Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              19     869
NP_758961                                                              16    7355
NP_001138825                                                           16    7355
NP_005631                                                              16    7355
XP_005258397                                                           16    7355
XP_005258396                                                           16    7355
XP_006722591                                                           16    7355
XP_005266333                                                           16    7355
XP_005266334                                                           16    7355
NP_001195                                                              15    9605
NP_001099001                                                           15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
NP_000520                                                              15    9605
XP_005248808                                                           15    9605
XP_005248807                                                           15    9605
XP_005248806                                                           15    9605
XP_005248805                                                           15    9605
XP_005248804                                                           15    9605
XP_005248803                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
>NP_003290
          Length = 803

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GTAITLVLK 9
           GT ITLVLK
Sbjct: 244 GTTITLVLK 252
>NP_758961
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTAITLVLK 9
           GT IT V+K
Sbjct: 550 GTVITSVIK 558
>NP_001138825
          Length = 595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTAITLVLK 9
           GT IT V+K
Sbjct: 526 GTVITSVIK 534
>NP_005631
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTAITLVL 8
           GTA+TL L
Sbjct: 459 GTAVTLSL 466
>XP_005258397
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTAITLVL 8
           GTA+TL L
Sbjct: 459 GTAVTLSL 466
>XP_005258396
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTAITLVL 8
           GTA+TL L
Sbjct: 459 GTAVTLSL 466
>XP_006722591
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTAITLVL 8
           GTA+TL L
Sbjct: 459 GTAVTLSL 466
>XP_005266333
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTAITLVLK 9
           GT IT V+K
Sbjct: 550 GTVITSVIK 558
>XP_005266334
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GTAITLVLK 9
           GT IT V+K
Sbjct: 550 GTVITSVIK 558
>NP_001195
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GTAITLVLK 9
            GTA T+V K
Sbjct: 1023 GTATTMVSK 1031
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 766 GTAITL 771
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 749 GTAITL 754
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 962 GTAITL 967
>NP_000520
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GTAITLVL 8
           GT IT+V+
Sbjct: 160 GTGITMVI 167
>XP_005248808
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 568 GTAITL 573
>XP_005248807
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 629 GTAITL 634
>XP_005248806
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 764 GTAITL 769
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 792 GTAITL 797
>XP_005248804
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 825 GTAITL 830
>XP_005248803
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 902 GTAITL 907
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 962 GTAITL 967
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 988 GTAITL 993
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GTAITL 6
           GTAITL
Sbjct: 988 GTAITL 993
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.138    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 317,563
Number of extensions: 371
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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