Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              20     390
NP_004765                                                              18    1482
NP_001014364                                                           18    1482
XP_005257522                                                           18    1482
NP_005322                                                              17    4312
NP_004963                                                              16    5631
NP_037425                                                              16    5631
NP_073752                                                              16    5631
XP_006720709                                                           16    5631
XP_005254660                                                           16    5631
XP_005251512                                                           16    5631
NP_000549                                                              15    9605
NP_001137411                                                           15    9605
NP_001137410                                                           15    9605
NP_000508                                                              15    9605
NP_694945                                                              15    9605
NP_001257293                                                           15    9605
NP_003704                                                              15    9605
NP_001229338                                                           15    9605
NP_036322                                                              15    9605
NP_001257294                                                           15    9605
NP_001229761                                                           15    9605
NP_689502                                                              15    9605
NP_115765                                                              15    9605
NP_001399                                                              15    9605
NP_001254824                                                           15    9605
NP_073588                                                              15    9605
NP_597712                                                              15    9605
XP_005261390                                                           15    9605
XP_006724197                                                           15    9605
XP_006724196                                                           15    9605
XP_005261387                                                           15    9605
XP_005261386                                                           15    9605
XP_006724195                                                           15    9605
XP_005261385                                                           15    9605
XP_006723002                                                           15    9605
XP_005260208                                                           15    9605
XP_005260207                                                           15    9605
XP_006723001                                                           15    9605
XP_006721233                                                           15    9605
XP_005271730                                                           15    9605
XP_005253225                                                           15    9605
XP_006718409                                                           15    9605
XP_005253224                                                           15    9605
XP_005253223                                                           15    9605
XP_006713545                                                           15    9605
XP_006713544                                                           15    9605
XP_006710468                                                           15    9605
XP_005270637                                                           15    9605
NP_114171                                                              15    9605
>NP_443179
          Length = 2170

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SSRVSKHG 9
           SSRVSKHG
Sbjct: 414 SSRVSKHG 421
>NP_004765
          Length = 1581

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSRVSKHG 9
            GSS ++KHG
Sbjct: 1154 GSSPITKHG 1162
>NP_001014364
          Length = 2391

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GSSRVSKHG 9
            GSS+V KHG
Sbjct: 2339 GSSQVWKHG 2347
>XP_005257522
          Length = 1409

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GSS ++KHG
Sbjct: 982 GSSPITKHG 990
>NP_005322
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GSSRVSKHG 9
          GSS+V  HG
Sbjct: 52 GSSQVRAHG 60
>NP_004963
          Length = 1132

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           GS+R  +HG
Sbjct: 127 GSNRAYRHG 135
>NP_037425
          Length = 282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  SRVSKH 8
          SRVSKH
Sbjct: 40 SRVSKH 45
>NP_073752
          Length = 1460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GSSRVSKHG 9
            G+S VS HG
Sbjct: 1073 GNSSVSGHG 1081
>XP_006720709
          Length = 1189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           G+S VS HG
Sbjct: 802 GNSSVSGHG 810
>XP_005254660
          Length = 1460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GSSRVSKHG 9
            G+S VS HG
Sbjct: 1073 GNSSVSGHG 1081
>XP_005251512
          Length = 1132

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           GS+R  +HG
Sbjct: 127 GSNRAYRHG 135
>NP_000549
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSSRVSKHG 9
          GS++V  HG
Sbjct: 52 GSAQVKGHG 60
>NP_001137411
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GSSRVSKH 8
           G+SR+++H
Sbjct: 406 GNSRLARH 413
>NP_001137410
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GSSRVSKH 8
           G+SR+++H
Sbjct: 393 GNSRLARH 400
>NP_000508
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSSRVSKHG 9
          GS++V  HG
Sbjct: 52 GSAQVKGHG 60
>NP_694945
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           GS+RVS  G
Sbjct: 182 GSTRVSLEG 190
>NP_001257293
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           GS+ V KH
Sbjct: 660 GSTEVGKH 667
>NP_003704
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           G SRVS H
Sbjct: 242 GLSRVSDH 249
>NP_001229338
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           G+S V+ HG
Sbjct: 397 GNSEVNLHG 405
>NP_036322
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           GS+ V KH
Sbjct: 650 GSTEVGKH 657
>NP_001257294
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           GS+ V KH
Sbjct: 549 GSTEVGKH 556
>NP_001229761
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>NP_689502
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSRVSKH 8
           SSR+S+H
Sbjct: 461 SSRLSRH 467
>NP_115765
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>NP_001399
          Length = 2923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GSSRVSKHG 9
            GSS V+ HG
Sbjct: 1621 GSSLVAWHG 1629
>NP_001254824
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 267 ARISQHG 273
>NP_073588
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GSSRVSKHG 9
           G+S V+ HG
Sbjct: 397 GNSEVNLHG 405
>NP_597712
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 269 ARISQHG 275
>XP_005261390
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 150 ARISQHG 156
>XP_006724197
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 153 ARISQHG 159
>XP_006724196
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 185 ARISQHG 191
>XP_005261387
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 269 ARISQHG 275
>XP_005261386
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 241 ARISQHG 247
>XP_006724195
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 269 ARISQHG 275
>XP_005261385
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   SRVSKHG 9
           +R+S+HG
Sbjct: 269 ARISQHG 275
>XP_006723002
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSRVSKH 8
           SSR+S+H
Sbjct: 240 SSRLSRH 246
>XP_005260208
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSRVSKH 8
           SSR+S+H
Sbjct: 354 SSRLSRH 360
>XP_005260207
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSRVSKH 8
           SSR+S+H
Sbjct: 461 SSRLSRH 467
>XP_006723001
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   SSRVSKH 8
           SSR+S+H
Sbjct: 467 SSRLSRH 473
>XP_006721233
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   SRVSKHG 9
           SR+ +HG
Sbjct: 328 SRIGRHG 334
>XP_005271730
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SRVSKHG 9
           SRV +HG
Sbjct: 266 SRVKEHG 272
>XP_005253225
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>XP_006718409
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>XP_005253224
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>XP_005253223
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GSSRVSKHG 9
           GS+ +++HG
Sbjct: 122 GSAALARHG 130
>XP_006713545
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           GS+ V KH
Sbjct: 648 GSTEVGKH 655
>XP_006713544
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GSSRVSKH 8
           GS+ V KH
Sbjct: 650 GSTEVGKH 657
>XP_006710468
          Length = 2916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GSSRVSKHG 9
            GSS V+ HG
Sbjct: 1621 GSSLVAWHG 1629
>XP_005270637
          Length = 2921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GSSRVSKHG 9
            GSS V+ HG
Sbjct: 1621 GSSLVAWHG 1629
>NP_114171
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSRVSKH 8
           SSR SKH
Sbjct: 336 SSRKSKH 342
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.119    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 475,620
Number of extensions: 872
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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