Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_066010                                                              18    1135
NP_077014                                                              17    2528
NP_064450                                                              17    2528
XP_005255628                                                           17    2528
XP_005255627                                                           17    2528
XP_005273257                                                           17    2528
NP_079235                                                              17    3301
XP_006719671                                                           17    3301
XP_006719670                                                           17    3301
NP_000486                                                              17    4312
NP_203699                                                              17    4312
NP_001836                                                              17    4312
NP_055784                                                              17    4312
NP_001136022                                                           17    4312
NP_001136023                                                           17    4312
NP_003103                                                              17    4312
XP_005262127                                                           17    4312
XP_006724679                                                           17    4312
XP_005249885                                                           17    4312
XP_006710524                                                           17    4312
XP_006710523                                                           17    4312
NP_001611                                                              16    7355
NP_001136074                                                           16    7355
NP_001136073                                                           16    7355
NP_892010                                                              16    7355
NP_068807                                                              16    7355
XP_005257823                                                           16    7355
XP_006718751                                                           16    7355
XP_006718750                                                           16    7355
XP_005274303                                                           16    7355
XP_006718749                                                           16    7355
XP_005274302                                                           16    7355
XP_005274301                                                           16    7355
XP_005274300                                                           16    7355
XP_005274299                                                           16    7355
XP_005274298                                                           16    7355
XP_005274297                                                           16    7355
XP_005272414                                                           16    7355
XP_006710356                                                           16    7355
XP_005270419                                                           16    7355
XP_005270421                                                           16    7355
NP_006338                                                              16    7355
NP_001191088                                                           15    9605
NP_001191089                                                           15    9605
NP_064511                                                              15    9605
NP_001230805                                                           15    9605
NP_001191087                                                           15    9605
NP_000082                                                              15    9605
NP_004986                                                              15    9605
NP_861441                                                              15    9605
NP_004590                                                              15    9605
NP_065796                                                              15    9605
NP_001014980                                                           15    9605
XP_006724373                                                           15    9605
XP_006723357                                                           15    9605
XP_006723356                                                           15    9605
XP_006723355                                                           15    9605
XP_006723354                                                           15    9605
XP_006723353                                                           15    9605
XP_006720920                                                           15    9605
XP_005249302                                                           15    9605
XP_006714819                                                           15    9605
XP_005246334                                                           15    9605
XP_005246332                                                           15    9605
XP_005271001                                                           15    9605
NP_001034546                                                           15    9605
NP_004038                                                              15    9605
>NP_066010
          Length = 1232

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GSGTALASV 9
            GSGTALA V
Sbjct: 1109 GSGTALAPV 1117
>NP_077014
          Length = 404

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSGTALASV 9
           G+GT LAS+
Sbjct: 213 GAGTGLASI 221
>NP_064450
          Length = 1722

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GSGTALASV 9
           GS TALASV
Sbjct: 454 GSRTALASV 462
>XP_005255628
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSGTALASV 9
           G+GT LAS+
Sbjct: 213 GAGTGLASI 221
>XP_005255627
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSGTALASV 9
           G+GT LAS+
Sbjct: 213 GAGTGLASI 221
>XP_005273257
          Length = 1726

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GSGTALASV 9
           GS TALASV
Sbjct: 454 GSRTALASV 462
>NP_079235
          Length = 584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGTALASV 9
           +GTALASV
Sbjct: 397 AGTALASV 404
>XP_006719671
          Length = 584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGTALASV 9
           +GTALASV
Sbjct: 397 AGTALASV 404
>XP_006719670
          Length = 389

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SGTALASV 9
           +GTALASV
Sbjct: 202 AGTALASV 209
>NP_000486
          Length = 1685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG ALAS
Sbjct: 1609 GSGQALAS 1616
>NP_203699
          Length = 1691

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG ALAS
Sbjct: 1615 GSGQALAS 1622
>NP_001836
          Length = 1669

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG ALAS
Sbjct: 1593 GSGQALAS 1600
>NP_055784
          Length = 920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GSGTALASV 9
           G+G+A+ASV
Sbjct: 799 GTGSAVASV 807
>NP_001136022
          Length = 927

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GSGTALASV 9
           G+G+A+ASV
Sbjct: 806 GTGSAVASV 814
>NP_001136023
          Length = 919

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GSGTALASV 9
           G+G+A+ASV
Sbjct: 798 GTGSAVASV 806
>NP_003103
          Length = 784

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSGTALASV 9
           G GTALA V
Sbjct: 734 GGGTALAIV 742
>XP_005262127
          Length = 1688

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG ALAS
Sbjct: 1612 GSGQALAS 1619
>XP_006724679
          Length = 1691

