 GTAKLIEFS 197
>NP_001275960
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 176 GTAKLIEFS 184
>XP_005255842
          Length = 880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 762 GVMVEFS 768
>XP_006721191
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 790 GVMVEFS 796
>XP_005255841
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255840
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255839
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255837
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255838
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_005255836
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GVLVEFN 9
           GV+VEF+
Sbjct: 962 GVMVEFS 968
>XP_006720525
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 176 GTAKLIEFS 184
>XP_005254337
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 189 GTAKLIEFS 197
>XP_006720524
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 200 GTAKLIEFS 208
>XP_005254336
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           GT  L+EF+
Sbjct: 200 GTAKLIEFS 208
>XP_005250911
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 157 GKGVRIEFD 165
>XP_005250910
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 467 GKGVRIEFD 475
>XP_005265807
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 856 GSGVTMEF 863
>XP_006714105
          Length = 897

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 874 GSGVTMEF 881
>XP_005265805
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 889 GSGVTMEF 896
>XP_005265804
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 889 GSGVTMEF 896
>XP_006710421
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 453 GKGVKIEFD 461
>XP_006710420
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 453 GKGVKIEFD 461
>XP_005270517
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 452 GKGVKIEFD 460
>XP_006710419
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGVLVEFN 9
           G GV +EF+
Sbjct: 453 GKGVKIEFD 461
>NP_060731
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTGVLVEF 8
           G+GV +EF
Sbjct: 871 GSGVTMEF 878
>NP_006764
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GTGVLV 6
           GTGVL+
Sbjct: 251 GTGVLI 256
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.146    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 655,727
Number of extensions: 1322
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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