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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_149111                                                              17    2528
NP_001258011                                                           17    2528
XP_006725072                                                           17    2528
XP_006725071                                                           17    2528
XP_006725070                                                           17    2528
XP_005248440                                                           17    2528
XP_006714568                                                           17    2528
XP_005248439                                                           17    2528
NP_001120727                                                           17    4312
NP_631915                                                              17    4312
XP_006726254                                                           17    4312
XP_006726253                                                           17    4312
XP_006726252                                                           17    4312
XP_006726214                                                           17    4312
XP_006726213                                                           17    4312
XP_006726212                                                           17    4312
XP_006726371                                                           17    4312
XP_006726370                                                           17    4312
XP_006726116                                                           17    4312
XP_006726115                                                           17    4312
XP_006726114                                                           17    4312
XP_006726017                                                           17    4312
XP_006726016                                                           17    4312
XP_006726015                                                           17    4312
XP_006725929                                                           17    4312
XP_006725928                                                           17    4312
XP_006725927                                                           17    4312
XP_006725828                                                           17    4312
XP_006725827                                                           17    4312
XP_006725826                                                           17    4312
XP_006725701                                                           17    4312
XP_006725700                                                           17    4312
XP_006725699                                                           17    4312
XP_006726334                                                           17    4312
XP_006726333                                                           17    4312
XP_006726332                                                           17    4312
XP_006723139                                                           17    4312
XP_006723138                                                           17    4312
XP_006723137                                                           17    4312
NP_002763                                                              16    5631
NP_149110                                                              16    5631
XP_005256268                                                           16    5631

>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            G SKLLRMK
Sbjct: 3647 GGSKLLRMK 3655



>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            G SKLLRMK
Sbjct: 3647 GGSKLLRMK 3655



>NP_149111
          Length = 451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>NP_001258011
          Length = 311

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_006725072
          Length = 360

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_006725071
          Length = 440

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_006725070
          Length = 500

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_005248440
          Length = 360

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_006714568
          Length = 440

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>XP_005248439
          Length = 500

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GSSK LR+K
Sbjct: 164 GSSKTLRVK 172



>NP_001120727
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>NP_631915
          Length = 1009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 960 GSLKILRLK 968



>XP_006726254
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726253
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726252
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006726214
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726213
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726212
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006726371
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726370
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726116
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726115
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726114
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006726017
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726016
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726015
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006725929
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725928
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725927
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006725828
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725827
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725826
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006725701
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725700
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006725699
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006726334
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726333
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006726332
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>XP_006723139
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006723138
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSSKLLRMK 9
           GS K+LR+K
Sbjct: 988 GSLKILRLK 996



>XP_006723137
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSSKLLRMK 9
            GS K+LR+K
Sbjct: 1015 GSLKILRLK 1023



>NP_002763
          Length = 1019

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSSKLLR 7
           GSSK+LR
Sbjct: 287 GSSKILR 293



>NP_149110
          Length = 470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SSKLLRMK 9
           SSK+LR+K
Sbjct: 177 SSKMLRVK 184



>XP_005256268
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SSKLLRMK 9
          SSK+LR+K
Sbjct: 73 SSKMLRVK 80



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.127    0.313 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 369,174
Number of extensions: 499
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)