Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     509
NP_444254                                                              20     509
NP_444253                                                              20     509
NP_444255                                                              20     509
XP_005247551                                                           20     509
XP_005247550                                                           20     509
XP_006713712                                                           20     509
XP_005247549                                                           20     509
NP_065978                                                              17    4312
NP_059344                                                              17    4312
NP_006331                                                              17    4312
NP_059345                                                              17    4312
XP_005257005                                                           17    4312
XP_006721701                                                           17    4312
XP_006721700                                                           17    4312
XP_005257002                                                           17    4312
XP_005257001                                                           17    4312
XP_006721699                                                           17    4312
XP_006721698                                                           17    4312
XP_005257000                                                           17    4312
NP_001138360                                                           17    4312
NP_828848                                                              17    4312
NP_001257545                                                           16    5631
NP_002754                                                              16    5631
XP_006711518                                                           16    5631
XP_005273252                                                           16    5631
XP_005273253                                                           16    5631
XP_005273251                                                           16    5631
NP_001138432                                                           16    5631
NP_038479                                                              16    7355
NP_579899                                                              16    7355
NP_937870                                                              16    7355
NP_937872                                                              16    7355
XP_006717823                                                           16    7355
XP_005269751                                                           16    7355
XP_005269750                                                           16    7355
XP_006713970                                                           16    7355
XP_006713969                                                           16    7355
XP_006713968                                                           16    7355
NP_002917                                                              16    7355
NP_003918                                                              15    9605
NP_001268383                                                           15    9605
NP_001268382                                                           15    9605
XP_006713701                                                           15    9605
XP_005247511                                                           15    9605
>NP_444256
          Length = 1794

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1026 GTAPAFKQK 1034
>NP_444254
          Length = 1845

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1026 GTAPAFKQK 1034
>NP_444253
          Length = 1914

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1095 GTAPAFKQK 1103
>NP_444255
          Length = 1863

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1095 GTAPAFKQK 1103
>XP_005247551
          Length = 1855

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1036 GTAPAFKQK 1044
>XP_005247550
          Length = 1856

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1105 GTAPAFKQK 1113
>XP_006713712
          Length = 1923

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1105 GTAPAFKQK 1113
>XP_005247549
          Length = 1924

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GTASAFKQK 9
            GTA AFKQK
Sbjct: 1105 GTAPAFKQK 1113
>NP_065978
          Length = 419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTASAFKQK 9
           GTAS FK +
Sbjct: 211 GTASTFKHE 219
>NP_059344
          Length = 521

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 482 TASGFKQR 489
>NP_006331
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 482 TASGFKQR 489
>NP_059345
          Length = 552

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 482 TASGFKQR 489
>XP_005257005
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 483 TASGFKQR 490
>XP_006721701
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 477 TASGFKQR 484
>XP_006721700
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 483 TASGFKQR 490
>XP_005257002
          Length = 553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 515 TASGFKQR 522
>XP_005257001
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 515 TASGFKQR 522
>XP_006721699
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 516 TASGFKQR 523
>XP_006721698
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 516 TASGFKQR 523
>XP_005257000
          Length = 567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 515 TASGFKQR 522
>NP_001138360
          Length = 534

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TASAFKQK 9
           TAS FKQ+
Sbjct: 482 TASGFKQR 489
>NP_828848
          Length = 818

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GTASAFK 7
           GTASAF+
Sbjct: 202 GTASAFR 208
>NP_001257545
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>NP_002754
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>XP_006711518
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>XP_005273252
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>XP_005273253
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>XP_005273251
          Length = 738

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GTASAFKQK 9
          GTASAF  K
Sbjct: 28 GTASAFFAK 36
>NP_001138432
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ASAFKQK 9
           ASAFK+K
Sbjct: 501 ASAFKEK 507
>NP_038479
          Length = 2061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TASAFKQK 9
            TAS F+QK
Sbjct: 1937 TASLFEQK 1944
>NP_579899
          Length = 2048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TASAFKQK 9
            TAS F+QK
Sbjct: 1924 TASLFEQK 1931
>NP_937870
          Length = 799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GTASAFKQK 9
           G ASA KQK
Sbjct: 461 GKASADKQK 469
>NP_937872
          Length = 1447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GTASAFKQK 9
            G ASA KQK
Sbjct: 1109 GKASADKQK 1117
>XP_006717823
          Length = 1938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TASAFKQK 9
            TAS F+QK
Sbjct: 1814 TASLFEQK 1821
>XP_005269751
          Length = 2067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TASAFKQK 9
            TAS F+QK
Sbjct: 1943 TASLFEQK 1950
>XP_005269750
          Length = 2080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TASAFKQK 9
            TAS F+QK
Sbjct: 1956 TASLFEQK 1963
>XP_006713970
          Length = 646

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GTASAFKQK 9
           G ASA KQK
Sbjct: 308 GKASADKQK 316
>XP_006713969
          Length = 1157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GTASAFKQK 9
            G ASA KQK
Sbjct: 1109 GKASADKQK 1117
>XP_006713968
          Length = 1447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GTASAFKQK 9
            G ASA KQK
Sbjct: 1109 GKASADKQK 1117
>NP_002917
          Length = 1376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GTASAFKQK 9
            G ASA KQK
Sbjct: 1109 GKASADKQK 1117
>NP_003918
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TASAFKQ 8
           TAS FKQ
Sbjct: 248 TASIFKQ 254
>NP_001268383
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TASAFKQ 8
          TAS FKQ
Sbjct: 72 TASIFKQ 78
>NP_001268382
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TASAFKQ 8
           TAS FKQ
Sbjct: 104 TASIFKQ 110
>XP_006713701
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GTASAFKQK 9
           GT   FKQK
Sbjct: 321 GTTVHFKQK 329
>XP_005247511
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GTASAFKQK 9
           GT   FKQK
Sbjct: 321 GTTVHFKQK 329
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.113    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 418,373
Number of extensions: 578
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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