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG ALAS
Sbjct: 1615 GSGQALAS 1622
>XP_005249885
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSGTALASV 9
           G GTALA V
Sbjct: 717 GGGTALAIV 725
>XP_006710524
          Length = 921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GSGTALASV 9
           G+G+A+ASV
Sbjct: 800 GTGSAVASV 808
>XP_006710523
          Length = 922

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GSGTALASV 9
           G+G+A+ASV
Sbjct: 801 GTGSAVASV 809
>NP_001611
          Length = 5890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5850 GSGVSLAS 5857
>NP_001136074
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG ALA+
Sbjct: 111 GSGNALAA 118
>NP_001136073
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG ALA+
Sbjct: 111 GSGNALAA 118
>NP_892010
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG ALA+
Sbjct: 197 GSGNALAA 204
>NP_068807
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG ALA+
Sbjct: 125 GSGNALAA 132
>XP_005257823
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG ALA+
Sbjct: 111 GSGNALAA 118
>XP_006718751
          Length = 3489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 3449 GSGVSLAS 3456
>XP_006718750
          Length = 4001

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 3961 GSGVSLAS 3968
>XP_005274303
          Length = 4506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 4466 GSGVSLAS 4473
>XP_006718749
          Length = 4596

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 4556 GSGVSLAS 4563
>XP_005274302
          Length = 5438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5398 GSGVSLAS 5405
>XP_005274301
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5722 GSGVSLAS 5729
>XP_005274300
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5722 GSGVSLAS 5729
>XP_005274299
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5722 GSGVSLAS 5729
>XP_005274298
          Length = 5890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5850 GSGVSLAS 5857
>XP_005274297
          Length = 5890

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            GSG +LAS
Sbjct: 5850 GSGVSLAS 5857
>XP_005272414
          Length = 791

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSGTALA 7
           GSG+ALA
Sbjct: 778 GSGSALA 784
>XP_006710356
          Length = 177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSGTALASV 9
          G GT +AS+
Sbjct: 82 GDGTGVASI 90
>XP_005270419
          Length = 177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSGTALASV 9
          G GT +AS+
Sbjct: 82 GDGTGVASI 90
>XP_005270421
          Length = 177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSGTALASV 9
          G GT +AS+
Sbjct: 82 GDGTGVASI 90
>NP_006338
          Length = 177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GSGTALASV 9
          G GT +AS+
Sbjct: 82 GDGTGVASI 90
>NP_001191088
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 277 GSGNALA 283
>NP_001191089
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 241 GSGNALA 247
>NP_064511
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 277 GSGNALA 283
>NP_001230805
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GSGTALA 7
          GSG ALA
Sbjct: 71 GSGNALA 77
>NP_001191087
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 218 GSGNALA 224
>NP_000082
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            G+G ALAS
Sbjct: 1593 GTGQALAS 1600
>NP_004986
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  GTALASV 9
          GTALAS+
Sbjct: 19 GTALASL 25
>NP_861441
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGTALASV 9
           SGTALA +
Sbjct: 414 SGTALALI 421
>NP_004590
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            G GTA+A+
Sbjct: 1133 GGGTAIAA 1140
>NP_065796
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GTALASV 9
           GTA+ASV
Sbjct: 543 GTAVASV 549
>NP_001014980
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GSGTALAS 8
           GSG +LAS
Sbjct: 187 GSGLSLAS 194
>XP_006724373
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            G GTA+A+
Sbjct: 1103 GGGTAIAA 1110
>XP_006723357
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GSGTALA 7
          GSG ALA
Sbjct: 71 GSGNALA 77
>XP_006723356
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 218 GSGNALA 224
>XP_006723355
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 241 GSGNALA 247
>XP_006723354
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 277 GSGNALA 283
>XP_006723353
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 339 GSGNALA 345
>XP_006720920
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GSGTALAS 8
          GSGTA+ +
Sbjct: 36 GSGTAMVT 43
>XP_005249302
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   GTALASV 9
           GTA+ASV
Sbjct: 446 GTAVASV 452
>XP_006714819
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SGTALASV 9
           SGTALA +
Sbjct: 381 SGTALALI 388
>XP_005246334
          Length = 1635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            G+G ALAS
Sbjct: 1558 GTGQALAS 1565
>XP_005246332
          Length = 1639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GSGTALAS 8
            G+G ALAS
Sbjct: 1562 GTGQALAS 1569
>XP_005271001
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 159 GSGAALA 165
>NP_001034546
          Length = 158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 112 GSGAALA 118
>NP_004038
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSGTALA 7
           GSG ALA
Sbjct: 159 GSGAALA 165
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.115    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,187
Number of extensions: 630
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package